ROSUVASTATIN

作品数：72被引量：595H指数：10
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相关领域：医药卫生更多>>
相关作者：王永红田东华孟红梅王赞姜宏宇更多>>
相关机构：华中科技大学阿斯特拉曾尼卡有限公司武警北京总队医院苏黎世大学更多>>
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相关基金：国家自然科学基金广东省自然科学基金湖北省科技攻关计划更多>>
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Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy
《World Journal of Methodology》2025年第2期137-144,共8页Vandana Tayal Akash Mandal Ijasul Haque M Akhilesh Mishra Bhupinder S Kalra Vandana Roy 
BACKGROUND Epilepsy impacts millions of people,with many not responding to existing treatments.Some evidence links neuroinflammatory processes to epilepsy.Statins exhibit anti-inflammatory and neuroprotective properti...
关键词：ANTIEPILEPTIC ANTICONVULSANT STATINS ROSUVASTATIN Maximal electroshock seizure PENTYLENETETRAZOL 
Pharmacokinetics and Bioequivalence Comparison of Two Fixed-Dose Combination of Rosuvastatin/Ezetimibe Formulations: A Randomized, Crossover, Open-Label Study in Healthy Volunteers
《Journal of Biosciences and Medicines》2024年第10期119-139,共21页José Gregorio Chacón Evelyn Peña Alfredo Inatti 
Objective: To evaluate the bioequivalence (BE) of two fixed-dose combination (FDC) formulations of Rosuvastatin and Ezetimibe: Cresadex® EZE 20/10 mg (Abbott Laboratories) as the reference formulation (R), and Racor® ...
关键词：BIOEQUIVALENCE PHARMACOKINETICS ROSUVASTATIN EZETIMIBE FDC 
Efficacy and safety of 10 mg/d vs.20 mg/d rosuvastatin in elderly patients with coronary heart disease and hyperlipidemia
《South China Journal of Cardiology》2024年第3期149-155,共7页CHEN Hui-qin 
Background Population aging has become a common concern in the world.coronary heart disease(CHD)is one of the major diseases that lead to the death of the elderly and affect the quality of life.Studies have confirmed ...
关键词：Different doses ROSUVASTATIN Old age Coronary heart disease HYPERLIPIDEMIA 
Targeted delivery of rosuvastatin enhances treatment of hyperhomocysteinemia-induced atherosclerosis using macrophage membrane-coated nanoparticles
《Journal of Pharmaceutical Analysis》2024年第9期1301-1319,共19页Dayue Liu Anning Yang Yulin Li Zhenxian Li Peidong You Hongwen Zhang Shangkun Quan Yue Sun Yaling Zeng Shengchao Ma Jiantuan Xiong Yinju Hao Guizhong Li Bin Liu Huiping Zhang Yideng Jiang 
supported by the National Natural Science Foundation of China(Grant Nos.:U21A20343,82160088,81870225,81870332,81700404,82271626,and 82260088);the Natural Science Foundation of Ningxia Autonomous Region,China(Grant Nos.:2020AAC02021,2020AAC02038,and 2022AAC05025);the Key Research and Development Projects in Ningxia Autonomous Region,China(Grant Nos.:2020BFH02003,2021BEG02033,2020BEG03008,and 2022BFH02013);the Basic Scientific Research Operating Expenses from the Public Welfare Research Institutes at the Central Level of the Chinese Academy of Medical Sciences,China(Grant No.:2019PT330002);the Ningxia Science and Technology Leading Talent Project,China(Grant No.:KJT2017007);the Natural Science Foundation of Hunan Province,China(Grant No.:2022JJ40698);the School-level Special Talent Launching Project of Ningxia Medical University,China(Grant No.:XT2018015);the Open Bidding for Selecting the Best Candidates Program of Ningxia Medical University,China(Grant No.:XJKF230106).
Rosuvastatin (RVS) is an excellent drug with anti-inflammatory and lipid-lowering properties in the academic and medical fields. However, this drug faces a series of challenges when used to treat atherosclerosis cause...
关键词：HOMOCYSTEINE ATHEROSCLEROSIS Macrophage membrane Prussian blue nanoparticles Rosuvas tatin Gut microbes 
Pharmacokinetics and Bioequivalence Evaluation of Two Rosuvastatin Calcium 20 mg Tablets: A Single Oral Dose, Randomized-Sequence, Open-Label, Two-Period Crossover Study in Healthy Volunteers under Fasting Conditions
《Journal of Biosciences and Medicines》2024年第6期230-243,共14页Evelyn Pena Alfredo Inatti José Gregorio Chacón 
Objectives: To compare the rate and extent of absorption of Racor® 20 mg (Rosuvastatin calcium 20 mg) tablet of Laboratorios Leti, S.A.V., with Crestor® 20 mg (Rosuvastatin calcium 20 mg) tablet of AstraZeneca, UK Lim...
关键词：BIOEQUIVALENCE ROSUVASTATIN PHARMACOKINETICS 
Influence of Statins and Fibrates Drugs on Bone Health and Regeneration
《Journal of Biomaterials and Nanobiotechnology》2024年第1期1-24,共24页Octavio Santiago Ivan Nadir Camal Ruggieri Marina Ribeiro Paulini Valéria Paula Sassoli Fazan João Paulo Mardegan Issa Sara Feldman 
In the medical and dental field, the importance and need for the study of materials and drugs for use as bone grafts or regeneration in injured areas due to the presence of fractures, infections or tumors that cause e...
关键词：Bone STATINS ROSUVASTATIN Sinvastatin FIBRATES FENOFIBRATE Bone Regeneration 
Rosuvastatin‑Eluting Gold‑Nanoparticle‑Loaded Perivascular Wrap for Enhanced Arteriovenous Fistula Maturation in a Murine Model
《Advanced Fiber Materials》2023年第6期1986-2001,共16页Carleigh Klusman Benjamin Martin Joy Vanessa D.Perez Allan John R.Barcena Marvin R.Bernardino Erin Marie D.San Valentin Jossana A.Damasco Huckie C.Del Mundo Karem A.Court Biana Godin Gino Martin Canlas Natalie Fowlkes Richard Bouchard Jizhong Cheng Steven Y.Huang Marites P.Melancon 
the National Institutes of Health—National Heart,Lung,and Blood Institute(5HL141831-05 and 1R01HL159960-01A1);a Radiological Society of North America Research Seed Grant(RSD2012);a Society of Interventional Radiology Pilot Research Grant,an MD Anderson Center for Advanced Biomedical Imaging Pilot Project Program Research Grant;the National Institutes of Health—National Cancer Institute through MD Anderson's Cancer Center Support Grant(P30CA016672,used the Research Animal Support Facility and Small Animal Imaging Facility).
Arteriovenous fistulas(AVFs)are a vital form of AV access for patients requiring hemodialysis,but they link to overall morbidity and mortality when they fail to mature.The most common cause of AVF non-maturation is ne...
关键词：Arteriovenous fistula Chronic kidney disease Nanoparticles POLYCAPROLACTONE RADIOPACITY ROSUVASTATIN 
Rosuvastatin acts on the lymphatic system to improve atherosclerosis
《China Medical Abstracts(Internal Medicine)》2023年第2期98-98,共1页宋子琪 
Objective To investigate whether rosuvastatin acts on lymphatic system and influences lymphatic systemmediated reverse cholesterol transport to play an an tiatherosclerosis role.Methods Forty-eight apolipoprotein E^(-...
关键词：ATHEROSCLEROSIS LYMPHATIC CHOLESTEROL 
Rosuvastatin suppresses TNF-α-induced matrix catabolism,pyroptosis and senescence via the HMGB1/NF-κB signaling pathway in nucleus pulposus cells被引量：6
《Acta Biochimica et Biophysica Sinica》2023年第5期795-808,共14页Weijian Chen Zhihuai Deng Jianxiong Zhu Liang Yuan Shuangxing Li Yangyang Zhang Jiajun Wu Zhengqi Huang Tianyu Qin Wei Ye 
supported by the grants from the National Natural Science Foundation of China(Nos.81572197 and 82002776);the Natural Science Foundation of Guangdong Province(Nos.2020A1515011538 and 2020A1515010060);the Guangdong Basic and Applied Basic Research Foundation(No.2021A1515010345);Guangzhou Municipal Health Commission:Featured Clinical Technique Project,Yat-sen Qihang Foundation of Sun Yat-sen Memorial Hospital(No.YXQH202204);the Special Project of Guangzhou Basic Research Plan Co-funded by Municipal Schools and Enterprises(No.2023A03J0817).
Intervertebral disc degeneration is mainly caused by irregular matrix metabolism in nucleus pulposus cells and involves inflammatory factors such as TNF-α.Rosuvastatin,which is widely used in the clinic to reduce cho...
关键词：intervertebral disc degeneration ROSUVASTATIN high-mobility group box 1 NF-κB signaling pathway 
Rosuvastatin alleviates renal injury in cardiorenal syndrome model rats through anti-inflammatory and antioxidant pathways
《Emergency and Critical Care Medicine》2022年第4期203-208,共6页Biye Zhou Qiangguo Ao Hua Zhao Ping Ye 
Zhou B from the Innovation Cultivation Fund of the Sixth Medical Center of PLA General Hospital(CXPY201704);the Youth Development Program of the Central Military Commission(20QNPY107).
Background:Cardiorenal syndrome is increasingly common and has been reported to be associated with inflammation and oxidative stress,and statins have anti-inflammatory and antioxidant effects.Therefore,we designed thi...
关键词：Cardiorenal syndrome Heart failure ROSUVASTATIN 
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