ANTICONVULSANT

作品数：34被引量：22H指数：2
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Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy
《World Journal of Methodology》2025年第2期137-144,共8页Vandana Tayal Akash Mandal Ijasul Haque M Akhilesh Mishra Bhupinder S Kalra Vandana Roy 
BACKGROUND Epilepsy impacts millions of people,with many not responding to existing treatments.Some evidence links neuroinflammatory processes to epilepsy.Statins exhibit anti-inflammatory and neuroprotective properti...
关键词：ANTIEPILEPTIC ANTICONVULSANT STATINS ROSUVASTATIN Maximal electroshock seizure PENTYLENETETRAZOL 
Anticonvulsant Effect of Xingnaojing Injection on Acute Seizure Models in Mice被引量：1
《Clinical Complementary Medicine and Pharmacology》2023年第3期31-39,共9页Minjuan Sun Xiaoyun Qiu Zhijian Yuan Shuo Zhang Qi Zhang Xiaoli Da Xuming Ji Xuhong Jiang Cenglin Xu Zhong Chen 
This work was financially supported by the Natural Science Foun-dation of Zhejiang Province(LD22H310003);the National Natural Science Foundation of China(82173796);the Research Project of Zhe-jiang Chinese Medical University(2022JKJNTZ13).
Background:Epilepsy is characterized by acute recurrent seizures.The control of seizures is largely hampered by the tolerance to current anti-seizure drugs.Complementary anti-convulsant pharmacotherapies are urgently ...
关键词：Xingnaojing Injection Epileptic seizure Neuronal excitability Traditional Chinese Medicine 
Anticonvulsant Effects of Chrysanthellum americanum L. (Vatke) Aqueous Extract in Mice Pilocarpine Model of Epilepsy and Associated Memory Impairment: Role of Antioxidant Defense System and Cholinergic Transmission
《Journal of Biosciences and Medicines》2023年第6期81-102,共22页Yvette Nguezeye Fanta Sabine Adeline Yadang Simon Pale Vanessa Tita Jugha Hart Mann Alain Youbi Mambou Raymond Bess Bila Tambong Ako Ojongnkpot Germain Sotoing Taiwe Gabriel Agbor Agbor Elisabeth Ngo Bum 
Chrysanthellum americanum (L.) Vatke is a medicinal plant used by the traditional healers to treat epilepsy and associated memory impairment. This work aims at evaluating the anticonvulsant effects of Chrysanthellum a...
关键词：Chrysanthellum americanum EPILEPSY Memory Impairment Oxidative Stress Cholinergic Transmission 
Anticonvulsant, Sedative and Antidepressant Effects of Aqueous Extract of Costus afer Stems in Mice
《Journal of Biosciences and Medicines》2022年第12期22-31,共10页Bassoueka D’Avila Judicaël Peneme Bonaventure Max Lazard Ondele Radar Ahoudi Jered Abena Ange Antoine 
Epilepsy is a disorder in the nervous system which often causes a loss of consciousness. Traditional treatments are quiet a component of health care system in various populations in spite of the fact that well-establi...
关键词：EPILEPSY SEDATIVE Traditional Medicine ANTIDEPRESSANT ANTICONVULSANT 
Jadwar(Delphinium denudatum Wall.):a medicinal plant
《Traditional Medicine Research》2020年第6期487-497,共11页Roghayeh Baghervand Navid Mehrdad Karimi Morteza Ghojazadeh Seyed Mostafa Araj-Khodaei Alireza Bagherzadeh karimi Sanam Dolati Mehri Bansans Seyed Mohammad Bagher Fazljou 
Delphinium denudatum Wall.is one of the important medicinal herbs of traditional Persian medicine and is known as Jadwar.Medicinal plants are the most widely used drugs in traditional Persian medicine and has been use...
关键词：Delphinium denudatum Wall. Jadwar root Traditional Persian medicine Neurologic and psychiatric effects Anticonvulsant effects 
Molecular Docking Studies on Anticonvulsant Enaminones Inhibiting Voltage-Gated Sodium Channels
《Open Journal of Physical Chemistry》2019年第4期241-257,共17页Yayin Fang Jamiya Kirkland Isis J. Amaye Patrice Jackson-Ayotunde Matthew George Jr. 
Epilepsy is described as the most common chronic brain disorder. A typical symptom of epilepsy results in uncontrolled convulsions caused by temporary excessive neuronal discharges. Although several new anticon-vulsan...
关键词：ANTICONVULSANT ENAMINONES VOLTAGE-GATED Sodium Channels STRUCTURE-BASED Drug Design MOLECULAR DOCKING 3D QSAR 
Eslicarbazepine acetate:A therapeutic agent of paramount importance in acute anticonvulsant therapy
《Journal of Acute Disease》2017年第6期245-254,253,共11页Farah Iram Shah Alam Khan Aftab Ahmad Anees A.Siddiqui Asif Husain 
Eslicarbazepine acetate (ESL) is a new, once daily, orally administered, third generation antiepileptic drug which is indicated in the treatment of partial-onset seizures. ESL is known to exert it's anticonvulsant eff...
关键词：Eslicarbazepine ACETATE Partial-onset seizures EPILEPSY ANTIEPILEPTIC drugs Drug interactions 
Investigation of Some Possible Mechanisms Involved in the Anticonvulsant Activity of Tulbaghia violacea Harv
《Journal of Pharmacy and Pharmacology》2017年第9期616-627,共12页K. A. A. Masoud Okobi E Ekpo G. J. Amabeoku 
Even though Tulbaghia violacea has been used to treat and manage epilepsy in South Africa by traditional medicine practitioners, no evidence in any literature has shown any scientific scrutiny of the effectiveness of ...
关键词：Tulbaghia violacea alliaceae anticonvulsant properties GABAERGIC glutamatergic and glycinergic mechanisms mice. 
Comparison of efficacy of folic acid and silymarin in the management of antiepileptic drug induced liver injury:a randomized clinical trial被引量：2
《Hepatobiliary & Pancreatic Diseases International》2017年第3期296-302,共7页Masoumeh Asgarshirazi Mamak Shariat Mahdi Sheikh 
supported by a grant from the research deputy of Tehran University of Medical Sciences
BACKGROUND： Liver injury associated with antiepileptic drugs accounts for a large proportion of drug-induced liver injuries （DILI） in children. Although withdrawal of the causative agent is the only proved treatmen...
关键词：ANTICONVULSANT ANTIEPILEPTIC ENZYMES HEPATITIS HEPATOTOXICITY 
Anticonvulsant effects of medicinal plants with emphasis on mechanisms of action
《Asian Pacific Journal of Tropical Biomedicine》2017年第2期166-172,共7页Zahra Rabiei 
Funded by the Research and Technology Deputy of the Shahrekord University of Medical Sciences(grant number:2672)
Epilepsy is a disorder in brain in which clusters of nerve cells, or neurons, occasionally signal abnormally and cause strange emotions, sensations, and behavior, or sometimes muscle spasms, convulsions, and loss of c...
关键词：Epileptic seizure ANTICONVULSANT Medicinal plants Oxidative stress 
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