There is an error in the name of the cell line in the abstract of the published paper“MicroRNA-502-3p regulates GABAergic synapse function in hippocampal neurons”published on pages 2698-2707,Issue 12,Volume 19 of Ne...
supported by the National Institute on Aging (NIA);National Institutes of Health (NIH);Nos.K99AG065645,R00AG065645;R00AG065645-04S1 (to SK);NIH research grants,NINDS,No.R01 NS115834;NINDS/NIA,No.R01 NS115834-02S1 (to LG)。
Gamma-aminobutyric acid(GABA)ergic neurons,the most abundant inhibitory neurons in the human brain,have been found to be reduced in many neurological disorders,including Alzheimer's disease and Alzheimer's disease-rel...
supported by grants from the National Key R&D Program of China(2017YFE0103400);the National Natural Science Foundation of China(81470628 and 82471086).
The looming stimulus-evoked flight response to approaching predators is a defensive behavior in most animals. However, how looming stimuli are detected in the retina and transmitted to the brain remains unclear. Here,...
support from the National Natural Science Foundation of China(Grant No.42007370);the Yunnan Major Scientific and Technological Projects(Grant No.202302AO_(3)70001);the Fundamental Research Funds for the Central Universities(Grant No.YJ202315);the Yunnan Fundamental Research Projects(Grant No.202301AT070331).
The coexistence of caffeine(CF)and ketamine(KET)in surface waters across Asia has been widely reported.Previous studies have implied that CF and KET may share a mechanism of action.However,the combined toxicity of the...
Temporal lobe epilepsy(TLE) is a common type of focal epilepsy characterized by seizure foci within the temporal lobes.While surgical resection of the foci is an established and effective approach for controlling seiz...
Striatal interneurons play a key role in modulating striatal-dependent behaviors,including motor activity and reward and emotional processing.Interneurons not only provide modulation to the basal ganglia circuitry und...
This work was supported by grants from STI2030-Major Projects(2021ZD0203400 to Y.Q.Y.);the National Natural Science Foundation of China Major Project(T2293733,T2293730,31970939 to Y.Q.Y.,82288101,82090033,U20A6005 to S.D.);the Natural Science Foundation of Zhejiang Province(LZ22H090001 to Y.Q.Y.,LR24C090001 to H.Y.);the Key R&D Program of Zhejiang Province(2022C03034 to Y.Q.Y.);the CAMS Innovation Fund for Medical Sciences(2019-I2M-5-057 to S.D.);the Non-Profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(2023-PT310-01 to Y.Q.Y.).
The nucleus of Darkschewitsch(ND),mainly composed of GABAergic neurons,is widely recognized as a component of the eye-movement controlling system.However,the functional contribution of ND GABAergic neurons(NDGABA)in a...
This article summarized the research progress on the antidepressant mechanism of icariin II,mainly elaborating on its mechanism from five aspects:GABAergic nervous system,inflammatory response,oxidative stress,neurotr...
supported by funding from National Institutes of Health(R21NS094091);the Brain Research Foundation,and the Protein Folding Disease Initiative of the University of Michigan.
Down syndrome(DS)is caused by the presence of an extra copy of the entire or a portion of human chromosome 21(HSA21).This genomic alteration leads to elevated expression of numerous HSA21 genes,resulting in a variety ...