STRIATUM

作品数：113被引量：191H指数：6
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相关领域：医药卫生更多>>
相关作者：毛利民郭鸣雷王强饶曼人汪海更多>>
相关机构：暨南大学密苏里大学南京医科大学军事医学科学院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
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Activation and polarization of striatal microglia and astrocytes are involved in bradykinesia and allodynia in early-stage parkinsonian mice被引量：1
《Fundamental Research》2024年第4期806-819,共14页Xue Zhang Zi-Lin Shen Ya-Wei Ji Cui Yin Cheng Xiao Chunyi Zhou 
the National Natural Science Foundation of China(81971038,82071231,82171235,82271293,81870891);the Fund for Jiangsu Province Specially-Appointed Professor(C.X.,C.Z.);the Natural Science Foundation of Jiangsu Province(BK20211349);the Leadership Program in Xuzhou Medical University(JBGS202203).
In addition to the cardinal motor symptoms,pain is a major non-motor symptom of Parkinson's disease(PD).Neuroinflammation in the substantia nigra pars compacta and dorsal striatum is involved in neurodegeneration in P...
关键词：Parkinson's disease Dopaminergic system STRIATUM MICROGLIA ASTROCYTES Substantia nigra pars compacta 
The dual role of striatal interneurons:circuit modulation and trophic support for the basal ganglia被引量：3
《Neural Regeneration Research》2024年第6期1277-1283,共7页Elliot Wegman Marlena Wosiski-Kuhn Yu Luo 
Striatal interneurons play a key role in modulating striatal-dependent behaviors,including motor activity and reward and emotional processing.Interneurons not only provide modulation to the basal ganglia circuitry und...
关键词：CHOLINERGIC dopamine GABAERGIC INTERNEURON levodopa-induced dyskinesia PARVALBUMIN sonic hedgehog STRIATUM trophic factor 
The Secondary Motor Cortex-striatum Circuit Contributes to Suppressing Inappropriate Responses in Perceptual Decision Behavior
《Neuroscience Bulletin》2023年第10期1544-1560,共17页Jing Liu Dechen Liu Xiaotian Pu Kexin Zou Taorong Xie Yaping Li Haishan Yao 
This work was supported by the STI2030-Major Projects(2021ZD0203700/2021ZD0203703);the National Natural Science Foundation of China(31771151,32171030,and 32100829),the Lingang Lab(LG202104-01-03);Shanghai Municipal Science and Technology Major Project(2018SHZDZX05);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32010200).
The secondary motor cortex(M2)encodes choice-related information and plays an important role in cue-guided actions.M2 neurons innervate the dorsal striatum(DS),which also contributes to decision-making behavior,yet ho...
关键词：Secondary motor cortex STRIATUM Visual perceptual decision Choice signal Direct and indirect pathway striatal neurons 
Functional Autapses Form in Striatal Parvalbumin Interneurons but not Medium Spiny Projection Neurons
《Neuroscience Bulletin》2023年第4期576-588,共13页Xuan Wang Zhenfeng Shu Quansheng He Xiaowen Zhang Luozheng Li Xiaoxue Zhang Liang Li Yujie Xiao Bo Peng Feifan Guo Da-Hui Wang Yousheng Shu 
supported by the National Natural Science Foundation of China(32130044,31630029,32171094,and 32100930);the National Key Research and Development Program of China(2021ZD0202500).
Autapses selectively form in specific cell types in many brain regions.Previous studies have also found putative autapses in principal spiny projection neurons(SPNs)in the striatum.However,it remains unclear whether t...
关键词：Asynchronous neurotransmitter release Autapse Spiny projection neuron Parvalbumin interneuron STRIATUM 
Cross‑sectional Exploration of the Relationship Between Glutamate Abnormalities and Tic Disorder Severity Using Proton Magnetic Resonance Spectroscopy
《Phenomics》2023年第2期138-147,共10页Juanjuan Hao Xin Zhang Ying Liu Zhongyang Zhang Keyu Jiang Xiao‑Yong Zhang Min Wu 
Funding This study was supported by the grant awarded by the National Natural Science Foundation of China(No.81874486,No.81873893,No.82004418);Shanghai Science and Technology Commission Research Project(No.18401902700,No.17401931200);Shanghai Municipal Health Commission(No.2018LQ010);Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX01);Zhejiang Medical Health Science and Technolog Program(No.2022RC280);Shanghai Jiaotong University School of Medicine high level local college construction project(No.18zxy006);Shaoxing University college-level research projects(No.20205038,No.2020LG1007).
Glutamate(Glu)has been reported to be closely related to the pathophysiology of Tic Disorders(TD).By using proton mag-netic resonance spectroscopy(1H-MRS),we aimed to investigate the relationship between in vivo Glu l...
关键词：Tic Disorders Magnetic resonance spectroscopy Glutamate levels STRIATUM 
The positive and negative emotion functions related to loneliness:a systematic review of behavioural and neuroimaging studies
《Psychoradiology》2023年第1期118-134,共17页Qianyi Luo Robin Shao 
supported by the National Natural Science Foundation of China (grant numbers 82371558)to R.S.
Loneliness is associated with high prevalences of major psychiatric illnesses such as major depression.However,the underlying emotional mechanisms of loneliness remained unclear.We hypothesized that loneliness origina...
关键词：LONELINESS positive emotion negative emotion emotion regulation social emotion STRIATUM prefrontal cortex 
Striatum-specific mechanisms regulate neuronal cell cycle re-entry:the choice between life and death
《Neural Regeneration Research》2023年第3期523-524,共2页Paula Dietrich Ioannis Dragatsis 
supported by genetic modulators of 3-NP neurotoxicity,No.NIH/NIEHS R21ES028429(to ID and PD)。
Mitochondria dysfunction occurs in the aging brain as well as in several neurodegenerative disorders and predisposes neuronal cells to enhanced sensitivity to neurotoxins.In particular,defects in any of the mitochondr...
关键词：SDH IMPAIRED cycle 
A novel aged mouse model of recurrent intracerebral hemorrhage in the bilateral striatum
《Neural Regeneration Research》2023年第2期344-349,共6页Li-Min Wang Zhi-Hua Liu Hong-Lei Ren Xue-Mei Chen Jun-Min Wang Hui-Min Cai Li-Ping Wei Hui-Hong Tian Jian Wang Li-Juan Wang 
supported by the Natural Science Foundation of Guangdong Province of China,No.2018A030313427;the Science and Technology Program of Guangzhou of China,No.202002030393(both to LMW)。
The current animal models of stroke primarily model a single intracerebral hemorrhage(ICH)attack,and there is a lack of a reliable model of recurrent ICH.In this study,we established 16-month-old C57 B L/6 male mouse ...
关键词：animal model cognition impairment depression-like behavior dopaminergic neurons EMOTION intracerebral hemorrhage motor neurologic function recurrent intracerebral hemorrhage 
Optimal Control of Nonlinear Systems Using Experience Inference Human-Behavior Learning
《IEEE/CAA Journal of Automatica Sinica》2023年第1期90-102,共13页Adolfo Perrusquía Weisi Guo 
supported by the Royal Academy of Engineering and the Office of the Chie Science Adviser for National Security under the UK Intelligence Community Postdoctoral Research Fellowship programme。
Safety critical control is often trained in a simulated environment to mitigate risk.Subsequent migration of the biased controller requires further adjustments.In this paper,an experience inference human-behavior lear...
关键词：Experience inference hippocampus learning system linear time-variant(LTV)systems neocortex/striatum learning systems nonlinear systems optimal control 
Long-term administration of salvianolic acid A promotes endogenous neurogenesis in ischemic stroke rats through activating Wnt3a/GSK3β/β-catenin signaling pathway被引量：4
《Acta Pharmacologica Sinica》2022年第9期2212-2225,共14页Sen Zhang De-wen Kong Guo-dong Ma Cheng-di Liu Yu-jiao Yang Shan Liu Nan Jiang Zi-rong Pan Wen Zhang Ling-lei Kong Guan-hua Du 
This work was supported by National Natural Science Foundation of China(Grant No.82004071);Beijing Municipal Natural Science Foundation(Grant No.7182113);Fundamental Research Funds for the Central Universities(Grant No.3332020038).
Stroke is the major cause of death and disability worldwide.Most stroke patients who survive in the acute phase of ischemia display various extents of neurological deficits.In order to improve the prognosis of ischemi...
关键词：ischemic stroke salvianolic acid A NEUROGENESIS Wnt3a/GSK3β/β-catenin signaling HIPPOCAMPUS STRIATUM 
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