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In ovo delivery of carvacrol triggers expression of chemotactic factors, antimicrobial peptides and pro-inflammatory pathways in the yolk sac of broiler chicken embryos
《Journal of Animal Science and Biotechnology》2025年第2期883-894,共12页Mila M.Y.Meijer Henry van den Brand Shahram Niknafs Eugeni Roura 
support by AgriFutures Australia’s Chicken Meat Program[grant number PRJ-011584]is gratefully acknowledged.
Background Broiler chickens are most vulnerable immediately after hatching due to their immature immune systems,making them susceptible to infectious diseases.The yolk plays an important role in early immune defence b...
关键词：Antimicrobial peptides Broiler chicken CARVACROL Essential oils IMMUNOMODULATION In ovo Yolk sac 
Dysfunctional glucose metabolism triggers oxidative stress to induce kidney injury in diabetes
《World Journal of Diabetes》2025年第4期19-24,共6页Meng Gao Meng-Ting Dai Guo-Hua Gong 
Supported by The Basic Research Project of Wenzhou Municipal Science and Technology Bureau,No.Y20240008;The Medical Health Science and Technology Project of Zhejiang Provincial Health Commission,No.2024KY138;The Key Laboratory of School of Laboratory Medicine and Life Sciences,Wenzhou Medical University of China,No.JS2023003。
In this editorial,we discussed the article published in the recent issue of the World Journal of Diabetes.To understand the effect of mizagliflozin on kidney injury induced by diabetes,we focused on the mechanisms by ...
关键词：Glucose metabolism Sodium-D-glucose cotransporter 1 Glucose reabsorption Mitochondrial dysfunction Reactive oxygen species Inflammation 
Esculetin triggers ferroptosis via inhibition of the Nrf2-xCT/GPx4 axis in hepatocellular carcinoma
《Chinese Journal of Natural Medicines》2025年第4期443-456,共14页Zhixin Qu Jing Zeng Laifeng Zeng Xianmei Li Fenghua Zhang 
supported by the Natural Science Foundations of Fujian Province(Nos.2021J05063 and 2023J01541);a startup grant for High-level Talents of Fujian Medical University(No.XRCZX2021014)。
Esculetin,a natural dihydroxy coumarin derived from the Chinese herbal medicine Cortex Fraxini,has demonstrated significant pharmacological activities,including anticancer properties.Ferroptosis,an iron-dependent form...
关键词：ESCULETIN Ferroptosis Hepatocellular carcinoma Nrf2-xCT/GPx4 axis ZEBRAFISH 
DNA damage triggers heritable alterations in DNA methylation patterns in Arabidopsis
《Molecular Plant》2025年第3期501-512,共12页Jinchao Li Wenjie Liang Xin-Qiang He Weiqiang Qian 
supported by the National Natural Science Foundation of China(grant no.32270288 to W.Q.;grant no.32400245 to J.L.);the China Postdoctoral Science Foundation(2024M760519 to W.L.);the Beijing Life Science Academy(2024500CA0010 to W.Q.).
It has been hypothesized that DNA damage has the potential to induce DNA hypermethylation,contributing to carcinogenesis in mammals.However,there is no sufficient evidence to support that DNA damage can cause genome-w...
关键词：DNA methylation RDDM DREAM DNA damage base excision repair 
Insulin-induced severe thyrotoxic periodic paralysis:A case report
《World Journal of Clinical Cases》2025年第7期46-51,共6页Yan-Li Wang Jian Li 
BACKGROUND Thyrotoxic periodic paralysis(TPP)is an endocrine emergency caused by thyrotoxicosis,manifesting mainly as periodic myasthenia and hypokalemia,and posing a serious threat to the patient's health.Fatigue,str...
关键词：Thyrotoxic periodic paralysis Potassium metabolism disorders INSULIN Triggers of paralysis Case report 
Elevated CXCL1 triggers dopaminergic neuronal loss in the substantia nigra of C57BL/6J mice:Evaluation of a novel Parkinsonian mouse model
《Zoological Research》2025年第1期225-235,共11页Xi-Zhen Ma Guo-Rui Jia Meng-Yu Li Sheng-Han Zhang Zhao-Xin Wang Ning Song Ying-Juan Liu Jun-Xia Xie 
supported by the National Natural Science Foundation of China (32471049,32170984,32471188,32200802);Natural Science Foundation of Shandong Province (ZR2023QH110)。
Substantial evidence points to the early onset of peripheral inflammation in the development of Parkinson's disease(PD),supporting the“body-first”hypothesis.However,there remains a notable absence of PD-specific ani...
关键词：Parkinson’s disease Mouse model CXCL1 Inflammation PPAR signaling pathway 
Author correction to“The novel ER stress inducer Sec C triggers apoptosis by sulfating ER cysteine residues and degrading YAP via ER stress in pancreatic cancer cells”[Acta Pharm Sin B 12(2022)210-227]
《Acta Pharmaceutica Sinica B》2025年第2期1208-1209,共2页Junxia Wang Minghua Chen Mengyan Wang Wenxia Zhao Conghui Zhang Xiujun Liu Meilian Cai Yuhan Qiu Tianshu Zhang Huimin Zhou Wuli Zhao Shuyi Si Rongguang Shao 
The authors regret that there was an error in the use of GAPDH image in PANC-1 cells of Fig.5B due to mistakenly pasting in the process of assembling figures.The wrong data are replaced by right ones of the same batch...
关键词：mistakenly pasting assembling figuresthe er stress yap APOPTOSIS wrong data gapdh image pancreatic cancer 
Magnaporthe oryzae infection triggers rice resistance to brown planthopper through the influence of jasmonic acid on the flavonoid biosynthesis pathway
《Insect Science》2025年第1期243-259,共17页Su Chen Zhihuan Tao Yanjie Shen Rui Yang Siyuan Yan Zixu Chen Bo Sun Xiaofang Yang 
supported by the Faculty Startup Fund for CS from Jining Medical University and by Shandong Provincial Natural Science Foundation(ZR2023QC309).
In agroecosystems,plants are constantly exposed to attack from diverse herbivorous insects and microbes,and infestation with one species may change the plant defense response to other species.In our investigation of t...
关键词：flavonoid jasmonic acid Nilaparvata lugens RICE rice blast 
A mitochondria targeting Ir(Ⅲ)complex triggers ferroptosis and autophagy for cancer therapy:A case of aggregation enhanced PDT strategy for metal complexes
《Chinese Chemical Letters》2025年第1期374-380,共7页Panpan Wang Hongbao Fang Mengmeng Wang Guandong Zhang Na Xu Yan Su Hongke Liu Zhi Su 
support from the National Natural Science Foundation of China(Nos.22277056,21977052);the Distinguished Young Scholars of Jiangsu Province(No.BK20230006);the Natural Science Foundation of Jiangsu Province(Nos.BK20230977,BK20231090);the Natural Science Foundation of the Higher Education Institutions of Jiangsu Province(No.23KJB150020);the Jiangsu Excellent Postdoctoral Program(No.2022ZB758)。
Metal complexes hold significant promise in tumor diagnosis and treatment.However,their potential applications in photodynamic therapy(PDT)are hindered by issues such as poor photostability,low yield of reactive oxyge...
关键词：Metal complex AIEgens Mitochondria targeting Enhanced photodynamic therapy Anticancer agent 
Suggested Work Modifications for Patients with Environmental and Occupational Risk Factors in Hidradenitis Suppurativa
《Occupational Diseases and Environmental Medicine》2024年第4期305-317,共13页Kelly Frasier Mary Grace Hash Alyssa Forsyth Christina Randolph Guang Orestes Raquel Batista 
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin condition characterized by painful nodules, abscesses, and scarring, primarily affecting areas rich in apocrine glands. Environmental and occupational risk...
关键词：Hidradenitis Suppurativa Occupational Risk Factors Work Environment Modifications Heat and Friction Exposure Ergonomic Adjustments Chemical Irritants Preventative Strategies Workwear for HS Environmental Triggers Dermatology and Occupational Health Collaboration 
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