supported by awards from the EPSRC Centre for Doctoral Training in Regenerative Medicine(EP/L014904/1,to JW);an NHS bursary(to RHB);an EPSRC Healthcare Technologies award(EP/T013885/1,to DMC)。
Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative therapies.Biomaterial therapies show promise as medical materials for neural repair through immunomodulation,struct...
financially supported by the National Natural Science Foundation of China,Nos.82172104(to CX),81873767(to HZ);a grant from Jiangsu Provincial Research Hospital,Nos.YJXYY202204(to HZ),YJXYY202204-ZD04(to HZ);a grant from Jiangsu Provincial Key Medical Center;Jiangsu Provincial Medical Innovation Center,No.CXZX202212;Jiangsu Provincial Medical Key Discipline,No.ZDXK202240;the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);Technology Project of Nantong,No.MS22022008(to HZ);Postgraduate Research&Practice Innovation Program of Jiangsu Province,No.SJCX21_1457(to WW)。
Demyelination and remyelination have been major focal points in the study of peripheral nerve regeneration following peripheral nerve injury.Notably,the gene regulatory network of regenerated myelin differs from that ...
National Natural Science Foundation of China(grant numbers:82100707 and 82270707);Shanghai Municipal Health Commission research project(grant number:202140191).
Objectives To evaluate the pubourethral stump angle(PUA)to determine the site of urethral transection during transperineal anastomotic urethroplasty(TAU).Patients and methods Patients diagnosed with pelvic fracture ur...
the Natural Science Foundation of Zhejiang Province(LQ22H160058).
To the Editor:Hepatocellular carcinoma(HCC)is one of the main causes of cancer related death worldwide,and new cases are expected to continue to increase in future[1].Surgical resection is still the best way to remove...
Spinal cord injury is a condition in which the parenchyma of the spinal cord is damaged by trauma or various diseases.While rapid progress has been made in regenerative medicine for spinal cord injury that was previou...
the Ethics Committee of Chinese PLA General Hospital(S2022-530-01).
Background: Creating a tunnel between the pancreas and splenic vessels followed by pancreatic parenchyma transection(“tunnel-first” strategy) has long been used in spleen-preserving distal pancreatectomy(SPDP) with ...
supported by the Health Commission of Hubei Province Medical Leading Talent Project,No.LJ20200405(to AXY)。
Neuroma formation after peripheral nerve transection often leads to severe neuropathic pain.Regenerative peripheral nerve interface has been shown to reduce painful neuroma in the clinic.However,no reports have invest...
supported by the National Natural Science Foundation of China,Nos.81620108008(to YQL),31971112(to YQL),82071373(to JC);Innovation Capability Support Program of Shaanxi,No.2021TD-57(to YQL)。
A hyaluronic acid granular hydrogel can promote neuronal and astrocyte colony formation and axonal extension in vitro,suggesting that the hydrogel can simulate an extracellular matrix structure to promote neural regen...
supported by the National Natural Science Foundation of China,No.81801787(to XZS);China Postdoctoral Science Foundation,No.2018M640238(to XZS);the Natural Science Foundation of Tianjin,No.20JCQNJC01690(to XLC)。
Percutaneous electrical nerve stimulation of an injured nerve can promote and accelerate peripheral nerve regeneration and improve function.When performing acupuncture and moxibustion,locating the injured nerve using ...
supported by grants from the National Institutes of Health,USA(No.K08 AR060164-01A);Department of Defense,USA(Nos.W81XWH-16-1-0725 and W81XWH-19-1-0773)in addition to institutional support from the Pennsylvania State University College of Medicine。
We recently demonstrated a repurposing beneficial effect of 4-aminopyridine(4-AP),a potassium channel blocker,on functional recove ry and muscle atrophy after sciatic nerve crush injury in rodents.However,this effect ...