云南高校图书馆联盟文献共享服务平台- 4-AMINOPYRIDINE

4-AMINOPYRIDINE: 作品数：10被引量：11H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：周鹏王立中杨新春刘秀兰常昆更多>>; 相关机构：中国工程物理研究院首都医科大学普渡大学中国科学院更多>>; 相关期刊：《Acta Pharmacologica Sinica》《Science China Chemistry》《Chinese Medical Journal》《Neural Regeneration Research》更多>>; 相关基金：河南省自然科学基金国家自然科学基金更多>>

Supramolecular assemblies of cucurbit[n]urils and 4-aminopyridine controlled by cucurbit[n]uril size(n=5,6,7 and 8): 《Chinese Chemical Letters》2023年第7期131-136,共6页Yun Lu Zhichao Yu Xinan Yang Jingjing Dai Peihui Shan Xianhao Feng Zhu Tao Carl Redshaw Xin Xiao; supported by the Innovation Program for Highlevel Talents of Guizhou Province (No. 2016-5657);the University of Hull for support。; The binding interactions between 4-aminopyridine(4-AP) and a series of cucurbit[n]urils(Q[5], Q[6],TMe Q[6], Q[7], Q[8]) have been studied using1H NMR spectroscopy, UV–vis absorption spectroscopy,isothermal titration...; 关键词：Cucurbit[n]urils 4-AMINOPYRIDINE Host-guest chemistry Supramolecular assembly Exo binding

Functional recovery and muscle atrophy in pre-clinical models of peripheral nerve transection and gap-grafting in mice:effects of 4-aminopyridine: 《Neural Regeneration Research》2023年第2期439-444,共6页Jung Il Lee M A Hassan Talukder Zara Karuman Anagha A.Gurjar Prem Kumar Govindappa Jagadeeshaprasad M.Guddadarangaiah Kristen M.Manto Grant D.Wandling John P.Hegarty David L.Waning John C.Elfar; supported by grants from the National Institutes of Health,USA(No.K08 AR060164-01A);Department of Defense,USA(Nos.W81XWH-16-1-0725 and W81XWH-19-1-0773)in addition to institutional support from the Pennsylvania State University College of Medicine。; We recently demonstrated a repurposing beneficial effect of 4-aminopyridine(4-AP),a potassium channel blocker,on functional recove ry and muscle atrophy after sciatic nerve crush injury in rodents.However,this effect ...; 关键词：4-AMINOPYRIDINE functional recovery muscle atrophy nerve gap nerve grafting nerve imaging nerve transection

Corrigendum: Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice: 《Neural Regeneration Research》2021年第3期549-549,共1页; In the article titled“Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice”,published on pages 136–144,Issue 1,Vol...; 关键词：REGENERATION improve CRUSH

Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice被引量：1: 《Neural Regeneration Research》2020年第11期2098-2107,共10页Chia George Hsu M A Hassan Talukder Li Yue Loel CTurpin Mark Noble John C.Elfar; supported by grants from the National Institutes of Health(NIH;K08 AR060164-01A);the Department of Defense(DoD;W81XWH-16-1-0725)to JCE;institutional support from the University of Rochester and Pennsylvania State University Medical Centers。; 4-Aminopyridine(4-AP), an FDA-approved drug for the symptomatic treatment of multiple sclerosis, is used to improve neuromuscular function in patients with diverse demyelinating disorders. We recently demonstrated tha...; 关键词：4-AMINOPYRIDINE electron microscopy of nerves functional recovery gene expression MUSCLE force MUSCLE mass ORAL administration pharmacokinetics SCIATIC NERVE crush INJURY SCIATIC NERVE denervation INJURY

Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice被引量：3: 《Neural Regeneration Research》2020年第1期136-144,共9页Andrew RClark Chia George Hsu M A Hassan Talukder Mark Noble John CElfar; supported by grants from the National Institutes of Health(K08 AR060164-01A);Department of Defense(W81XWH-16-1-0725)to JCE in addition to institutional support from the University of Rochester and Pennsylvania State University Medical Centers; Oral 4-aminopyridine(4-AP)is clinically used for symptomatic relief in multiple sclerosis and we recently demonstrated that systemic 4-AP had previously unknown clinically-relevant effects after traumatic peripheral n...; 关键词：4-AMINOPYRIDINE electron microscopy functional recovery NERVE conduction velocity PERIPHERAL NERVE injury PHARMACOKINETICS TRANSDERMAL administration

Potassium channel blockers as an effective treatment to restore impulse conduction in injured axons: 《Neuroscience Bulletin》2011年第1期36-44,共9页史日异孙文婧; supported by the Purdue Research Foundation(No. 61133);National Institute of Health,USA(No.1R21 NS050174-01A1); Most axons in the vertebral central nervous system are myelinated by oligodendrocytes.Myelin protects and insulates neuronal processes,enabling the fast,saltatory conduction unique to myelinated axons.Myelin disruptio...; 关键词：AXON conduction potassium channel injury DEMYELINATION 4-AMINOPYRIDINE

Simultaneous determination of nitrophenol isomers at the single-wall carbon nanotube compound conducting polymer film modified electrode被引量：4: 《Science China Chemistry》2005年第3期177-182,共6页ZHANG Hui WANG Zhenhui ZHOU Shuping; the Natural Science Foundation of Henan Province,China(Grant No.0311021000);the Key Laboratory of Environmental Science and Engineering,Education Commission of Henan Province.; Based on the molecular recognition ability of conductive polymer and the peculiar properties of carbon nanotubes,a novel single wall nanotubes(SWNTs)compound poly(4-aminopyridine)modified electrode(SWNTs/POAPE)is prep...; 关键词：carbon nanotube compound poly(4-aminopyridine) modified electrode NITROPHENOL ISOMER voltammetry.

Recording of spared motor evoked potentials and its augmentation by 4-aminopyridine in chronic spinal cord-injured rats: 《Chinese Medical Journal》2001年第2期43-49,106-107,共9页余科炜李家顺戎伟芳贾连顺袁文叶晓健石志才戴伯军; thegrantsfromtheAdvanceDepartment FoundationfromtheMedicalMinistryofShanghai China! (No 1995 Ⅲ 0 0 8); Objective　To research the direct electrophysiological evidence of discomplete spinal cord injury (SCI) and the effect of 4-aminopyridine on it.Methods　Motor evoked potentials (MEPs), both spinal cord recorded MEPs (...; 关键词：motor evoked potential · microelectrode · discomplete spinal cord injury · 4 aminopyridine · rat

Stimulatory effect of trans-cinnamaldehyde on norepinephrine secretion in cultured pheochromocytoma (PC-12) cells被引量：3: 《Acta Pharmacologica Sinica》2000年第12期119-123,共5页TSAI Chin-Chuan; AIM: The effect of trans-cinnamaldehyde (CNMA) on the release of norepinephrine (NE) from nerve terminal was investigated using rat pheochromocytoma 12 (PC-12) cells. METHODS: The amount of NA released from PC-12 cell...; 关键词：PC12 CELLS CINNAMALDEHYDE bisox-onol SAXITOXIN 4-AMINOPYRIDINE NOREPINEPHRINE

Tetraethylammonium and 4-aminopyridine enhancement of 5-HT_3 receptor-mediated contraction of guinea pig ileum in vitro: 《中国药理学报》1998年第5期451-455,共5页袁玉民杨惠华胡国渊; 目的：研究四乙铵（ＴＥＡ）、４氨基吡啶（４ＡＰ）对５ＨＴ３受体介导的豚鼠回肠收缩的影响．方法：等长换能器记录回肠收缩；［３Ｈ］ＧＲ６５６３０结合试验测定５ＨＴ３受体结合特性．结果：ＴＥＡ、４ＡＰ引起回肠收缩...; 关键词：受体四乙铵氨基吡啶回肠收缩肠肌丛 5-HT3

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