supported by the National Natural Science Foundation of China(32001679 and 31871801);the Science and Technology Research of Shaanxi Province(2021QFY07-03);supported by the Fundamental Research Funds for the Central Universities(GK202103098);the Scientific and Technological Achievements Commercialization Program of Shaanxi(2023-YDCGZH-13)。
Gut microbiota regulate the activation of adipose browning,which promote energy dissipation and combat diet-induced obesity.Pomegranate peel polyphenols(PPPs)have been shown to reduce obesity,regulate lipid metabolism...
supported in part by the National Natural Science Foundation of China (No.82173134);the Chongqing Fund for Outstanding Youth (China) (No.CSTB2022NSCO-JOX0010).
The tumor microenvironment is a complex environment comprising tumor cells,non-tumor cells,and other critical non-cellular components.Some studies about tumor micro-environment have recently achieved remarkable progre...
supported by the Natural Science Foundation of Sichuan Province(No.2022NSFSC0720);Research Center for the Development of the Comprehensive Health Industry and Rural Revitalization of Sichuan TCM(No.DJKYB202306);State Administration of Traditional Chinese Medicine of Sichuan Province of China(No.2020HJZX001).
Obesity has become a global threat to health;however,the available drugs for treating obesity are limited.We investigated the anti-obesity effect of hydroxy-α-sanshool(HAS),an amide derived from the fruit of Zanthoxy...
Increasing evidence of the significant clinical value of protection against ischemia/reperfusion injury has contributed to the realization of the independent importance of this approach in improving prognosis and redu...
supported by the CAMS Initiative for Innovative Medicine(2022-I2M-1-012);the 111 Project(B18007);National Key R&D Program of China(2020YFA0113000);Key-Area Research and Development Program of Guangdong Province(2021B0909060001);2021 General Research Institute for Nonferrous Metals‘Unveiling and Commanding’Project(2021JC0103).
UVB radiation induces oxidative stress,DNA damage,and inflammation,leading to skin wrinkling,compromised barrier function,and an increased risk of carcinogenesis.Addressing or preventing photoaging may offer a promisi...
National Key Research and Development Program of China(Nos.2020YFA0803801,2022YFA0806400,and 2018YFA0800701);National Natural Science Foundation of China(Nos.81921001 and 32200949);project funded by China Postdoctoral Science Foundation(BX20220021,China);Xin Du and Julian Heng(Remotely Consulting,Australia)provided professional English-language editing of this article(Certificate No.2Tv2Ry7I).
The adipose tissue of mammals represents an important energy-storing and endocrine organ, and its dysfunction is relevant to the onset of several health problems, including non-alcoholic fatty liver disease (NAFLD). H...
Parkinson’s disease(PD)is one of the fastest-growing neurodegenerative disorders worldwide.So far,PD treatments only offer little clinical relief and cannot reverse or stop the disease progression.Stem cell(SC)therap...
supported by grants from the CAMS Innovation Fund for Medical Sciences(2021-I2M-1-052);Tianjin Natural Science Foundation for Jingjinji Collaboration(23JCZXJC00240);Capital's Funds for Health Improvement and Research(CFH:2022-2-5072);Tianjin Hospital Fund for Science and Technology(Tjyy2109);the Open Fund of Tianjin Key Laboratory of Biomedical Materials(2022BMEKFKT002)。
Background:In facial plastic surgery,patients with nasal deformity are often treated by rib cartilage transplantation.In recent years,cartilage tissue engineering has developed as an alternative to complex surgery for...
Objective To establish a body composition analysis system based on chest CT,and to observe its value for evaluating content of chest muscle and adipose.Methods T7—T8 layer CT images of 108 pneumonia patients were col...
supported by the Japan Society for the Promotion of Science (JSPS)Grant-in-Aid for Scientific Research (B) (22H03157 to L.L.and J.L.);supported by Otsuka Toshimi Scholarship Foundation.
Human-induced pluripotent stem cell-derived cardiomyocytes(hiPSC-CMs)have been widely used in therapy of ischemic heart disease.However,there are still remaining issues that limit the therapeutic efficacy,such as immu...