ADIPOSE

作品数:265被引量:922H指数:17
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相关领域:医药卫生更多>>
相关作者:周红文马超谭谦陈海华霍然更多>>
相关机构:华中农业大学北京大学山东大学南京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金中国博士后科学基金更多>>
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Pomegranate peel polyphenols improves diet-induced obesity and promotes adipose browning development through gut microbiota in mice
《Food Science and Human Wellness》2025年第2期605-616,共12页Zhuoting Luo Xiaoyu Song Mengting Li Jianke Li Chen Hou 
supported by the National Natural Science Foundation of China(32001679 and 31871801);the Science and Technology Research of Shaanxi Province(2021QFY07-03);supported by the Fundamental Research Funds for the Central Universities(GK202103098);the Scientific and Technological Achievements Commercialization Program of Shaanxi(2023-YDCGZH-13)。
Gut microbiota regulate the activation of adipose browning,which promote energy dissipation and combat diet-induced obesity.Pomegranate peel polyphenols(PPPs)have been shown to reduce obesity,regulate lipid metabolism...
关键词:Pomegranate peel polyphenols OBESITY Gut microbiota High-fat diet Adipose browning 
Involvement of the ubiquitin-proteasome system in the regulation of the tumor microenvironment and progression
《Genes & Diseases》2025年第2期227-243,共17页Yulan Huangg Yuan Gao Zhenghong Lin Hongming Miao 
supported in part by the National Natural Science Foundation of China (No.82173134);the Chongqing Fund for Outstanding Youth (China) (No.CSTB2022NSCO-JOX0010).
The tumor microenvironment is a complex environment comprising tumor cells,non-tumor cells,and other critical non-cellular components.Some studies about tumor micro-environment have recently achieved remarkable progre...
关键词:Adipose cells DEUBIQUITINATION IMMUNITY Tumor microenvironment Tumor-associated fibroblasts UBIQUITINATION 
Hydroxy-α-sanshool-loaded adipose-targeted mesoporous silica nanoparticles induce white adipose browning and reduce obesity by activating TRPV1
《Bio-Design and Manufacturing》2025年第2期288-309,I0005-I0011,共29页Qing Zhang Chengxun He Juan Guo Dandan Tang Die Qian Chuan Zheng Chunjie Wu Wei Peng 
supported by the Natural Science Foundation of Sichuan Province(No.2022NSFSC0720);Research Center for the Development of the Comprehensive Health Industry and Rural Revitalization of Sichuan TCM(No.DJKYB202306);State Administration of Traditional Chinese Medicine of Sichuan Province of China(No.2020HJZX001).
Obesity has become a global threat to health;however,the available drugs for treating obesity are limited.We investigated the anti-obesity effect of hydroxy-α-sanshool(HAS),an amide derived from the fruit of Zanthoxy...
关键词:Hydroxy-α-sanshool Adipocyte targetability Mesoporous silica nanoparticles White adipose tissue browning OBESITY 
Protective activity of adipose-derived stem cell extracellular vesicles in ischemia and/or reperfusion
《World Journal of Stem Cells》2025年第1期1-5,共5页Alexander E Berezin 
Increasing evidence of the significant clinical value of protection against ischemia/reperfusion injury has contributed to the realization of the independent importance of this approach in improving prognosis and redu...
关键词:Extracellular vesicles Adipose mesenchymal stem cells MicroRNA-21-5p Cardiac protection ISCHEMIA REPERFUSION 
Human adipose and umbilical cord mesenchymal stem cellderived extracellular vesicles mitigate photoaging via TIMP1/Notch1
《Signal Transduction and Targeted Therapy》2024年第11期5319-5335,共17页Huan Zhang Xian Xiao Liping Wang Xianhao Shi Nan Fu Shihua Wang Robert Chunhua Zhao 
supported by the CAMS Initiative for Innovative Medicine(2022-I2M-1-012);the 111 Project(B18007);National Key R&D Program of China(2020YFA0113000);Key-Area Research and Development Program of Guangdong Province(2021B0909060001);2021 General Research Institute for Nonferrous Metals‘Unveiling and Commanding’Project(2021JC0103).
UVB radiation induces oxidative stress,DNA damage,and inflammation,leading to skin wrinkling,compromised barrier function,and an increased risk of carcinogenesis.Addressing or preventing photoaging may offer a promisi...
关键词:NOTCH1 INFLAMMATION alterations 
Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
《Acta Pharmaceutica Sinica B》2024年第11期4883-4898,共16页Pengcheng Wang Song-Yang Zhang YongQiang Dong Guangyi Zeng Huiying Liu Xian Wang Changtao Jiang Yin Li 
National Key Research and Development Program of China(Nos.2020YFA0803801,2022YFA0806400,and 2018YFA0800701);National Natural Science Foundation of China(Nos.81921001 and 32200949);project funded by China Postdoctoral Science Foundation(BX20220021,China);Xin Du and Julian Heng(Remotely Consulting,Australia)provided professional English-language editing of this article(Certificate No.2Tv2Ry7I).
The adipose tissue of mammals represents an important energy-storing and endocrine organ, and its dysfunction is relevant to the onset of several health problems, including non-alcoholic fatty liver disease (NAFLD). H...
关键词:Non-alcoholicfatty liver disease Adiposetissue Lipid metabolism Adrenomedullin 2 CERAMIDE HIF2α ACER2 
Pioneering a new era in Parkinson’s disease management through adipose-derived mesenchymal stem cell therapy
《BIOCELL》2024年第10期1419-1428,共10页MOHAMMAD-SADEGH LOTFI FATEMEH B.RASSOULI 
Parkinson’s disease(PD)is one of the fastest-growing neurodegenerative disorders worldwide.So far,PD treatments only offer little clinical relief and cannot reverse or stop the disease progression.Stem cell(SC)therap...
关键词:Parkinson’s disease Adipose derived-mesenchymal stem cells Cell therapy Dopaminergic neurons 
Adipose-derived mesenchymal stem cell-incorporated PLLA porous microspheres for cartilage regeneration
《Animal Models and Experimental Medicine》2024年第5期685-695,共11页Chang Gao Wenlong Yuan Dongcheng Wang Xin Zhang Tong Zhang Zhimin Zhou 
supported by grants from the CAMS Innovation Fund for Medical Sciences(2021-I2M-1-052);Tianjin Natural Science Foundation for Jingjinji Collaboration(23JCZXJC00240);Capital's Funds for Health Improvement and Research(CFH:2022-2-5072);Tianjin Hospital Fund for Science and Technology(Tjyy2109);the Open Fund of Tianjin Key Laboratory of Biomedical Materials(2022BMEKFKT002)。
Background:In facial plastic surgery,patients with nasal deformity are often treated by rib cartilage transplantation.In recent years,cartilage tissue engineering has developed as an alternative to complex surgery for...
关键词:centrifugation perfusion CHONDROGENESIS hyaluronic acid nasal fillers PLLA porous microspheres 
Automated body composition analysis system based on chest CT for evaluating content of muscle and adipose
《中国医学影像技术》2024年第8期1242-1248,共7页YANG Jie LIU Yanli CHEN Xiaoyan CHEN Tianle LIU Qi 
自贡市市级科技计划项目(2021YXY12)。
Objective To establish a body composition analysis system based on chest CT,and to observe its value for evaluating content of chest muscle and adipose.Methods T7—T8 layer CT images of 108 pneumonia patients were col...
关键词:body composition THORAX muscle skeletal adipose tissue deep learning tomography X-ray computed 
Development of composite functional tissue sheets using hiPSC-CMs and hADSCs to improve the cardiac function after myocardial infarction
《Bioactive Materials》2024年第7期533-548,共16页Jingbo Zhang Junjun Li Xiang Qu Yuting Liu Lifu Sun Akima Harada Ying Hua Nagako Sougawa Akiko Tabata Li Liu Shigeru Miyagawa 
supported by the Japan Society for the Promotion of Science (JSPS)Grant-in-Aid for Scientific Research (B) (22H03157 to L.L.and J.L.);supported by Otsuka Toshimi Scholarship Foundation.
Human-induced pluripotent stem cell-derived cardiomyocytes(hiPSC-CMs)have been widely used in therapy of ischemic heart disease.However,there are still remaining issues that limit the therapeutic efficacy,such as immu...
关键词:Human induced pluripotent stem cell-derived cardiomyocyte Human adipose-derived mesenchymal stem cell Tissue engineering Myocardial infarction Regenerative medicine 
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