云南高校图书馆联盟文献共享服务平台- CERAMIDE

CERAMIDE: 作品数：96被引量：228H指数：7; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：侯琦王红金鑫宋智琦肖汀更多>>; 相关机构：复旦大学台北医学大学北京大学中国科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金重庆市自然科学基金更多>>

Emerging roles of the acid sphingomyelinase/ceramide pathway in metabolic and cardiovascular diseases:Mechanistic insights and therapeutic implications: 《World Journal of Cardiology》2025年第2期9-21,共13页Hong-Ni Wang Ye Wang Si-Yao Zhang Lan Bai; Supported by Ganzhou City’s“Light of the Soviet Area”Talent Project,No.GZSQZG202301009。; Metabolic diseases have emerged as a leading cause of mortality from non-communicable diseases,posing a significant global public health challenge.Al-though the association between ceramides(Cers)and metabolic disease...; 关键词：Acid sphingomyelinase CERAMIDE Metabolic and cardiovascular diseases Glycolipid metabolism Inflammation Mitochondrial homeostasis

Neurotensin-neurotensin receptor 2 signaling in adipocytes suppresses food intake through regulating ceramide metabolism: 《Cell Research》2025年第2期117-131,共15页Wei Fu Yuanting Lai Kexin Li Yue Yang Xiao Guo Qifan Gong Xiaofeng Zhou Liying Zhou Cenxi Liu Zhi Zhang Jisun So Yufeng Zhang Lin Huang Guangxing Lu Chuanyou Yi Qichu Wang Chenyu Fan Chao Liu Jiaxing Wang Haiyi Yu Yimin Zhao Tao Huang Hyun Cheol Roh Tiemin Liu Huiru Tang Jianping Qi Ming Xu Yan Zheng He Huang Jin Li; supported by the National Key R&D Program of China from Ministry of Science&Technology(2020YFA0803800,2019YFA0801900,NSFC92057115);Shanghai Sailing Program 20YF1402600 to H.H.,the National Key R&D Program of China from Ministry of Science&Technology(2020YFA0803600,2018YFA0801300,2023YFA1801000 to J.L.);the National Natural Science Foundation of China(32071138 and 32371193 to J.L.),and SKLGE-2118 to J.L.; Neurotensin(NTS)is a secretory peptide produced by lymphatic endothelial cells.Our previous study revealed that NTS suppressed the activity of brown adipose tissue via interactions with NTSR2.In the current study,we f...; 关键词：INTAKE METABOLISM Together

α-Galactosylceramide modulates the brain's inflammatory microenvironment to counteract learning and memory dysfunction in Aβ_(1–42)model mice: 《Journal of Chinese Pharmaceutical Sciences》2024年第12期1110-1117,共8页Guangchan Jing Jingting Kang Chao Ji; National Natural Science Foundation of China(Grant No.81100801)。; Alzheimer's disease(AD)is the most prevalent neurodegenerative disorder affecting the elderly.Among its pathological mechanisms,neuroinflammation triggered by amyloid-β(Aβ)aggregation is considered a key contributor...; 关键词：Alzheimer’s disease Α-GALCER M2 microglia/macrophage NEUROINFLAMMATION Microglial polarization

Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism: 《Acta Pharmaceutica Sinica B》2024年第11期4883-4898,共16页Pengcheng Wang Song-Yang Zhang YongQiang Dong Guangyi Zeng Huiying Liu Xian Wang Changtao Jiang Yin Li; National Key Research and Development Program of China(Nos.2020YFA0803801,2022YFA0806400,and 2018YFA0800701);National Natural Science Foundation of China(Nos.81921001 and 32200949);project funded by China Postdoctoral Science Foundation(BX20220021,China);Xin Du and Julian Heng(Remotely Consulting,Australia)provided professional English-language editing of this article(Certificate No.2Tv2Ry7I).; The adipose tissue of mammals represents an important energy-storing and endocrine organ, and its dysfunction is relevant to the onset of several health problems, including non-alcoholic fatty liver disease (NAFLD). H...; 关键词：Non-alcoholicfatty liver disease Adiposetissue Lipid metabolism Adrenomedullin 2 CERAMIDE HIF2α ACER2

High temperature ameliorates high-fat diet-induced obesity by promoting ceramide breakdown in skeletal muscle tissue: 《Life Metabolism》2024年第5期1-16,共16页Qiankun Wang Lupeng Chen Junzhi Zhang Yue Liu Yi Jin Jian Wu Zhuqing Ren; supported by the National Natural Science Foundation of China(32172700);the Fundamental Research Funds for the Central Universities(2662023DKPY003 and 2662022DKPY002).; Obesity is considered an epidemic often accompanied by insulin resistance(IR).Heat treatment(HT)has been shown to prevent high-fat diet-induced IR in skeletal muscle,but the underlying mechanisms are poorly understood...; 关键词：high temperature OBESITY insulin resistance ceramide breakdown lipid droplets

Evaluating the effect of moisturizers containing endogenous lipids on skin barrier properties: 《Journal of Dermatologic Science and Cosmetic Technology》2024年第3期14-19,共6页Yucong Wang Shuting Li Yunfei Ai Stephen Lynch Nada Baalbaki Xianghua Zhang Xiaofeng He Xiaoqing Huang Andrew Steel Kungchi Hsu Hequn Wang; Lipids in stratum corneum are largely responsible for skin barrier function.There have been numerous studies on skin barrier repairing and moisturizing effects of products containing occlusives,emollients and humectan...; 关键词：SKIN BARRIER CERAMIDE

Linking IL-10 signaling with lipid metabolic programs in macrophages:dysregulated ceramide homeostasis drives colitis被引量：1: 《Signal Transduction and Targeted Therapy》2024年第7期2835-2836,共2页Imke Atreya Markus F.Neurath; supported by the following grants from the DFG;German Research Foundation:TRR241(project number 375876048);AT 122/2-1(project number 511510453);supported by the Interdisciplinary Center for Clinical Research Erlangen:IZKF D37.; In a recent study published in Nature,York and coworkers identified the immunometabolic regulation of mono-unsaturated fatty acid(MUFA)pools and the subsequent increase in sphingolipid biosynthesis in TLR2-activated m...; 关键词：HOMEOSTASIS IMPAIRED INTESTINE

Study on the interaction between volatile oil components and skin lipids based on molecular docking techniques: 《Digital Chinese Medicine》2024年第2期148-159,共12页REN Weishuo WULAN Tuya DAI Xingxing ZHANG Yingying JIA Mingyue FENG Minfang SHI Xinyuan; National Science Foundation of China(82174093);Fundamental Research Funds for the Central Universities(BUCM-2019-JYB-JS-016).; Objective To analyze the interactions between different structural types of volatile oil compo-nents(VOCs)and skin lipid molecules;and investigate the mechanism of volatile oil in Chi-nese materia medica(VOCMM)as pene...; 关键词：Chinese materia medica Volatile oil Stratum corneum lipids Transdermal penetration-enhancing effects Molecular docking Ceramide 2(CER2) Penetration enhancers

Cyanidin-3-glucoside protects the photooxidative damage of retinal pigment epithelium cells by regulating sphingolipid signaling and inhibiting MAPK pathway被引量：2: 《Food Science and Human Wellness》2024年第2期621-632,共12页Tingting Liu Wentao Qi Wenting Peng Jianan Zhang Yong Wang; funded by the National Natural Science Foundation of China(31901698);Young Elite Scientists Sponsorship Program by the China Association for Science and Technology(2019QNRC001)。; Cyanidin-3-glucoside(C3G)is the most common anthocyanin in dark grains and berries and is a food functional factor to improve visual health.However,the mechanisms of C3G on blue light-induced retinal pigment epithelia...; 关键词：Cyanidin-3-glucoside CERAMIDE MAPK pathway Mitochondria-dependent apoptosis Lipidomics analysis

The Effect of a Novel Complex, Composed of Ceramide, Energizing Peptide and Camu Camu Extract, on Epidermal Barrier Function and Dermal Antiaging Properties in Ex Vivo Human Skin Small Live Cohort: 《Journal of Cosmetics, Dermatological Sciences and Applications》2024年第1期1-11,共11页Landau Marina Landau-Blum Shir Samuel Kassirer Audrey Le Mestr Armelle Perrin Julien Verdon Laurine Bergeron Corinne Morel Isabelle Imbert; The skin’s primary function is to protect the body against a spectrum of environmental stressors, including mechanical insults, microorganisms, chemicals, and allergens. Located in the outermost layers, the primary s...; 关键词：SUPCERATTM Complex Epidermal Skin Barrier Moisturization ANTIAGING CERAMIDE Camu Camu Extract

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