supported by the National Natural Science Foundation of China,Nos.82171456(to QY)and 81971229(to QY);the Natural Science Foundation of Chongqing,Nos.CSTC2021JCYJ-MSXMX0263(to QY)and CSTB2023NSCQ-MSX1015(to XL);Doctoral Innovation Project of The First Affiliated Hospital of Chongqing Medical University,Nos.CYYY-BSYJSCXXM-202318(to JW)and CYYY-BSYJSCXXM-202327(to HT).
Recent studies have shown that fibrotic scar formation following cerebral ischemic injury has varying effects depending on the microenvironment.However,little is known about how fibrosis is induced and regulated after...
partially supported by the State Funding Agency of Minas Gerais,Brazil(FAPEMIG),Process No.APQ-01811-21;supported by Alexander von Humboldt-Stiftung(AvH)/Coordena??o de Aperfei?oamento de Pessoal de Nível Superior(CAPES);National Council for Scientific and Technological Development-CNPq(Process No.308138/2022-8);supported by National Council for Scientific and Technological Development-CNPq(Process No.BPD-00905-22).
Background:Ischemic preconditioning(IPC)is purported to have beneficial effects on athletic performance,although findings are inconsistent,with some studies reporting placebo effects.The majority of studies have inves...
supported by the National Key Research and Development Program of China (No.2021YFA1100503);Zhejiang Provincial Natural Science Foundation (China) (No.LY22H160048);Key Research&Development Program of Zhejiang Province (China) (No.2022C03108).
Hepatic steatosis is prevalent worldwide and is characterized as excessive lipid accumulation with/without inflammation and injury in the liver.Hepatic ischemia-reperfusion(HIR)injury commonly occurs in the process of...
supported by the National Science Foundation of China(No.81903832),the Key Research and Development Plan of Shaanxi Province(No.2022SF-182),the Fundamental Research Funds for the Central Universities(No.D5000210799);Shaanxi Provincial Traditional Chinese Medicine Administration"Double Chain Integration"Middle Youth Research and Innovation Team Project(No.2022-SLRH-LJ-007);Shanghai Science and Technology Innovation Action Plan(No.22S21902600).
Aralia taibaiensi,widely distributed in western China,particularly in the Qinba Mountains,has been utilized as a folk medicine for treating diabetes,gastropathy,rheumatism,and cardiovascular diseases.Saponins from A.t...
BACKGROUND The association between uric acid-albumin ratio(UAR)with different diseases has been evaluated before.However,the association between UAR with spontaneous reperfusion(SR)in patients with ST-segment elevatio...
Post-reperfusion syndrome(PRS)in liver transplant recipients remains one of the most dreaded complications in liver transplant surgery.PRS can impact the short-term and long-term patient and graft outcomes.The definit...
supported by the National Natural Science Foundation of China(NSFC)(No.82360065 and No.81760047).
Objective Atrial natriuretic peptide(ANP)and Zn^(2+)have been shown to confer cardioprotection against ischemia/reperfu-sion(I/R)injury.Zn^(2+)alleviates myocardial hypertrophy and pulmonary hypertension by regulating...
Increasing evidence of the significant clinical value of protection against ischemia/reperfusion injury has contributed to the realization of the independent importance of this approach in improving prognosis and redu...
supported by the National Natural Science Foundation of China(81671228,32321004,92057202,92357308);the Ministry of Science and Technology of China(2021ZD0201702);Joint project of Chongqing Health Commission and Science and Technology Bureau(2023GGXM003);the National Key Research and Development Program of China(2018YFA0800901)。
Constituting 6.5%to 19.6%of all stroke cases worldwide,non-traumatic intracerebral hemorrhage(ICH)represents the most devastating form of stroke,with aging,male gender,and hypertension being important risk factors tha...
upported by the National Key Research and Development Program of China (No.2021YFC2500100);1.3.5 Project for Disciplines of Excellence of West China Hospital of Sichuan University (No.ZYYC23016);the Key Research Projects of Sichuan Province,China (No.24SYSX0093);Major Science&Technology Program of Sichuan Province,China (No.2022ZDZX0021);the National Clinical Research Center for Geriatrics,West China Hospital,Sichuan University (China) (No.Z2023LC005);the Natural Science Foundation of Sichuan Province,China (No.2022NSFSC1509);the Fundamental Research Funds for the Central Universities (China) (No.2023SCU12074).
Programmed cell death contributes to neurological damage in ischemic stroke,especially during the reperfusion stage.Several cell death pathways have been tested preclinically and clinically,including ferroptosis,necro...