REPERFUSION

作品数:484被引量:2401H指数:23
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Fibrotic scar formation after cerebral ischemic stroke:Targeting the Sonic hedgehog signaling pathway for scar reduction
《Neural Regeneration Research》2026年第2期756-768,共13页un Wen Hao Tang Mingfen Tian Ling Wang Qinghuan Yang Yong Zhao Xuemei Li Yu Ren Jiani Wang Li Zhou Yongjun Tan Haiyun Wu Xinrui Cai Yilin Wang Hui Cao Jianfeng Xu Qin Yang 
supported by the National Natural Science Foundation of China,Nos.82171456(to QY)and 81971229(to QY);the Natural Science Foundation of Chongqing,Nos.CSTC2021JCYJ-MSXMX0263(to QY)and CSTB2023NSCQ-MSX1015(to XL);Doctoral Innovation Project of The First Affiliated Hospital of Chongqing Medical University,Nos.CYYY-BSYJSCXXM-202318(to JW)and CYYY-BSYJSCXXM-202327(to HT).
Recent studies have shown that fibrotic scar formation following cerebral ischemic injury has varying effects depending on the microenvironment.However,little is known about how fibrosis is induced and regulated after...
关键词:central nervous system FIBROBLASTS fibrosis ischemic stroke Mitofusin 2 middle cerebral artery occlusion/reperfusion P-Smad3 Sonic Hedgehog SMAD3 TOM20 
Does ischemic preconditioning enhance sports performance more than placebo or no intervention?A systematic review with meta-analysis
《Journal of Sport and Health Science》2025年第2期21-34,共14页Hiago L.R.Souza Géssyca T.Oliveira Anderson Meireles Marcelo P.dos Santos Joao G.Vieira Rhai A.Arriel Stephen D.Patterson Moacir Marocolo 
partially supported by the State Funding Agency of Minas Gerais,Brazil(FAPEMIG),Process No.APQ-01811-21;supported by Alexander von Humboldt-Stiftung(AvH)/Coordena??o de Aperfei?oamento de Pessoal de Nível Superior(CAPES);National Council for Scientific and Technological Development-CNPq(Process No.308138/2022-8);supported by National Council for Scientific and Technological Development-CNPq(Process No.BPD-00905-22).
Background:Ischemic preconditioning(IPC)is purported to have beneficial effects on athletic performance,although findings are inconsistent,with some studies reporting placebo effects.The majority of studies have inves...
关键词:DECEPTION Nocebo effects Athletic performance REPERFUSION TOURNIQUETS 
Human amniotic epithelial cells alleviate ischemia-reperfusion injury of steatotic livers through mediating PAK1/AMPK-dependent autophagy
《Genes & Diseases》2025年第2期110-112,共3页Xun Qiu Hanzhi Xu Yawen Tan Jinying Li Zhoucheng Wang Zhengxing Lian Xuyong Wei Luyang Yu Kai Wang Xiao Xu 
supported by the National Key Research and Development Program of China (No.2021YFA1100503);Zhejiang Provincial Natural Science Foundation (China) (No.LY22H160048);Key Research&Development Program of Zhejiang Province (China) (No.2022C03108).
Hepatic steatosis is prevalent worldwide and is characterized as excessive lipid accumulation with/without inflammation and injury in the liver.Hepatic ischemia-reperfusion(HIR)injury commonly occurs in the process of...
关键词:ischemia REPERFUSION Hepatic 
Saponins from Aralia taibaiensis protect against brain ischemia/reperfusion injuries by regulating the apelin/AMPK pathway
《Chinese Journal of Natural Medicines》2025年第3期299-310,共12页Zhengrong Li Yuwen Liu Kedi Liu Xingru Tao Naping Hu Wangting Li Jialin Duan 
supported by the National Science Foundation of China(No.81903832),the Key Research and Development Plan of Shaanxi Province(No.2022SF-182),the Fundamental Research Funds for the Central Universities(No.D5000210799);Shaanxi Provincial Traditional Chinese Medicine Administration"Double Chain Integration"Middle Youth Research and Innovation Team Project(No.2022-SLRH-LJ-007);Shanghai Science and Technology Innovation Action Plan(No.22S21902600).
Aralia taibaiensi,widely distributed in western China,particularly in the Qinba Mountains,has been utilized as a folk medicine for treating diabetes,gastropathy,rheumatism,and cardiovascular diseases.Saponins from A.t...
关键词:Aralia taibaiensis Apelin/apelin receptor Stroke P38 MAPK/ATF4 HIF-1A 
Association between uric acid-albumin ratio and spontaneous reperfusion in ST-segment elevation myocardial infarction patients
《Journal of Geriatric Cardiology》2025年第2期229-236,共8页Jing NAN Shuai MENG Ruo-Fei JIA Wei CHEN Xing-Sheng YANG Hong-Yu HU Ze-Ning JIN 
BACKGROUND The association between uric acid-albumin ratio(UAR)with different diseases has been evaluated before.However,the association between UAR with spontaneous reperfusion(SR)in patients with ST-segment elevatio...
关键词:PATIENTS admitted INFARCTION 
Post-reperfusion syndrome in liver transplant recipients:What is new in prevention and management?
《World Journal of Critical Care Medicine》2025年第2期65-74,共10页Austin James Puchany Ibtesam Hilmi 
Post-reperfusion syndrome(PRS)in liver transplant recipients remains one of the most dreaded complications in liver transplant surgery.PRS can impact the short-term and long-term patient and graft outcomes.The definit...
关键词:Liver transplant Post-reperfusion syndrome Machine perfusion Hypothermic machine perfusion Normothermic machine perfusion Caval blood flush vent Ischemic pre-conditioning 
ANP Increases Zn^(2+)Accumulation During Reperfusion in Ex Vivo and In Vivo Hearts
《Current Medical Science》2025年第1期35-50,共16页Yu-ting Ma Tong Laga Chong-ning Zhong Bing-qi Zhuang Hai-lian Quan Lan Hong 
supported by the National Natural Science Foundation of China(NSFC)(No.82360065 and No.81760047).
Objective Atrial natriuretic peptide(ANP)and Zn^(2+)have been shown to confer cardioprotection against ischemia/reperfu-sion(I/R)injury.Zn^(2+)alleviates myocardial hypertrophy and pulmonary hypertension by regulating...
关键词:Atrial natriuretic peptide ISCHEMIA/REPERFUSION Zn^(2+) Zn^(2+)transporter Zn2⁺transporter 8 Hypoxia-inducible factor 1-alpha PI3K 
Protective activity of adipose-derived stem cell extracellular vesicles in ischemia and/or reperfusion
《World Journal of Stem Cells》2025年第1期1-5,共5页Alexander E Berezin 
Increasing evidence of the significant clinical value of protection against ischemia/reperfusion injury has contributed to the realization of the independent importance of this approach in improving prognosis and redu...
关键词:Extracellular vesicles Adipose mesenchymal stem cells MicroRNA-21-5p Cardiac protection ISCHEMIA REPERFUSION 
CSF multi-omics of intracerebral hemorrhage from onset to reperfusion underscores lipid metabolism in functional outcome
《Science Bulletin》2025年第2期162-166,共5页Yibin Jiang Sin Man Lam Shuixian Zhang Huan Miao Yong Zhou Qian Zhang Tengyuan Zhou Hui Feng Ning Ding Haomiao Wang Ran Luo Yi Yin Hua Feng Guanghou Shui Rong Hu 
supported by the National Natural Science Foundation of China(81671228,32321004,92057202,92357308);the Ministry of Science and Technology of China(2021ZD0201702);Joint project of Chongqing Health Commission and Science and Technology Bureau(2023GGXM003);the National Key Research and Development Program of China(2018YFA0800901)。
Constituting 6.5%to 19.6%of all stroke cases worldwide,non-traumatic intracerebral hemorrhage(ICH)represents the most devastating form of stroke,with aging,male gender,and hypertension being important risk factors tha...
关键词:metabolism HEMORRHAGE INTRACEREBRAL 
Iron promotes both ferroptosis and necroptosis in the early stage of reperfusion in ischemic stroke被引量:1
《Genes & Diseases》2024年第6期495-509,共15页Bin Du Zijie Deng Kang Chen Zhangzhong Yang Junfen Wei Liuyao Zhou Jie Meng Ying Cheng Xin Tian Qing-Zhang Tuo Peng Lei 
upported by the National Key Research and Development Program of China (No.2021YFC2500100);1.3.5 Project for Disciplines of Excellence of West China Hospital of Sichuan University (No.ZYYC23016);the Key Research Projects of Sichuan Province,China (No.24SYSX0093);Major Science&Technology Program of Sichuan Province,China (No.2022ZDZX0021);the National Clinical Research Center for Geriatrics,West China Hospital,Sichuan University (China) (No.Z2023LC005);the Natural Science Foundation of Sichuan Province,China (No.2022NSFSC1509);the Fundamental Research Funds for the Central Universities (China) (No.2023SCU12074).
Programmed cell death contributes to neurological damage in ischemic stroke,especially during the reperfusion stage.Several cell death pathways have been tested preclinically and clinically,including ferroptosis,necro...
关键词:DEFEROXAMINE Ferroptosis IRON Ischemic stroke NECROPTOSIS 
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