supported by the National Natural Science Foundation of China(81671228,32321004,92057202,92357308);the Ministry of Science and Technology of China(2021ZD0201702);Joint project of Chongqing Health Commission and Science and Technology Bureau(2023GGXM003);the National Key Research and Development Program of China(2018YFA0800901)。
Constituting 6.5%to 19.6%of all stroke cases worldwide,non-traumatic intracerebral hemorrhage(ICH)represents the most devastating form of stroke,with aging,male gender,and hypertension being important risk factors tha...
Spontaneous intracerebral hemorrhage(ICH)accounts for 10-30%of all strokes worldwide and is more prevalent in Asians,Hispanics,and African Americans.^([1-3])Uncontrolled hypertension and anticoagulant use are the comm...
supported by the National Natural Science Foundation of China(numbers:81774416 and 81473764)。
Background: Blocking the Rho A/ROCK Ⅱ/MLC 2(Ras homolog gene family member A/Rho kinase Ⅱ/myosin light chain 2) signaling pathway can initiate neuroprotective mechanisms against neurological diseases such as stroke,...
Objective To evaluate the value of curative effect in neuromyelitis spectrum disease(NMOSD)based on circulatory function evaluation of intracerebral glymphatic system by using diffusion tensor imaging analysis along t...
Hyperhomocysteinemia(HHcy)is independently associated with poorer long-term prognosis in patients with intracerebral haemorrhage(ICH);however,the effect and mechanisms of HHcy on ICH are still unclear.Here,we evaluate...
State Key Laboratory of Trauma,Burn and Combined Injury(No.SKLYQ202002);National Natural Science Foundation of China(No.82030036);Chongqing Talent Program(No.4139Z2391);Southwest Hospital(No.SWH2018BJKJ-05)。
To the Editor:Spontaneous intracerebral hemorrhage(sICH)has a high incidence of acute cerebrovascular illness in elderly people in China,with high mortality and long-term functional impairment among survivors.However,...
supported in part by the National Science Foundation of China(81971094,81771274);the Advanced Innovation Center for Human Brain Protection,Capital Medical University,Beijing,China.
Background Stroke is a devastating disease,including intracerebral haemorrhage(ICH)and ischaemic stroke.Emerging evidences indicate that systemic inflammatory cascades after stroke contribute to brain damage.However,t...
Background and purpose NOTCH3 p.R544C mutation accounts for 5%of spontaneous intracerebral haemorrhage(ICH)in East Asian patients.We investigated whether certain CT features are associated with NOTCH3-related ICH.Meth...
This study was partially supported by grants from the Spanish Ministry of Science and Innovation(SAF2017-84267-R);Xunta de Galicia(Axencia Galega de Innovación(GAIN):IN607A2018/3);Instituto de Salud Carlos III(ISCIII)(PI17/00540,PI17/01103);Spanish Research Network on Cerebrovascular Diseases RETICS-INVICTUS PLUS(RD16/0019);by the European Union FEDER program.T.Sobrino(CPII17/00027),F.Campos(CPII19/00020)are recipients of research contracts from the Miguel Servet Program(Instituto de Salud Carlos III).
Objective To study the association between early growth of haematoma with biomarkers of endothelial dysfunction such as leukoaraiosis(LA)and the soluble tumour necrosis factor-like weak inducer of apoptosis(sTWEAK)in ...
BACKGROUND:The incidence of hypertensive intracerebral hemorrhage(HICH)has been increasing during the recent years in low-and middle-income countries.With high mortality and morbidity rates,it brings huge burden to th...