云南高校图书馆联盟文献共享服务平台- CAVEOLAE

CAVEOLAE: 作品数：82被引量：287H指数：9; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：廖端芳秦旭平刘彦梅暴军香谌赟更多>>; 相关机构：南华大学北京大学第三军医大学中山大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划湖南省自然科学基金国家高技术研究发展计划更多>>

“Baihui”(DU20)-penetrating “Qubin”(GB7) acupuncture on blood–brain barrier integrity in rat intracerebral hemorrhage models via the RhoA/ROCK Ⅱ/MLC 2 signaling pathway被引量：1: 《Animal Models and Experimental Medicine》2024年第5期740-757,共18页Ce Zhang Jia Zheng Xueping Yu Binglin Kuang Xiaohong Dai Lei Zheng Weiwei Yu Wei Teng Hongtao Cao Mingyue Li Jiayong Yao Xiaoying Liu Wei Zou; supported by the National Natural Science Foundation of China(numbers:81774416 and 81473764)。; Background: Blocking the Rho A/ROCK Ⅱ/MLC 2(Ras homolog gene family member A/Rho kinase Ⅱ/myosin light chain 2) signaling pathway can initiate neuroprotective mechanisms against neurological diseases such as stroke,...; 关键词：blood-brain barrier CAVEOLAE INTRACEREBRAL hemorrhage RhoA/ROCK II/MLC 2 signaling pathway SCALP ACUPUNCTURE

Miriplatin-loaded liposome,as a novel mitophagy inducer,suppresses pancreatic cancer proliferation through blocking POLG and TFAM-mediated mtDNA replication被引量：3: 《Acta Pharmaceutica Sinica B》2023年第11期4477-4501,共25页Xiaowei Wang Mengyan Wang Meilian Cai Rongguang Shao Guimin Xia Wuli Zhao; supported by grants from CAMS Innovation Fund for Medical Sciences (CIFMS) (2022-I2M-2-002,2021-I2M-1030,China);National Natural Science Foundation of China (No.81473249 and 81102464);Drug Innovation Major Project of China (2018ZX09711001-007-002);National Key Research and Development Program of China (2016YFA0201504);National Mega-project for Innovative Drugs (2014ZX09201042,China)。; Pancreatic cancer is a more aggressive and refractory malignancy.Resistance and toxicity limit drug efficacy.Herein,we report a lower toxic and higher effective miriplatin(MPt)-loaded liposome,LMPt,exhibiting totally ...; 关键词：Miriplatin-loaded liposome Pancreatic cancer Caveolae-mediated endocytosis Caveolin-1 MITOPHAGY Mitochondria DNA POLG TFAM

Caveolae在剪切力诱导过氧化氢引起小鼠肠系膜动脉舒张中的作用: 《中华老年心脑血管病杂志》2023年第7期746-750,共5页孙玮邢守欣贾青刘振东张华赵颖馨柴强; 国家自然科学基金(81470489,81973139,81670432)。; 目的探讨Caveolae在剪切力诱导的过氧化氢引起小鼠肠系膜动脉舒张中的作用。方法随机选取野生型或Cav-1基因敲除(Cav-1^(-/-))小鼠分离肠系膜动脉进行血管实验分组:野生型组,野生型+Catalase组,野生型去内皮(WT-endo)组,WT-endo+Catalas...; 关键词：细胞质膜微囊过氧化氢肠系膜动脉血管舒张内皮细胞剪切力 Cav-1基因敲除小鼠

Overexpression of Toll-like receptor 4 contributes to the internalization and elimination of Escherichia coli in sheep by enhancing caveolae-dependent endocytosis被引量：1: 《Journal of Animal Science and Biotechnology》2021年第4期1323-1338,共16页Yao Li Yue Zhao Xueling Xu Rui Zhang Jinlong Zhang Xiaosheng Zhang Yan Li Shoulong Deng Zhengxing Lian; supported by National Science and Technology Major Project of China(2016ZX08008-003).; Background:Gram-negative bacterial infections have a major economic impact on both the livestock industry and public health.Toll-like receptor 4(TLR4)plays a crucial role in host defence against Gram-negative bacteria...; 关键词：Caveolae-dependent endocytosis Host defence infection Inflammatory responses MONOCYTES Toll-like receptor 4

A DNA-based nanocarrier for efficient cancer therapy: 《Journal of Pharmaceutical Analysis》2021年第3期330-339,共10页Muhammad Abbas Mirza Muhammad Faran Ashraf Baig Yaliang Zhang Yu-Shun Yang Songyu Wu Yiqiao Hu Zhong-Chang Wang Hai-Liang Zhu; supported by the China Scholarship Council(CSC)grant(Grant No.20180500458)。; The study aimed to achieve enhanced targeted cytotoxicity and cell-internalization of cisplatin-loaded deoxyribonucleic acid-nanothread(CPT-DNA-NT),mediated by scavenger receptors into HeLa cells.DNA-NT was developed ...; 关键词：DNA-nanothread CISPLATIN Drug delivery Scavenger receptors CAVEOLAE HeLa cell line

The role of caveolae in endothelial dysfunction: 《Medical Review》2021年第1期78-91,共14页Jinlong He Zhen Cui Yi Zhu; supported by National Key Research and Development Program of China Grant(2019YFA0802003);National Natural Science Foundation of China Grants(81730014,81790621,82070451,and 81870313);Young Elite Scientists Sponsorship Program by CAST(2019QNRC001);Tianjin Municipal Science and Technology Project(18JCZDJC44900 and 17JCJQJC45700)。; Caveolae,the specialized cell-surface plasma membrane invaginations which are abundant in endothelial cells,play critical roles in regulating various cellular processes,including cholesterol homeostasis,nitric oxide p...; 关键词：ATHEROSCLEROSIS CAVEOLAE CAVEOLIN-1 endothelial cell INTEGRIN shear stress.

Compressive Stress Enhances Invasive Phenotype of Cancer Cells via Piezo1 Activation被引量：1: 《医用生物力学》2019年第A01期125-126,共2页Mingzhi Luo Kenneth KYHo Zhaowen Tong Linhong Deng Allen PLiu; supported by Key Program of NSF of China ( 11532003) to L.D.;NSF-MCB 1561794 to A.P.L.; In this study,we hypothesized that Piezo 1 channels mediate the compression-enhanced invasive phenotype of cancer cells via a caveolae-dependent mechanism.To test this hypothesis,we examined in vitro cultured human br...; 关键词：compressive stress CAVEOLAE Piezo1 INVADOPODIA MECHANOTRANSDUCTION

Fam198a, a member of secreted kinase, secrets through caveolae biogenesis pathway: 《Acta Biochimica et Biophysica Sinica》2018年第10期968-975,共8页Zhuang Wei Tao Liu Jigang Lei Yuan Wu Shilong Wang Kan Liao; This work was supported by the grants from the National Natura Science Foundation of China （Nos, 31370818 and 31701165）.; Fam198a is a member of four-jointed protein kinases, a secreted protein kinase family. It was identified as a caveolae-associated protein and colocalized with cavin-1 and caveolin-1 in both tissues and cells. The newl...; 关键词：Fam198a CAVEOLAE cavin-1 protein processing

Ultrastructural Findings, at Micrometric and Nanometric Scales, in Rectal and Muscular Mucosa of Patients with HIV/AIDS and Anorectal Pathology: 《International Journal of Clinical Medicine》2018年第5期481-493,共13页Annunziato Maria Antonieta Sardiñ as Carlos Finol Hector Carvajal Ana González Roschman De Gouveia Yetsenia García Estefanie Garibaldi Liseth; Objective: To determine the ultrastructural findings on Rectal Mucosa (RM) of patients with HIV/AIDS and anorectal pathologies (ARP), at micrometric and nanometric scales. Materials and methods: 5 patients were evalua...; 关键词：ANORECTAL PATHOLOGIES HIV/AIDS Transmission Electron Microscopy (TEM) Nanometric Scales RECTAL MUCOSA CAVEOLAE Endothelial Cell Nano-Drugs

细胞炎症反应与脂质代谢的相互作用及调节被引量：41: 《中国动脉硬化杂志》2017年第6期623-629,共7页龚勇珍孙少卫廖端芳; 国家自然科学基金项目(31371161);湖南省自然科学基金项目(2015JJ6077);湖南省药学重点学科建设项目; 本文讨论了脂质代谢紊乱与炎症反应在动脉粥样硬化发生发展中的作用及相互关系。脂质代谢失衡诱发炎症反应;脂蛋白异常修饰和异常定位调节炎症反应,脂质代谢紊乱通过影响单核细胞、M1/M2漂移、核苷酸结合寡聚化结构域样受体含pyrin结构...; 关键词：细胞炎症脂质代谢 Caveolae/Caveolin 核因子κB通路过氧化体增殖物激活型受体通路

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