SYNAPTOGENESIS

作品数:28被引量:49H指数:3
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相关领域:医药卫生生物学更多>>
相关作者:罗春霞朱东亚胡荣蔡文琴更多>>
相关机构:南京医科大学第三军医大学更多>>
相关期刊:《Signal Transduction and Targeted Therapy》《Journal of Behavioral and Brain Science》《World Journal of Experimental Medicine》《Neural Regeneration Research》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Modularization of adhesion G protein-coupled receptor(aGPCR)structure:how alternative splicing regulates synaptogenesis
《Signal Transduction and Targeted Therapy》2024年第5期1793-1795,共3页Tobias Langenhan 
The author’s research is supported by the German Research Foundation(DFG)in CRC1423/project number 421152132;by the German Ministry of Education and Research(BMBF)/project number 03VP11220.
A recent report has uncovered a fascinating aspect of how neurons utilize alternative splicing of transcripts of an adhesion G protein-coupled receptor(aGPCR)gene to serve specific functions in the life of a synapse.1...
关键词:GPCR utilize operations 
The Contributions of Thrombospondin-1 to Epilepsy Formation被引量:1
《Neuroscience Bulletin》2024年第5期658-672,共15页Yao Cheng Yujie Zhai Yi Yuan Qiaoyun Wang Shucui Li Hongliu Sun 
supported by the Natural Science Foundation of Shandong Province(ZR2021MH034 and ZR2022MH059);the National Natural Science Foundation of China(81573412).We’d like to thank Editage for English language editing.
Epilepsy is a neural network disorder caused by uncontrolled neuronal hyperexcitability induced by an imbalance between excitatory and inhibitory networks.Abnormal synaptogenesis plays a vital role in the formation of...
关键词:Thrombospondin-1 EPILEPTOGENESIS SYNAPTOGENESIS HYPEREXCITABILITY 
Differentiation and functional connectivity of fetal tectal transplants
《Neural Regeneration Research》2023年第11期2325-2331,共7页Alan R.Harvey 
Data from studies analyzing the differentiation and functional connectivity of embryo nic neural tissue grafted into the mammalian nervous system has led to the clinical testing of the fetal graft approach in patients...
关键词:axon regeneration DIFFERENTIATION embyronic grafts fetal tissue neural precursors RETINOTECTAL stem cells superior colliculus SYNAPTOGENESIS transplantation 
Activity-Dependent Phosphorylation of CDKL5 at Serine 407 Regulates Synaptogenesis and Plasticity
《Neuroscience Bulletin》2023年第9期1454-1458,共5页Mengying Jiang Qiwu Xu Can Yang Dan Li Ji-Wei Liu Yuxian Zhang Yong-Chuan Zhu Zhi-Qi Xiong 
This work was supported by the Ministry of Science and Technology(2018YFA0801404);the Shanghai Municipal Science and Technology Major Project(2018SHZDZX05).
Dear Editor,The X-linked gene cyclin-dependent kinase-like 5(CDKL5)encodes a serine/threonine kinase that is associated with CDKL5-deficiency disorder(CDD),a severe developmental and epileptic encephalopathy character...
关键词:seizures enriched CDK 
C-X-C chemokine receptor type 7 antibody enhances neural plasticity after ischemic stroke被引量:1
《Neural Regeneration Research》2023年第9期1976-1982,共7页Xiao-Qian Zhang Xiao-Yin Wang Bing-Chao Dong Mei-Xuan Li Yu Wang Ting Xiao Shan-Shan Zhao 
supported by the National Natural Science Foundation of China,Nos.81401002 (to SSZ),81801 053 (to XQZ)。
Stromal cell-derived factor-1 and its receptor C-X-C chemokine receptor 4(CXCR4) have been shown to regulate neural regeneration after stroke.Howeve r,whether stromal cell-derived factor-1 receptor CXCR7,which is wide...
关键词:axonal regeneration cerebral ischemia C-X-C chemokine receptor 4 CXCR7 antibody neural plasticity RAS/ERK pathway REMYELINATION stroke stromal cell-derived factor-1 SYNAPTOGENESIS 
Neuronal guidance genes in health and diseases被引量:1
《Protein & Cell》2023年第4期238-261,共24页Junichi Yuasa-Kawada Mariko Kinoshita-Kawada Yoshio Tsuboi Jane Y.Wu 
Neurons migrate from their birthplaces to the destinations,and extending axons navigate to their synaptic targets by sensing various extracellular cues in spatiotemporally controlled manners.These evolutionally conser...
关键词:axon guidance neuronal migration SYNAPTOGENESIS neural circuit formation neural mapping cell-cell communications ANGIOGENESIS ORGANOGENESIS cancermetastasis 
Interactions Between Astrocytes and Oligodendroglia in Myelin Development and Related Brain Diseases被引量:1
《Neuroscience Bulletin》2023年第3期541-552,共12页Xuelian Hu Guangdan Yu Xiang Liao Lan Xiao 
supported by the Ministry of Science and Technology of China(2021ZD0201700);the National Natural Science Foundation of China(31921003).
Astrocytes(ASTs)and oligodendroglial lineage cells(OLGs)are major macroglial cells in the central nervous system.ASTs communicate with each other through connexin(Cx)and Cx-based network structures,both of which allow...
关键词:ASTROCYTE OLIGODENDROGLIA Glial network MYELINATION SYNAPTOGENESIS Neuroinfammation 
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury被引量:2
《Acta Biochimica et Biophysica Sinica》2022年第9期1289-1300,共12页Sujuan Liu Haili Tian Yanmei Niu Chunxia Yu Lingjian Xie Zhe Jin Wenyan Niu Jun Ren Li Fu Zhi Yao 
the grants from the China Postdoctoral Science Foundation(No.2019M661042);the National Natural Science Foundation of China(Nos.81501071,31871206 and 31671237).
Neuronal regeneration and functional recovery are severely compromised following traumatic brain injury(TBl).Treatment options,including cell transplantation and drug therapy,have been shown to benefit TBl,although th...
关键词:traumatic brain injury TRANSPLANTATION neural stem cells valproic acid N-METHYL-D-ASPARTATE 
Neurobiology of Neuronal Network Alteration in Intellectual Disability Related to Fetal Alcohol Spectrum Disorders
《Journal of Behavioral and Brain Science》2022年第3期43-81,共39页Abdoulaye Bâ 
The molecular and cellular mechanisms by which alcohol produces its deleterious effects on neuronal networks are only now beginning to be understood. This review focused on alcohol-induced neurobiological alterations ...
关键词:Fetal Alcohol Spectrum Disorders Intellectual Disability Neuronal Network Axogenesis SYNAPTOGENESIS Myelinogenesis 
Cathepsins in neuronal plasticity
《Neural Regeneration Research》2021年第1期26-35,共10页Amanda Phuong Tran Jerry Silver 
JS was funded by NINDS(NS25713);Brumagin-Nelson Fund;Kaneko Family Fund;the Hong Kong Spinal Cord Injury Fund.
Proteases comprise a variety of enzymes defined by their ability to catalytically hydrolyze the peptide bonds of other proteins,resulting in protein lysis.Cathepsins,specifically,encompass a class of at least twenty p...
关键词:axon regeneration CATHEPSIN CSPGs extracellular matrix growth cone LYSOSOMES neuronal plasticity PROTEASE remodeling spinal cord injury SYNAPTOGENESIS 
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