Modularization of adhesion G protein-coupled receptor(aGPCR)structure:how alternative splicing regulates synaptogenesis  

作　　者：Tobias Langenhan 

机构地区：[1]Rudolf Schönheimer Institute of Biochemistry,Division of General Biochemistry,Medical Faculty,Leipzig University,Leipzig,Germany [2]Comprehensive Cancer Center Central Germany(CCCG),Leipzig University,Leipzig,Germany [3]Institute of Biology,Faculty of Life Sciences,Leipzig University,Leipzig,Germany

出　　处：《Signal Transduction and Targeted Therapy》2024年第5期1793-1795,共3页信号转导与靶向治疗（英文）

基　　金：The author’s research is supported by the German Research Foundation(DFG)in CRC1423/project number 421152132;by the German Ministry of Education and Research(BMBF)/project number 03VP11220.

摘　　要：A recent report has uncovered a fascinating aspect of how neurons utilize alternative splicing of transcripts of an adhesion G protein-coupled receptor(aGPCR)gene to serve specific functions in the life of a synapse.1 The work provides significant insight into the ability of cells to support distinct biochemical and physiological operations through post-transcriptional processing of genetic information that is encoded in a single aGPCR locus.

关 键 词：GPCR utilize operations 

分 类 号：R730[医药卫生—肿瘤]