EPILEPTOGENESIS

作品数：29被引量：55H指数：5
导出分析报告
相关领域：医药卫生更多>>
相关期刊：《Chinese Medical Journal》《Neuroimmunology and Neuroinflammation》《Acta Epileptologica》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
相关基金：国家自然科学基金上海市浦江人才计划项目中国博士后科学基金国家教育部博士点基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
The sigma-1 receptor-TAMM41 axis modulates neuroinflammation and attenuates memory impairment during the latent period of epileptogenesis
《Animal Models and Experimental Medicine》2025年第2期197-208,共12页Jianlun Ji Ce Gao Qinghua Wang Xiaoxia Jia Hao Tian Yaqin Wei Zhidong Liu Yun Wang Lin Guo 
This project was supported by grants from the National Natural Science Foundation of China(Grant Nos.81872847 and 82173803);the Science and Technology Planning Project of Xuzhou(Grant No.KC22256);the Science and Technology Developing Fund of The Affiliated Hospital of Xuzhou Medical University(Grant No.2021ZA14)。
Background:Therapy in the latent period is favorable for retarding the process of epileptogenesis.Recently,we have discovered that the activated sigma-1 receptor(Sig-1R)attenuates the hippocampus pathological injury a...
关键词：EPILEPTOGENESIS memory impairment mitochondrial translocator assembly and maintenance 41 homolog NEUROINFLAMMATION sigma-1 receptor 
Krüppel-like factors:potential roles in blood-brain barrier dysfunction and epileptogenesis
《Acta Pharmacologica Sinica》2024年第9期1765-1776,共12页Ana Beatriz Santos Andreia Carona Miren Ettcheto Antoni Camins Amílcar Falcão Ana Fortuna Joana Bicker 
The authors acknowledge Fundo Europeu de Desenvolvimento Regional(FEDER)through Portugal2020 in the scope of the Operational Programme for Competitiveness and Internationalization;Fundação para a Ciência e Tecnologia(FCT),Portuguese Agency for Scientific Research,within the scope of the research project 2022.03133.PTDC and Ph.D.research grant 2021.06125.BD;Spanish Ministerio de Ciencia e Innovación(PID2021-123462OB-I00);the Generalitat de Catalunya(2021 SGR 00288);CIBERNED(Grant CB06/05/2004);Institut de Neurociències UB,(CEX2021-001159-M).ME is Serra Hunter fellow.
Epilepsy is a chronic and debilitating neurological disorder,known for the occurrence of spontaneous and recurrent seizures.Despite the availability of antiseizure drugs,30%of people with epilepsy experience uncontrol...
关键词：blood-brain barrier cerebrovascular dysfunction EPIGENETICS epilepsy krüppel-like factors NEUROINFLAMMATION 
Low-frequency Stimulation at the Subiculum Prevents Extensive Secondary Epileptogenesis in Temporal Lobe Epilepsy被引量：1
《Neuroscience Bulletin》2024年第5期564-576,共13页Yujia Shen Yiwei Gong Xiaoli Da Shajing Gao Shuo Zhang Minjuan Sun Yuanzhi Yang Xiaoyun Qiu Menghan Li Yang Zheng Fan Fei Yi Wang Zhong Chen Cenglin Xu 
supported by grants from the National Natural Science Foundation of China(U21A20418 and 82173796);the Natural Science Foundation of Zhejiang Province(LD22H310003);the Research Project of Zhejiang Chinese Medical University(2023JKZDZC04).
Secondary epileptogenesis is characterized by increased epileptic susceptibility and a tendency to generate epileptiform activities outside the primary focus.It is one of the major resultants of pharmacoresistance and...
关键词：Secondary epileptogenesis Low-frequency stimulation SUBICULUM Temporal lobe epilepsy 
The Neurovascular Unit Dysfunction in the Molecular Mechanisms of Epileptogenesis and Targeted Therapy被引量：1
《Neuroscience Bulletin》2024年第5期621-634,共14页Xiuxiu Liu Ying Zhang Yanming Zhao Qian Zhang Feng Han 
supported by the National Key Research and Development Program of China(81930103);the National Natural Science Foundations of China(82104162);the Natural Science Foundation of Jiangsu Province(BK20210539).
Epilepsy is a multifaceted neurological syndrome characterized by recurrent,spontaneous,and synchronous seizures.The pathogenesis of epilepsy,known as epileptogenesis,involves intricate changes in neurons,neuroglia,an...
关键词：EPILEPTOGENESIS Neurovascular unit Molecular mechanisms Drug targets 
The Contributions of Thrombospondin-1 to Epilepsy Formation被引量：1
《Neuroscience Bulletin》2024年第5期658-672,共15页Yao Cheng Yujie Zhai Yi Yuan Qiaoyun Wang Shucui Li Hongliu Sun 
supported by the Natural Science Foundation of Shandong Province(ZR2021MH034 and ZR2022MH059);the National Natural Science Foundation of China(81573412).We’d like to thank Editage for English language editing.
Epilepsy is a neural network disorder caused by uncontrolled neuronal hyperexcitability induced by an imbalance between excitatory and inhibitory networks.Abnormal synaptogenesis plays a vital role in the formation of...
关键词：Thrombospondin-1 EPILEPTOGENESIS SYNAPTOGENESIS HYPEREXCITABILITY 
Metabotropic glutamate receptors(mGluRs)in epileptogenesis:an update on abnormal mGluRs signaling and its therapeutic implications被引量：2
《Neural Regeneration Research》2024年第2期360-368,共9页Leyi Huang Wenjie Xiao Yan Wang Juan Li Jiaoe Gong Ewen Tu Lili Long Bo Xiao Xiaoxin Yan Lily Wan 
supported by the Natural Science Foundation of Hunan Province,No.2021JJ30389(to JG);the Key Research and Development Program of Hunan Province of China,Nos.2022SK2042(to LL)and 2020SK2122(to ET)。
Epilepsy is a neurological disorder characterized by high morbidity,high recurrence,and drug resistance.Enhanced signaling through the excitatory neurotransmitter glutamate is intricately associated with epilepsy.Meta...
关键词：antiepileptic drugs EPILEPTOGENESIS metabotropic glutamate receptors(mGluRs) signal pathways therapeutic potentials 
High amplitude high frequency oscillations during posttraumatic epileptogenesis
《Brain Science Advances》2023年第4期275-282,共8页Jagannathan Rangarajan Udaya Kumar 
supported by research grants from the National Institutes of Health,USA。
Background: The aim of the present study was to investigate if high amplitude high frequency oscillations(haHFOs) could be a biomarker of posttraumatic epileptogenesis. Methods: After an initial craniotomy of rats and...
关键词：traumatic brain injury EPILEPSY high frequency oscillations BIOMARKER 
Biomolecular mechanisms of epileptic seizures and epilepsy: a review
《Acta Epileptologica》2023年第4期201-222,共22页Komang Trisna Sumadewi Saktivi Harkitasari David Christopher Tjandra 
Epilepsy is a recurring neurological disease caused by the abnormal electrical activity in the brain. This disease has caused about 50 new cases in 100,000 populations every year with the clinical manifestations of aw...
关键词：Epilectic seizures EPILEPSY EPILEPTOGENESIS Molecular mechanism 
Is Autonomic Nervous System Involved in the Epileptogenesis in Preterm Neonates?
《Maternal-Fetal Medicine》2023年第3期173-181,共9页Raffaele Falsaperla Giovanna Vialiti Janette Mailo Giovanni Corsello Martino Ruggieri 
Autonomic nervous system dysfunction has been described with focal and generalized epileptic seizures;occurring during their ictal,interictal,or postictal states.International League Against Epilepsy Seizure Classific...
关键词：PREMATURE APNEA Autonomic seizures Brain Neonatal epilepsy NEONATES 
Pro-and anti-epileptic roles of microglia被引量：10
《Neural Regeneration Research》2021年第7期1369-1371,共3页Shinichi Kinoshita Ryuta Koyama 
supported in part by a Grant-in-Aid for Scientific Research (B)(17H03988 to RK) from JSPS and JST PRESTO (JPMJPR18H4 to RK)。
Microglia are brain-resident immune cells that contribute to the maintenance of brain homeostasis.In the epileptic brain, microglia show various activation phenotypes depending on the stage of epileptogenesis.Therefor...
关键词：EPILEPSY EPILEPTOGENESIS inflammatory cytokines MICROGLIA NEUROGENESIS neuron-microglia interaction SEIZURE 
全选清除导出
共3页<123>
检索报告 对象比较 聚类工具 使用帮助 返回顶部