云南高校图书馆联盟文献共享服务平台- NIFEDIPINE

NIFEDIPINE: 作品数：71被引量：474H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：赵连友施仲伟王滨燕杨新春李南方更多>>; 相关机构：武汉大学重庆医科大学北京大学第一医院第四军医大学唐都医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划上海市卫生局科技发展基金北京市自然科学基金更多>>

Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice被引量：2: 《Acta Pharmacologica Sinica》2023年第1期44-57,共14页Cheng Peng Lijun Yang Chuan Zhang Yu Jiang Liu-wen-xin Shang Jia-bei He Zhen-wei Zhou Xia Tao Lu Tie Alex F.Chen He-hui Xie; This work was supported by grants from the Ministry of Science and Technology of China (2021YFA0804803);the National Natural Science Foundation of China (81870189,82070266,81900243,81930012,81730013,92168120 and 81974506);the Beijing Natural Science Foundation(Z200019).; It is of great clinical significance to develop potential novel strategies to prevent diabetic cardiovascular complications.Endothelial progenitor cell(EPC)dysfunction is a key contributor to diabetic vascular complic...; 关键词：diabetes NIFEDIPINE endothelial progenitor cells ANGIOGENESIS cerebral ischemia THROMBOSPONDINS

Clinical presentation and management of drug-induced gingival overgrowth: A case series被引量：1: 《World Journal of Clinical Cases》2021年第32期9926-9934,共9页Li Fang Bao-Chun Tan; by the Nanjing Clinical Research Center for Oral Diseases,No.2019060009;the Nanjing Medical Science and Technology Development Program,No.YKK17139;the Medical Innovation Team of Scientific and Educational Health in the Jiangsu Province,No.CXTDB2017014.; BACKGROUND We report three patients with drug-induced gingiva overgrowth(DIGO)caused by nifedipine,a calcium channel blocker,who were treated and followed up for 1–3 years.We discussed their symptoms,treatment proces...; 关键词：Drug-induced gingiva overgrowth NIFEDIPINE Periodontal surgery Treatment prognosis Case report

Panax Notoginseng Saponins Increases the Blood Concentration of Nifedipine by Inhibiting CYP3A4 Enzyme through PXR-and CAR-Mediated Pathway: 《World Journal of Traditional Chinese Medicine》2021年第3期332-338,共7页Qiu-Hong Li Jiao Zhao Ai-Xia Ju Yong Hu Qing-Song Qie Hong-Bin Xiao Guang Xu Xi-Jun Wang; supported by Heilongjiang Natural Science Foundation(No.LH2019H107);Innovation Fund for postgraduates of Heilongjiang University of Chinese Medicine(No.2020yjscx058)。; Objective:To explore the mechanism underlying the effect of Panax notoginseng saponins(PNS)on the pharmacokinetics of nifedipine(NF)in rats.Materials and Methods:Twenty-four rats were randomly divided into blank(BL)gr...; 关键词：CAR CYP3A4 NIFEDIPINE Panax notoginseng saponins PHARMACOKINETICS PXR

Drug-induced gingival overgrowth in cardiovascular patients被引量：1: 《World Journal of Cardiology》2021年第4期68-75,共8页Lucija Bajkovec Anna Mrzljak Robert Likic Ivan Alajbeg; Drug-induced gingival overgrowth(DIGO)is a pathological growth of gingival tissue,primarily associated with calcium channel blockers and immunosuppressants.Consequently,it is mainly seen in cardiovascular and transpla...; 关键词：Drug-induced gingival overgrowth Calcium channel blocker NIFEDIPINE

硝苯地平(nifedipine): 《中国合理用药探索》2021年第3期84-84,共1页; 【药理作用】①为二氢吡啶类钙通道阻断药,可选择性抑制钙离子经细胞膜流入血管平滑肌和心肌细胞,降低细胞内钙离子水平,从而改变心肌电生理、抑制心肌收缩性和舒张血管,降低血压。②能同时舒张正常供血区和缺血区的冠状动脉,拮抗自发...; 关键词：冠状动脉痉挛心肌电生理心脏后负荷心肌收缩性外周阻力麦角新碱心肌代谢舒张血管

miR-4651 inhibits cell proliferation of gingival mesenchymal stem cells by inhibiting HMGA2 under nifedipine treatment被引量：3: 《International Journal of Oral Science》2020年第2期132-141,共10页Xiao Han Ruzhuang Yang Haoqing Yang Yangyang Cao Nannan Han Chen Zhang Ruitang Shi Zhengting Zhang Zhipeng Fan; supported by grants from the National Natural Science Foundation of China(81625005 to Z.P.F.);the Program for“Hundred-Thousand-Ten thousand”Talents in Beijing(2018A16 to Z.P.F.)。; Drug-induced gingival overgrowth(DIGO) is recognized as a side effect of nifedipine(NIF);however, the underlying molecular mechanisms remain unknown. In this study, we found that overexpressed mi R-4651 inhibits cell ...; 关键词：HMGA2 GINGIVAL INHIBITING

Role of kaempferol to increase bioavailability and pharmacokinetics of nifedipine in rats被引量：5: 《Chinese Journal of Natural Medicines》2019年第9期690-697,共8页PARK Ji-Won CHOI Jin-Seok; Herein,the purpose of this study is to evaluate the effects of kaempferol on bioavailability and pharmacokinetics of nifedipine and its metabolite dehydronifedipine in rats.The experimental design is based on with or ...; 关键词：NIFEDIPINE KAEMPFEROL CYP3A4 P-GP PHARMACOKINETICS BIOAVAILABILITY

The Effect of Oral Nifedipine versus Parenteral Magnesium Sulfate and Ritodrine for Tocolysis in Patients with Threatened Preterm Labor: A Randomized Controlled Trial: 《Open Journal of Obstetrics and Gynecology》2019年第8期1142-1150,共9页Safwat A. Salman Dina Habib Mohamed Atef Ahmed M. Abbas; Background: Preterm labor is a serious cause of neonatal morbidity and mortality. This study aims to compare the effects of nifedipine, Magnesium sulfate and ritodrine as tocolytic drugs in patients presented with thr...; 关键词：TOCOLYSIS PRETERM Labour NIFEDIPINE RITODRINE

Therapeutic Effect of Nifedipine Combined with Enalapril on Elderly Patients with Coronary Heart Disease Complicated with Hypertension: 《Journal of Clinical and Nursing Research》2018年第6期1-4,共4页Xiaoye Wang; The objective of this study was to analyze the efficacy of combined drug therapy for elderly patients with coronary heart disease and hypertension.66 elderly patients with coronary heart disease and hypertension were ...; 关键词：old age CORONARY heart disease HYPERTENSION NIFEDIPINE ENALAPRIL

Preparation and Antidiabetic Effect of Orally Administered Nifedipine‐Loaded Solid Lipid Nanoparticles in Fructose-Induced Diabetic Rats: 《Pharmacology & Pharmacy》2018年第10期457-471,共15页Sabarni Sarker Md. Ashraf Ali Ranjan Kumar Barman Shuji Noguchi Yasunori Iwao Shigeru Itai Mir Imam Ibne Wahed; The use of Nifedipine (NI), a dihydropyridine calcium channel blocker, is limited due to its poor aqueous solubility. However, NI loaded solid-lipid nanoparticles (NI-SLN) are known to exhibit suitable pharmacokinetic...; 关键词：Formulation Solid LIPID Nanoparticle CALCIUM Channel BLOCKER NIFEDIPINE FRUCTOSE Diabetes

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