AMPHIREGULIN

作品数：9被引量：14H指数：2
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相关领域：医药卫生更多>>
相关作者：周日易晟更多>>
相关机构：南京大学南通大学更多>>
相关期刊：《Neuroimmunology and Neuroinflammation》《Journal of Forensic Science and Medicine》《Frontiers of Medicine》《中国口腔颌面外科杂志》更多>>
相关基金：国家自然科学基金广东省自然科学基金更多>>
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The protective roles of integrin α4β7 and Amphiregulin-expressing innate lymphoid cells in lupus nephritis
《Cellular & Molecular Immunology》2024年第7期723-737,共15页Seungwon Ryu Kyung Ah Kim Jinwoo Kim Dong Hun Lee Yong-Soo Bae Hajeong Lee Byoung Choul Kim Hye Young Kim 
supported by grants from the National Research Foundation of Korea(SRC2017R1A5A1014560,RS-2023-00217798,RS-2023-00211566 and NRF-2022R1A2C3007730)。
Type 2 innate lymphoid cells (ILC2s) have emerged as key regulators of the immune response in renal inflammatory diseases such as lupus nephritis. However, the mechanisms underlying ILC2 adhesion and migration in the ...
关键词：Innate lymphoid cells Tissue residency Adhesion molecules INTEGRINS Kidney Lupus nephritis AMPHIREGULIN 
A distinct“repair”role of regulatory T cells in fracture healing
《Frontiers of Medicine》2024年第3期516-537,共22页Tingting Wu Lulu Wang Chen Jian Zhenhe Zhang Ruiyin Zeng Bobin Mi Guohui Liu Yu Zhang Chen Shi 
supported by the National Natural Science Foundation of China(Nos.82274026 and 81901884).
Regulatory T cells(Tregs)suppress immune responses and inflammation.Here,we described the distinct nonimmunological role of Tregs in fracture healing.The recruitment from the circulation pool,peripheral induction,and ...
关键词：regulatory T cells fracture healing AMPHIREGULIN NON-UNION OSTEOGENESIS 
血清sFlt-1、Amphiregulin水平联合在预测子痫前期孕妇妊娠结局中的应用价值被引量：1
《中国优生与遗传杂志》2023年第12期2520-2524,共5页张萍萍 苗晶 王志华 
张家口市重点研发计划项目大健康和生物医疗专项(2021106D)。
目的探讨可溶性血管内皮生长因子受体-1(sFlt-1)、双调蛋白(Amphiregulin)在子痫前期孕妇血清中的表达,以及在妊娠结局中的应用价值。方法收集2020年2月至2021年6月张家口市第一医院收治的子痫前期62例患者作为研究对象;另选取同期正常...
关键词：子痫前期 可溶性血管内皮生长因子受体-1 双调蛋白 妊娠结局 
Forensic Significance of Messenger RNA and Protein Expression of Genes Downstream of Hypoxia Inducible Factor 2 in Myocardial Tissue for Death Discrimination
《Journal of Forensic Science and Medicine》2023年第3期271-280,共10页Xingyu Ma Yeming Li Ya Xi Liyang Su Yuxing Tong Chun Wang Dong Zhao 
the National Natural Science Foundation of China(Grant No.81971796).
Background: As a heterodimeric transcription factor, hypoxia-inducible factor 2 alpha subunit (HIF2A), is an important member of the HIF family. It plays a significant role in the hypoxia adaptation process by regulat...
关键词：Cause of death hypoxia-inducible factor-2 alpha subunit myocardial infarction peroxisome proliferator-activated receptor-α potassium large conductance calcium-activated channel subfamily M-β1 recombinant amphiregulin 
子痫前期患者外周血及胎盘组织中Amphiregulin表达水平及与妊娠结局关系被引量：4
《中国计划生育学杂志》2022年第8期1776-1780,共5页刘红梅 刘晓玲 潘明霞 钟丽 
目的:探讨子痫前期患者外周血和胎盘组织中双调蛋白(amphiregulin)表达水平及与妊娠结局的关系。方法:选取2019年6月-2020年9月本院收治的子痫前期孕妇203例临床资料,分为子痫前期轻度组(102例)和子痫前期重度组(101例),产前检查健康孕...
关键词：子痫前期 外周血 胎盘组织 双调蛋白 妊娠结局 
Isorhapontigenin protects against doxorubicin-induced cardiotoxicity via increasing YAP1 expression被引量：10
《Acta Pharmaceutica Sinica B》2021年第3期680-693,共14页Panxia Wang Minghui Wang Yuehuai Hu Jianxing Chen Yanjun Cao Cui Liu Zhongkai Wu Juan Shen Jing Lu Peiqing Liu 
supported by grants from the National Natural Science Foundation of China (81872860, 81803521, 81673433);National Major Special Projects for the Creation and Manufacture of New Drugs (2019ZX09301104, China);Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (2017BT01Y093, China);National Engineering and Technology Research Center for New drug Druggability Evaluation(Seed Program of Guangdong Province, 2017B090903004,China);Natural Science Foundation of Guangdong Province(2019A1515010273, China);Foundation from Guangdong Traditional Medicine Bureau (20191060, China);Fundamental Research Funds for the Central Universities (19ykpy131, China);Research and Industrialization team of Taxus chinensis var.mairel (2014YT02S044, China)。
As an effective anticancer drug, the clinical limitation of doxorubicin(Dox) is the time-and dose-dependent cardiotoxicity. Yes-associated protein 1(YAP1) interacts with transcription factor TEA domain 1(TEAD1) and pl...
关键词：ISORHAPONTIGENIN YAP1 DOXORUBICIN CARDIOTOXICITY Cardiomyocytes apoptosis TEAD1 Connective tissue growth factor AMPHIREGULIN 
Resolution of inflammation and repair after ischemic brain injury
《Neuroimmunology and Neuroinflammation》2020年第3期264-276,共13页Akihiko Yoshimura Minako Ito 
This work was supported by JSPS KAKENHI(S)JP17H06175,Challenging Research(P)JP18H05376,and AMED-CREST JP20gm1110009 to Yoshimura A;JSPS KAKENHI 17K15667,19H04817,and 19K16618,AMED-PRIME 20gm6210012 to Ito M and by the Tomizawa Jun-ichi&Keiko Fund of Molecular Biology Society of Japan for Young Scientists,a Research Grant for Young Investigators by The Mitsubishi Foundation;the Mochida Memorial Foundation for Medical and Pharmaceutical Research;the Takeda Science Foundation;the Uehara Memorial Foundation;the Naito Memorial Foundation;the Kanae Foundation;the SENSHIN Medical Research Foundation;the Astellas Foundation for Research on Metabolic Disorders,an Inoue Research Award,a Life Science Research Award,and Keio Gijuku Academic Developmental Funds.
After ischemic stroke, proinflammatory molecules known as danger-associated molecular patterns (DAMPs) originating from damaged brain cells recruit and activate immune cells (neutrophils, macrophages, lymphocytes) fur...
关键词：DAMPS tissue repair macrophages regulatory T cells AMPHIREGULIN IL-33 
Membrane-anchored growth factor amphiregulin is targeted to inner nuclear membrane via retrograde membrane trafficking
《中国口腔颌面外科杂志》2008年第B05期143-144,共2页Mayumi Isokane, Miki Hieda Hiroyuki Hamakawa Shigeki Higashiyama 
关键词：角化细胞内分泌因子 细胞表面 隔膜 临床分析 
Amphiregulin Antisense RNA Delivered by Adnovirus Suppresses Growth of Breast Cancer Cells In Vitro and In Vivo
《Chinese Journal of Clinical Oncology》2005年第2期533-537,共5页LinMa VoahangyRandrianarison FabienCalvo 
OBJECTIVE To investigate the therapeutic potential of amphiregulin antisense RNA delivered by adenoviral vector in a human breast cancer model.METGODS Human amphiregulin cDNA was subcloned in the opposite orientation ...
关键词：RNA传递 病理机制 胸腺癌 肿瘤细胞 
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