云南高校图书馆联盟文献共享服务平台- DAMPS

DAMPS: 作品数：28被引量：172H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：吴丰华柯文杰邬善敏张小霞袁方均更多>>; 相关机构：中南大学安徽医科大学西北农林科技大学华中科技大学更多>>; 相关期刊：《Neuroimmunology and Neuroinflammation》《腹部外科》《武汉大学学报（医学版）》《华中科技大学学报（医学版）》更多>>; 相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划湖北省自然科学基金更多>>

山麦冬皂苷B调节DAMPs释放诱导免疫源性细胞死亡的抗肿瘤机制研究: 《辽宁中医杂志》2024年第11期150-153,I0002-I0004,共7页臧海洋杨君伶陈秋峰曹培杨晓慧; 国家自然科学基金青年科学基金项目(82004279);南通市第六期江海英才培养项目(通委人才办[2022]12号);南通市青年医学重点人才项目(通卫科教[2021]15号)。; 目的探讨Spicatoside B对肺癌细胞的增殖、凋亡和DAMPs释放的影响,并明确凋亡与DAMPs释放之间的关系。方法将不同浓度的SP-B作用于A549和H1299细胞株24 h,CCK8检测细胞增殖活性;根据CCK8结果,选取药物浓度,干预细胞24 h,流式细胞仪检测...; 关键词：肺癌 Spicatoside B 凋亡 DAMPS ICD

诱导抑郁症患者小胶质细胞炎性反应的机制被引量：1: 《基础医学与临床》2024年第7期1029-1033,共5页张昊孙浩廖红; 国家自然科学基金(82073831);重庆市自然科学基金(CSTB2023NSCQ-MSX0656);中国博士后科学基金(2023M733889)。; 小胶质细胞炎性反应是抑郁症患者及相关动物模型中广泛观察到的病理现象,与抑郁症密切相关。抑郁症中诱导小胶质细胞炎性反应的机制包括下丘脑-垂体-肾上腺(HPA)轴激活后糖皮质激素水平变化直接或间接的调控作用、肠道微生物代谢物通过...; 关键词：抑郁症小胶质细胞炎性反应下丘脑-垂体-肾上腺(HPA)轴脑肠轴损伤相关分子模式(DAMPs)

Plant cell wall-mediated disease resistance:Current understanding and future perspectives被引量：1: 《Molecular Plant》2024年第5期699-724,共26页Antonio Molina Lucıa Jorda Miguel Angel Torres Marina Martın-Dacal Diego Jose Berlanga Patricia Fernandez-Calvo Elena Gomez-Rubio Sonsoles Martın-Santamarıa; supported by grant PID2021-126006OB-I00 to A.M.and L.J.;grant PID20220-113588RB-I00 to S.M.-S;funded by MCIN/AEI/10.13039/501100011033;by ERDF A way of making Europe.D.J.B.;supported by PRE2019-091276 and P.F.-C.by postdoctoral fellowships financially supported by the Severo Ochoa Program for Centres of Excellence in R&D(grants SEV-2016-0672 and CEX2020-000999-S);funded by MCIN/AEI/10.13039/501100011033.M.M.-D.was recipient of PhD fellow(PRE2019-08812);funded by MCIN/AEI/10.13039/501100011033.E.G.-R;was supported by Autonomous Region of Madrid fellowship(S2017/BMD-3673);the European Commission-Next Generation EU(Regulation EU2020/2094)through CSIC’s Global Health Platform PTI Salud Global.; Beyond their function as structural barriers,plant cell walls are essential elements for the adaptation of plants to environmental conditions.Cell walls are dynamic structures whose composition and integrity can be al...; 关键词：Arabidopsis thaliana cell wall damage-associated molecular patterns DAMPS disease resistance GLYCANS OLIGOSACCHARIDES pattern-triggered immunity PTl pattern recognition receptor PRRs

Activation of autophagy by in situ Zn^(2+) chelation reaction for enhanced tumor chemoimmunotherapy被引量：3: 《Bioactive Materials》2023年第11期116-131,共16页Yang Yang Yefei Zhu Kairuo Wang Yunqiu Miao Yuanyuan Zhang Jie Gao Huanlong Qin Yang Zhang; the National Natural Science Foundation of China(Grant No.81730102,32271384);Shanghai Basic Research Program(Grant No.20JC1411702);Shanghai Science and Technology Program(Grant No.20ZR1456100).; Chemotherapy can induce a robust T cell antitumor immune response by triggering immunogenic cell death(ICD),a process in which tumor cells convert from nonimmunogenic to immunogenic forms.However,the antitumor immune ...; 关键词：CHEMOIMMUNOTHERAPY Immunogenic cell death(ICD) Damage-associated molecular patterns(DAMPs) Autophagy In situ chelation

基于Toll样受体通路与损伤相关分子模式分子炎症机制探讨扩张型心肌病中医药干预作用被引量：2: 《河北中医》2023年第10期1725-1727,1731,共4页李军姜春云解紫从王雪娇; 北京市中医药科技发展资金项目(编号:JJ-2020-69)。; 随着Toll样受体(TLRs)通路与损伤相关分子模式(DAMPs)分子炎症机制研究深入,其对炎性反应、自我免疫等人体生理代谢活动所需路径产生影响等证据表明,心肌炎性活动与此有关。炎症是防御机体内外病原造成组织损伤的主要机制。TLRs通路可...; 关键词：TOLL样受体 DAMPS 心肌病扩张型

Old and new damage‐associated molecular patterns (DAMPs) in autoimmune diseases: 《Rheumatology & Autoimmunity》2022年第4期185-197,共13页Na Kang Xiaohang Liu Kabeer Haneef Wanli Liu; The authors acknowledge support from the Tsinghua University Spring Breeze Fund,Center for Life Sciences,and Institute for Immunology,Tsinghua University,and grants from the Ministry of Science and Technology of China(2021YFC2300500 and 2021YFC2302403);National Natural Science Foundation of China(32141004,81825010,81730043,and 81621002).; All organisms living in complex environments have evolved effective mechanisms of dynamic responses to extracellular stimuli.The immune system activates when damaged or injured cells release damage‐associated molecul...; 关键词：autoimmune diseases damage‐associated molecular patterns farnesyl pyrophosphate geranylgeranyl diphosphate mevalonate pathway

植物激发子肽Peps的功能研究进展被引量：1: 《中国科学：生命科学》2022年第3期301-311,共11页荆彦平沈诺兰文智; 中国博士后科学基金面上项目(批准号:2020M673626XB)资助。; 植物危险相关分子模式(danger-associated molecular patterns, DAMPs)是一类植物体内合成并激活植物免疫的内源信号物质.近些年发现的植物激发子肽(plant elicitor peptides, Peps)是属于DAMPs类的小肽化合物,广泛分布于多种植物体内. ...; 关键词：植物免疫 DAMPS Peps PROPEPs PEPRs

RIG-I,a novel DAMPs sensor for myoglobin,activates NF-κB/caspase-3 signaling in CS-AKI model被引量：1: 《Military Medical Research》2022年第1期40-52,共13页Peng-Tao Wang Ning Li Xin-Yue Wang Jia-Le Chen Chen-Hao Geng Zi-Quan Liu Hao-Jun Fan Qi Lv Shi-Ke Hou Yan-Hua Gong; supported by the Tianjin UniversityaDouble First Classoconstruction talent start-up fund to Dr.Yan-Hua Gong,the grants awarded to Shi-Ke Hou by Science and Technology Commission of the CMC(c12019048);Ning Li by Open Fund of State Key Laboratory of Medicinal Chemical Biology(Nankai University)(2020010)。; Background:Acute kidney injury(AKI)is the main life-threatening complication of crush syndrome(CS),and myoglobin is accepted as the main pathogenic factor.The pattern recognition receptor retinoicacid-inducible gene I...; 关键词：Crush syndrome Acute kidney injury Retinoic acid-inducible gene I MYOGLOBIN Nuclear factor kappa-B/caspase-3 Damage-associated molecular patterns

Targeting whole body metabolism and mitochondrial bioenergetics in the drug development for Alzheimer’s disease被引量：6: 《Acta Pharmaceutica Sinica B》2022年第2期511-531,共21页Steven N.Austad Scott Ballinger Thomas W.Buford Christy S.Carter Daniel L.Smith Jr Victor Darley-Usmar Jianhua Zhang; the UAB NSC P30 AG05886(SA,SB,TB,CC,DLS,VDU,JZ)for partial support。; Aging is by far the most prominent risk factor for Alzheimer’s disease(AD),and both aging and AD are associated with apparent metabolic alterations.As developing effective therapeutic interventions to treat AD is cle...; 关键词：Mitochondrial DNA Mitochondrial electron transport chain Mitochondrial quality control Reactive species DAMPS Hexokinase biosynthesis pathway Diabetes Circadian regulation MICROBIOME

Gasdermin D in pyroptosis被引量：102: 《Acta Pharmaceutica Sinica B》2021年第9期2768-2782,共15页Brandon E.Burdette Ashley N.Esparza Hua Zhu Shanzhi Wang; supported by a grant from the National Institute of General Medical Sciences(P20 GM103429,USA);grants from National Heart,Lung and Blood Institute(HL153876,USA);National Eye Institute(EY030621,USA); Pyroptosis is the process of inflammatory cell death.The primary function of pyroptosis is to induce strong inflammatory responses that defend the host against microbe infection.Excessive pyroptosis,however,leads to s...; 关键词：PYROPTOSIS INFLAMMASOME CASPASE Gasdermin SEPSIS Inflammation Pathogen-associated molecular patterns(PAMPs) Damage-associated molecular patterns(DAMPs)

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