The phage anti-restriction induced system:new insights into bacterial immunity and bacteriophage escape strategies  

作　　者：Yi Zhong Volker M.Lauschke 

机构地区：[1]Department of Physiology and Pharmacology and Center of Molecular Medicine,Karolinska Institutet and Karolinska University Hospital,Stockholm,Sweden [2]Pharmaceutical Informatics Institute,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,Zhejiang,China [3]Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology,Stuttgart,Germany [4]Department of Pharmacy,the Second Xiangya Hospital,Central South University,Changsha,China

出　　处：《Signal Transduction and Targeted Therapy》2024年第11期4753-4754,共2页信号转导与靶向治疗（英文）

基　　金：funded by the Swedish Research Council[2021-02801 and 2023-03015];the Robert Bosch Foundation.

摘　　要：Two recent publications in Nature reveal the detailed structural mechanisms underlying the recognition of infection by the bacterial Phage Anti-Restriction Induced System(PARIS).1,2 These findings are important as they show a new strategy for the recognition of viral infections,shed light on principles of host-virus co-evolution and might pave the way for the development of new antimicrobial strategies.

关 键 词：IMMUNITY SYSTEM finding 

分 类 号：R392[医药卫生—免疫学]