丁苯酞治疗急性缺血性脑卒中后轻度血管性认知功能障碍的临床价值及意义  

Clinical Value and Significance of Butylphthalide in the Treatment of Mild Vascular Cognitive Dysfunction after Acute Ischemic Stroke

作　　者：祁延霞[1] QI Yan-xia(Qinghai Red Cross Hospital,Xining,Qinghai 810000)

机构地区：[1]青海红十字医院,青海西宁810000

出　　处：《智慧健康》2021年第29期130-132,共3页Smart Healthcare

摘　　要：目的丁苯酞治疗急性缺血性脑卒中后轻度血管性认知功能障碍的临床价值及意义。方法研究自医院抽取110例入院治疗急性缺血性脑卒中后轻度血管性认知功能障碍患者,时间为2020年2月至2021年2月,按照患者治疗中治疗方法的不同分为人数均等的两组(n=55),其中实施常规治疗为对照组,在常规治疗基础上实施丁苯酞为观察组,评估两组患者NIHSS、认知功能评分、临床疗效、MoCA评分并对比。结果治疗前两组患者NIHSS评分、MMSE评分差异小(P>0.05);治疗后与对照组相比,观察组NIHSS评分偏低、MMSE评分偏高(P<0.05)。与对照组相比,观察组疗效偏高(P<0.05)。治疗前两组患者视空间及执行能力、命名、注意力等项目的MoCA评分差异小(P>0.05);治疗后与对照组相比,观察组MoCA评分偏高(P<0.05)。结论对急性缺血性脑卒中后轻度血管性认知功能障碍患者使用丁苯酞治疗能够提高NIHSS评分,改善MoCA评分,增加认知功能障碍和神经障碍程度。Objective The clinical value and significance of butylphthalide in treating mild vascular cognitive impairment after acute ischemic stroke.Methods A total of 110 patients with mild vascular cognitive impairment after acute ischemic stroke from February 2020 to February 2021 were divided into two groups with equal numbers(n=55)according to different treatment methods,in which routine treatment was taken as the control group and butylphthalide was taken as the observation group on the basis of routine treatment.To evaluate and compare the two groups of patients with NIHSS,cognitive function score,clinical efficacy,and MoCA score.Results There was little difference in NIHSS score and MMSE score between the two groups before treatment(P>0.05).Compared with the control group after treatment,the observation group had a lower NIHSS score and a higher MMSE score(P<0.05).Compared with the control group,the curative effect of the observation group was higher(P<0.05).Before treatment,there was little difference in visual space,executive ability,naming and attention scores between the two groups(P>0.05).After treatment,compared with the control group,the score of MoCA in the observation group was higher and the curative effect was higher(P<0.05).Conclusion Butylphthalide can improve NIHSS score,improve MoCA score,and increase the degree of cognitive impairment and neurological impairment in patients with mild vascular cognitive impairment after acute ischemic stroke.

关 键 词：丁苯酞 急性缺血性脑卒中 轻度血管性 认知功能障碍 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R749.13[医药卫生—临床医学]