对干燥性角结膜炎给予普拉洛芬及聚乙烯醇的临床治疗评价  

Clinical Treatment Evaluation of Pranoprofen and Polyvinyl Alcohol for Dry Keratoconjunctivitis

作　　者：李晓萍 LI Xiao-ping(Zhongshan City Triangle Hospital,Zhongshan,Guangdong,528445)

机构地区：[1]中山市三角医院,广东中山528445

出　　处：《智慧健康》2020年第15期130-131,188,共3页Smart Healthcare

摘　　要：目的探析普拉洛芬及聚乙烯醇治疗干燥性角/结膜炎的临床效果。方法选取我院于2018年4月至2019年4月收治的50例干燥性角/结膜炎患者作为主要研究对象,采用数字随机表法将其分为对照组和观察组,各25例。对照组患者采用聚乙烯醇治疗,观察组患者采用普拉洛芬联合聚乙烯醇治疗,对两组患者的临床治疗效果、泪膜破裂时间、泪液分泌实验结果、主观症状评分进行对比分析。结果经对比两种治疗方法的有效性,观察组患者的治疗有效率显著高于对照组,两组对比有显著差异(P<0.05);观察组患者治疗后的主观症状评分小于对照组,两组比较有明显差异(P<0.05);两组患者治疗后的泪膜破裂时间、泪液分泌实验结果均大于治疗前,且观察组患者的泪膜破裂时间、泪液分泌实验结果大于对照组,差异有统计学意义。结论在干燥性角/结膜炎的临床治疗上,采用普拉洛芬联合聚乙烯醇治疗的疗效显著,可改善患者的临床症状,值得在临床上进一步推广和应用。Objective To explore clinical effect of praprofen and polyvinyl alcohol in treatment of dry keratoconjunctivitis.Methods Choose 50 cases keratoconjunctivitis sicca patients from April 2018 to April 2019 as main research objects,and divide them into control group and observation group with random digital table method,25 cases in each group.Control group was treated with polyvinyl alcohol,and observation group with pranoprofen combined with polyvinyl alcohol.Compare and analyze clinical treatment effects,tear film rupture time,tear secretion test results,and subjective symptom scores of two groups.Results Comparing effectiveness of two treatment methods,treatment effect of observation group was significantly higher than control group,with significant difference between two groups(P<0.05);subjective symptom scores of observation group after treatment were lower than control group,with significant difference between two groups(P<0.05);tear film rupture time and tear secretion test results of two groups were greater than before treatment,and tear film rupture time and tear secretion test results of observation group were better than control group,difference was statistically significant.Conclusion Conservative treatment with pranoprofen combined with polyvinyl alcohol has significant effect during clinical treatment of keratoconjunctivitis sicca,can improve clinical symptoms of patients,which is worthy of further promotion and application in clinical practice.

关 键 词：普拉洛芬 聚乙烯醇 干燥性角/结膜炎 治疗效果 

分 类 号：R777.31[医药卫生—眼科] R772.21[医药卫生—临床医学]