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医药卫生—眼科: 作品数：208511被引量：190131H指数：97; 导出分析报告; 相关作者：惠延年王宁利邢怡桥毕宏生谢立信更多>>; 相关机构：首都医科大学中山大学复旦大学爱尔眼科医院更多>>; 发文主题：白内障青光眼近视疗效观察儿童更多>>; 相关期刊：更多>>; 发文基金：国家自然科学基金广东省自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>

Single-cell RNA sequencing reveals the heterogeneity and interactions of immune cells and Müller glia during zebrafish retina regeneration: 《Neural Regeneration Research》2025年第12期3635-3648,共14页Hui Xu Lining Cao Yuxi Chen Cuiping Zhou Jie Xu Zhuolin Zhang Xiangyu Li Lihua Liu Jianfeng Lu; supported by the National Natural Science Foundation of China,Nos.81970820(to HX),31771644(to JL),31930068(to JL),82371176(to JL),81801331(to LC);National Key Research and Development Project of China.Nos.2017YFA0104100(to JL),2017YFA0701304(to HX);Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center)Talent Introduction Plan,No.KYPT202204(to LC);the Fundamental Research Funds for the Central Universities,No.22120230292(to JL)。; Inflammation plays a crucial role in the regeneration of fish and avian retinas.However,how inflammation regulates Müller glia(MG)reprogramming remains unclear.Here,we used single-cell RNA sequencing to investigate t...; 关键词：immune cells inflammation Jak1-Stat3 signaling microglia Müller glia REGENERATION reprogramming RETINA single-cell RNAseq ZEBRAFISH

Mitochondrial transplantation:a promising strategy for the treatment of retinal degenerative diseases: 《Neural Regeneration Research》2025年第12期3370-3387,共18页Jing Chi Bin Fan Yulin Li Qing Jiao Guang-Yu Li; supported by the National Natural Science Foundation of China,Nos.8247041526,81570864,82171053(to GYL)。; The retina,a crucial neural tissue,is responsible for transforming light signals into visual information,a process that necessitates a significant amount of energy.Mitochondria,the primary powerhouses of the cell,play...; 关键词：age-related macular degeneration Leber’s hereditary optic neuropathy mitochondrial transfer mitochondrial transplantation retinal degenerative diseases

Potential of ultrasound stimulation and sonogenetics in vision restoration:a narrative review: 《Neural Regeneration Research》2025年第12期3501-3516,共16页Jie Ji Chen Gong Gengxi Lu Junhang Zhang Baoqiang Liu Xunan Liu Junhao Lin Patrick Wang Biju B.Thomas Mark S.Humayun Qifa Zhou; supported by R01EY032229(Biomechanical Mapping of the Optic Nerve Head and Peripapillary Sclera Using High Frequency Ultrasonic Elastography);R01EY028662(High-resolution Elastographic Assessment of the Optic Nerve Head);R01EY030126(Non-invasive Ultrasound Stimulated Retinal Prosthesis)(to QZ);Unrestricted Grant to the Department of Ophthalmology from Research to Prevent Blindness,New York,NY(to MSH);the National Eye Institute of the National Institutes of Health under Award Number P30EY029220(to MSH)。; Vision restoration presents a considerable challenge in the realm of regenerative medicine,while recent progress in ultrasound stimulation has displayed potential as a non-invasive therapeutic approach.This narrative ...; 关键词：NEUROMODULATION NON-INVASIVE optic nerve injury retinal degeneration sonogenetics ultrasound stimulation visual restoration

Bidirectional causality of physical exercise in retinal neuroprotection: 《Neural Regeneration Research》2025年第12期3400-3415,共16页Stephen K.Agadagba Suk-yu Yau Ying Liang Kristine Dalton Benjamin Thompson; supported by the InnoHK Initiative and the Hong Kong Special Administrative Region Government, China (to SYY)。; Physical exercise is recognized as an effective intervention to improve mood,physical performance,and general well-being.It achieves these benefits through cellular and molecular mechanisms that promote the release of...; 关键词：age-related macular degeneration biomarkers diabetic retinopathy GLAUCOMA neuroprotective factors ocular diseases physical exercise retinal neuroprotection retinitis pigmentosa visual impairment

AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis: 《Neural Regeneration Research》2025年第8期2408-2419,共12页Ruiqi Qiu Mingzhu Yang Xiuxiu Jin Jingyang Liu Weiping Wang Xiaoli Zhang Jinfeng Han Bo Lei; supported by the National Natural Science Foundation of China,Nos.82071008(to BL)and 82004001(to XJ);Medical Science and Technology Program of Health Commission of Henan Province,No.LHGJ20210072(to RQ);Science and Technology Department of Henan Province,No.212102310307(to XJ)。; Retinitis pigmentosa is a group of inherited diseases that lead to retinal degeneration and photoreceptor cell death.However,there is no effective treatment for retinitis pigmentosa caused by PDE6B mutation.Adeno-asso...; 关键词：APOPTOSIS AAV2-PDE6B ERK1/2 gene therapy PHOTOTRANSDUCTION PROTEOMICS rd10 retinitis pigmentosa

雷珠单抗玻璃体内注射联合和血明目片在湿性老年性黄斑变性患者中的应用价值: 《黑龙江医药科学》2025年第3期65-67,71,共4页吴瑞婵潘俊辉陈志毅; 河南省医学科技攻关计划联合共建项目,编号:LHGJ20201006。; 目的:探讨雷珠单抗玻璃体内注射联合和血明目片在湿性老年性黄斑变性(SMD)患者中的应用价值。方法:选取2022年1月至2023年10月新郑华信民生医院收治的湿性SMD患者84例,随机数字表法分为雷珠单抗组与和血明目片联合组,各42例。雷珠单抗...; 关键词：和血明目片雷珠单抗湿性老年性黄斑变性血液流变学血管内皮功能

Apolipoprotein A-I binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration: 《Neural Regeneration Research》2025年第5期1414-1415,共2页Sinwoo Hwang Seunghwan Choi Soo-Ho Choi Keun-Young Kim Yury I.Miller Won-Kyu Ju; supported by the National Institutes of Health grants EY034116 (to WKJ, KYK, and SHC) and AG081037 (to YIM and WKJ)。; Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs worldwide.Due to the aging population,it is expected that the number of peopl...; 关键词：IRREVERSIBLE PASS primarily

2024版《中国科技期刊引证报告》核心版眼科期刊主要指标及排名: 《国际眼科杂志》2025年第4期564-564,共1页

再生医学在创伤性视神经损伤修复中的应用研究进展: 《新乡医学院学报》2025年第4期253-259,共7页田林强王磊刘晓谭任文杰苏国辉; 国家自然科学基金面上项目(编号:80471191);国家重点研发计划项目(编号:2024YFA1107804)。; 创伤性视神经损伤通常由直接或间接的机械损伤引起,影响视神经及其相关结构,从而导致视网膜神经节细胞死亡,目前尚无标准的治疗方案。再生医学作为一种有前景的损伤修复手段,逐渐引起了科学界的广泛关注。现有研究表明,再生医学在视神...; 关键词：创伤性视神经损伤干细胞神经炎症轴突再生再生医学

眼科生物参数测量仪自动对准及对焦方法: 《佛山科学技术学院学报(自然科学版)》2025年第2期37-42,共6页刘桐生曾亚光何志敏; 广东省自然科学基金资助项目(2022A1515140116)。; 为了解决现有眼科生物参数测量仪对准对焦速度慢、精度低和普适性差的问题,提出了基于灰度能量曲线的光轴中心自动对准算法以及基于决策树的自动对焦算法。首先,对仪器实拍的人眼图像进行局部区域高斯模糊预处理,再利用行和列方向的灰...; 关键词：自动对准自动对焦中心定位灰度能量曲线决策树图像处理眼科医疗设备

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