医药卫生—眼科

作品数：209979被引量：190519H指数：97
导出分析报告
相关作者：惠延年王宁利邢怡桥毕宏生谢立信更多>>
相关机构：首都医科大学中山大学复旦大学爱尔眼科医院更多>>
发文主题：白内障青光眼近视疗效观察儿童更多>>
相关期刊：更多>>
发文基金：国家自然科学基金广东省自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Innovative gene delivery systems for retinal disease therapy
《Neural Regeneration Research》2026年第2期542-552,共11页Hongguang Wu Ling Dong Shibo Jin Yongwang Zhao Lili Zhu 
Hongguang Wu,Both authors contributed equally to this work and share first authorship;Ling Dong,Both authors contributed equally to this work and share first authorship;。
The human retina,a complex and highly specialized structure,includes multiple cell types that work synergistically to generate and transmit visual signals.However,genetic predisposition or age-related degeneration can...
关键词：adeno-associated viruses delivery systems gene delivery gene therapy LENTIVIRUS nanoparticle delivery non-viral delivery retinal disease RETINA small molecular delivery 
Targeting Wallerian degeneration in glaucoma
《Neural Regeneration Research》2026年第2期693-694,共2页Melissa Jöe Pete A.Williams 
supported by St.Erik Eye Hospital philanthropic donations,Vetenskapsrådet 2022-00799(to PAW).
Neurodegenerative diseases account for a large and increasing health and economic burden worldwide.With an increasingly aged population,this burden is set to increase.Optic neuropathies make up a large proportion of n...
关键词：health burden neurodegenerative diseases aged population Wallerian degeneration GLAUCOMA vision loss economic burden retinal ganglion cells their axons 
Topical administration of GLP-1 eyedrops improves retinal ganglion cell function by facilitating presynaptic GABA release in early experimental diabetes
《Neural Regeneration Research》2026年第2期800-810,共11页Yu-Qi Shao Yong-Chen Wang Lu Wang Hang-Ze Ruan Yun-Feng Liu Ti-Hui Zhang Shi-Jun Weng Xiong-Li Yang Yong-Mei Zhong 
supported by the National Natural Science Foundation of China,Nos.32070989(to YMZ),31872766(to YMZ),81790640(to XLY),and 82070993(to SJW);the grant from Sanming Project of Medicine in Shenzhen,No.SZSM202011015(to XLY)。
Diabetic retinopathy is a prominent cause of blindness in adults,with early retinal ganglion cell loss contributing to visual dysfunction or blindness.In the brain,defects inγ-aminobutyric acid synaptic transmission ...
关键词：diabetic retinopathy glucagon-like peptide-1 inhibitory synaptic transmission miniature inhibitory postsynaptic currents NEURODEGENERATION NEUROPROTECTION patch-clamp recording protein kinase C signaling pathway visual function 
Mesenchymal stem cell-derived small extracellular vesicles enhance the therapeutic effect of retinal progenitor cells in retinal degenerative disease rats
《Neural Regeneration Research》2026年第2期821-832,共12页Chunge Ren Min Chen Bangqi Ren Yuxiao Zeng Qiang Tan Qiyou Li Xue Zhang Yajie Fang Yixiao Zhou Weitao Zhang Fang Chen Baishijiao Bian Yong Liu 
supported by the National Natural Science Foundation of China,Nos.82271132(to YL),82101167(to BB);the Natural Science Foundation of Chongqing,Nos.CSTB2022NSCQ-MSX0020(to BB),cstc2019jcyj-msxmX0473(to FC).
Our previous study demonstrated that combined transplantation of bone marrow mesenchymal stem cells and retinal progenitor cells in rats has therapeutic effects on retinal degeneration that are superior to transplanta...
关键词：DIFFERENTIATION inflammation mesenchymal stem cells MICROGLIA migration rat retinal degeneration retinal progenitor cells small extracellular vesicles stem cell transplantation 
Single-cell RNA sequencing reveals the heterogeneity and interactions of immune cells and Müller glia during zebrafish retina regeneration
《Neural Regeneration Research》2025年第12期3635-3648,共14页Hui Xu Lining Cao Yuxi Chen Cuiping Zhou Jie Xu Zhuolin Zhang Xiangyu Li Lihua Liu Jianfeng Lu 
supported by the National Natural Science Foundation of China,Nos.81970820(to HX),31771644(to JL),31930068(to JL),82371176(to JL),81801331(to LC);National Key Research and Development Project of China.Nos.2017YFA0104100(to JL),2017YFA0701304(to HX);Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center)Talent Introduction Plan,No.KYPT202204(to LC);the Fundamental Research Funds for the Central Universities,No.22120230292(to JL)。
Inflammation plays a crucial role in the regeneration of fish and avian retinas.However,how inflammation regulates Müller glia(MG)reprogramming remains unclear.Here,we used single-cell RNA sequencing to investigate t...
关键词：immune cells inflammation Jak1-Stat3 signaling microglia Müller glia REGENERATION reprogramming RETINA single-cell RNAseq ZEBRAFISH 
Mitochondrial transplantation:a promising strategy for the treatment of retinal degenerative diseases
《Neural Regeneration Research》2025年第12期3370-3387,共18页Jing Chi Bin Fan Yulin Li Qing Jiao Guang-Yu Li 
supported by the National Natural Science Foundation of China,Nos.8247041526,81570864,82171053(to GYL)。
The retina,a crucial neural tissue,is responsible for transforming light signals into visual information,a process that necessitates a significant amount of energy.Mitochondria,the primary powerhouses of the cell,play...
关键词：age-related macular degeneration Leber’s hereditary optic neuropathy mitochondrial transfer mitochondrial transplantation retinal degenerative diseases 
Potential of ultrasound stimulation and sonogenetics in vision restoration:a narrative review
《Neural Regeneration Research》2025年第12期3501-3516,共16页Jie Ji Chen Gong Gengxi Lu Junhang Zhang Baoqiang Liu Xunan Liu Junhao Lin Patrick Wang Biju B.Thomas Mark S.Humayun Qifa Zhou 
supported by R01EY032229(Biomechanical Mapping of the Optic Nerve Head and Peripapillary Sclera Using High Frequency Ultrasonic Elastography);R01EY028662(High-resolution Elastographic Assessment of the Optic Nerve Head);R01EY030126(Non-invasive Ultrasound Stimulated Retinal Prosthesis)(to QZ);Unrestricted Grant to the Department of Ophthalmology from Research to Prevent Blindness,New York,NY(to MSH);the National Eye Institute of the National Institutes of Health under Award Number P30EY029220(to MSH)。
Vision restoration presents a considerable challenge in the realm of regenerative medicine,while recent progress in ultrasound stimulation has displayed potential as a non-invasive therapeutic approach.This narrative ...
关键词：NEUROMODULATION NON-INVASIVE optic nerve injury retinal degeneration sonogenetics ultrasound stimulation visual restoration 
Bidirectional causality of physical exercise in retinal neuroprotection
《Neural Regeneration Research》2025年第12期3400-3415,共16页Stephen K.Agadagba Suk-yu Yau Ying Liang Kristine Dalton Benjamin Thompson 
supported by the InnoHK Initiative and the Hong Kong Special Administrative Region Government, China (to SYY)。
Physical exercise is recognized as an effective intervention to improve mood,physical performance,and general well-being.It achieves these benefits through cellular and molecular mechanisms that promote the release of...
关键词：age-related macular degeneration biomarkers diabetic retinopathy GLAUCOMA neuroprotective factors ocular diseases physical exercise retinal neuroprotection retinitis pigmentosa visual impairment 
AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis
《Neural Regeneration Research》2025年第8期2408-2419,共12页Ruiqi Qiu Mingzhu Yang Xiuxiu Jin Jingyang Liu Weiping Wang Xiaoli Zhang Jinfeng Han Bo Lei 
supported by the National Natural Science Foundation of China,Nos.82071008(to BL)and 82004001(to XJ);Medical Science and Technology Program of Health Commission of Henan Province,No.LHGJ20210072(to RQ);Science and Technology Department of Henan Province,No.212102310307(to XJ)。
Retinitis pigmentosa is a group of inherited diseases that lead to retinal degeneration and photoreceptor cell death.However,there is no effective treatment for retinitis pigmentosa caused by PDE6B mutation.Adeno-asso...
关键词：APOPTOSIS AAV2-PDE6B ERK1/2 gene therapy PHOTOTRANSDUCTION PROTEOMICS rd10 retinitis pigmentosa 
Effects of modified Yokoyama surgery combined with medial rectus muscle recession on esotropia in highly myopia athletes
《World Journal of Clinical Cases》2025年第21期34-41,共8页Zi-Yang He Tan Cui Zhi-Qi Cui Hui-Xia Yan Mei-Xuan Chen Hao Luo 
BACKGROUND Fixed esotropia in high myopia,characterized by irreversible inward ocular deviation and abduction limitation,presents unique therapeutic challenges for athletes requiring precise binocular coordination.The...
关键词：High myopia with fixed esotropia ATHLETE Eye movement Modified Yokoyama surgery Medial rectus muscle recession 
全选清除导出
共20,901页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部