乳腺肌纤维母细胞性肿瘤及瘤样病变临床病理分析  

Clinicopathologic features of myofibroblastic tumors and tumor-like lesions of breast

作　　者：魏胜男 吴文亚 苏雅洁 WEI Sheng-nan;WU Wen-ya;SU Ya-jie(Department of Pathology,Shunyi Maternal and Children’s Hospital of Beijing Children’s Hospital,Beijing 101300,China)

机构地区：[1]北京市顺义区妇幼保健院,北京儿童医院顺义妇儿医院病理科,北京101300

出　　处：《诊断病理学杂志》2023年第12期1084-1088,共5页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨乳腺肌纤维母细胞性肿瘤及瘤样病变的临床病理特征、免疫表型特点、诊断及鉴别诊断。方法收集北京儿童医院顺义妇儿医院2016-10—2023-02诊断的6例乳腺肌纤维母细胞性肿瘤及瘤样病变,分析其临床表现、病理组织学特征、免疫组化特点,并复习相关文献。结果6例患者均为女性,年龄范围26~75岁;1例为孤立性纤维性肿瘤,1例为肌纤维母细胞瘤,1例为低级别肌纤维母细胞肉瘤,1例为结节性筋膜炎,2例为损伤后反应性改变。结论乳腺肌纤维母细胞性肿瘤及瘤样病变是乳腺较为罕见的病变,结合病史、病理组织学形态及免疫表型等综合分析,可以有效减少误诊和漏诊。Objective To investigate the clinicopathological features,immunophenotypic features,diagnosis and differential diagnosis of breast myofibroblastic tumors and tumor-like lesions.Methods Six cases of breast myofibroblastic tumors and tumor-like lesions diagnosed in Shunyi Maternal and Children’s Hospital of Beijing Children’s Hospital from October 2016 to February 2023 were collected.The clinical manifestations,histopathological features and immunohistochemical characteristics were analyzed,and relevant literatures were reviewed.Results All the 6 patients were female,ranged in age from 26 to 75 years.One case was solitary fibrous tumor,1 case was myofibroblastoma,1 case was low-grade myofibroblastic sarcoma,1 case was nodular fasciitis,and 2 cases were posttraumatic reactivity change.Conclusion Breast myofibroblastic tumors and tumor-like lesions are relatively rare lesions of the breast.Combined with the comprehensive analysis of medical history,histopathological morphology and immunophenotype,misdiagnosis and missed diagnosis can be effectively reduced.

关 键 词：乳腺 肌纤维母细胞性肿瘤 瘤样病变 免疫组化 

分 类 号：R737.9[医药卫生—肿瘤]