中草药提取物辅助降尿酸功效研究  

Efficacy of Chinese herb extracts for auxiliary reducing uric acid

作　　者：尹晓晨[1] 颜娜 龙晓蕾[1] 胡余明[1] YIN Xiao-chen;YAN Na;LONG Xiao-lei;HU Yu-ming(Hunan Provincial Center for Disease Control and Prevention,Changsha,Hunan 410005,China;Hunan Branch of China Southern Airlines Co.,Ltd.,Changsha,Hunan 410000,China)

机构地区：[1]湖南省疾病预防控制中心,湖南长沙410005 [2]中国南方航空股份有限公司湖南分公司,湖南长沙410000

出　　处：《实用预防医学》2022年第1期51-54,共4页Practical Preventive Medicine

基　　金：湖南省卫生健康委科研计划课题项目(B20190040)

摘　　要：目的了解某中草药提取物对高尿酸血症的辅助改善效果。方法对高尿酸血症人群进行某中草药提取物干预,对干预前后试食组和对照组人群进行血清尿酸值、相关安全性指标及中医临床症状比较。结果试食前后二组受试者的体重、血压、心率、血尿便常规及生化指标差异均无统计学意义(均P>0.05),且均在正常范围内,该中草药提取物对人体健康无损害作用。试食组试食后血清尿酸值(383.00±83.61)mol/L与试食前自身(472.01±62.85)mol/L比较及与对照组试食后(461.72±88.02)mol/L比较,均有显著降低(P<0.01),试食后试食组血清尿酸下降有效率(18.86%)显著高于对照组(2.56%)(P<0.05),试食组中医临床症状积分(3.96±1.59)显著低于自身试验前(5.12±2.65)及对照组试验后(5.02±2.43)(P<0.05)。结论本研究中草药提取物在辅助人群降尿酸功效上具有良好的改善作用,对人群健康无明显危害。Objective To investigate the auxiliary improvement effect of Chinese herb extracts on hyperuricemia.Methods Patients with hyperuricemia received an intervention with Chinese herbal extracts,and the serum uric acid value,related safety indicators and clinical symptoms of traditional Chinese medicine were compared between the eating trial group and the control group before and after the intervention.Results No statistically significant differences were found in body weight,blood pressure,heart rate,blood routine,urine routine,stool routine and biochemical indexes between the two groups before and after the trial(all P>0.05),and all of them were within the normal range.No adverse effect on health was observed in the Chinese herb extracts.The serum uric acid value of the trial group after the trial((383.00±83.61)mol/L)significantly decreased(P<0.01)as compared with that of the trial group before the trial((472.01±62.85)mol/L)and that of the control group after the trial((461.72±88.02)mol/L).The effective rate of reducing uric acid in the trial group after the trial was significantly higher than that in the control group(18.86%vs.2.56%,P<0.05).The clinical symptom integral of traditional Chinese medicine in the trial group after the trial(3.96±1.59)was significantly lower than that of the trial group before the trial(5.12±2.65)as well as that of the control group after the trial(5.02±2.43)(both P<0.05).Conclusion The Chinese herb extracts can significantly improve the efficacy of auxiliary reducing uric acid in the population and has no obvious harm to human health.

关 键 词：高尿酸血症 中草药提取物 改善作用 泽泻 菊苣 车前草 

分 类 号：R589.7[医药卫生—内分泌]