皮损大部切除术及全厚皮片移植术成功治疗先天性丛状血管瘤一例并文献复习  

Subtotal skin resection and full-thickness skin grafting successfully treated one case of congenital tufted angioma and literature review

作　　者：董丽萍 朱飞[2] 陈竹 蔡新颖[1] 肖风丽[1] DONG Li-ping;ZHU Fei;CHEN Zhu(Department of Dermatology,the First Affiliated Hospital,and Institute of Dermatology,Anhui Medical University,Hefei 230032,China)

机构地区：[1]安徽医科大学第一附属医院皮肤性病科·安徽医科大学皮肤病研究所,合肥230032 [2]安徽医科大学第一附属医院整形外科

出　　处：《实用皮肤病学杂志》2023年第4期206-209,共4页Journal of Practical Dermatology

基　　金：国家自然科学基金资助项目(81972926)

摘　　要：49岁男性患者,左腋窝后侧红褐色斑片、结节49年,伴疼痛40余年。皮肤科情况:左腋窝后侧背部可见一20 cm×12 cm大小的暗红色斑片,上有数个粟粒至黄豆大小暗红色结节,局部有浸润感,边界不清,按压时疼痛加重,压之不褪色。组织病理示:真皮内多个小的毛细血管增生性结节,管腔呈“炮弹”状分布;免疫组化染色示CD34、CD31、FLi-1、F8均(+),Ki-67(1%+)。诊断:先天性丛状血管瘤。治疗:局部注射聚桂醇2次后,行皮损大部切除术和全厚皮片移植术。术后2个月移植皮片生长良好,疼痛消失,目前仍在随访中。结合该例对近10年国内外报道的108例丛状血管瘤患者临床资料进行复习。A 49-year-old male patient present with reddish-brown patches on the posterior side of the left armpit,nodules for 49 years,with pain for more than 40 years.Dermatology examination:a 20 cm×12 cm flaky dark red patch was visible on the back of the left armpit.There were several dark red nodules the size of miliary grains to soybeans.There was a sense of local infiltration and the boundary was unclear.The pain was aggravated and it could not fade when pressed.Histopathology showed multiple small capillary hyperplasia nodules in the dermis,and the small lumen showed a“canonball”distribution.Immunohistochemistry:CD34(+),CD31(+),FLi-1(+),F8(+),Ki-67(1%+).Congenital tufted angioma.Treatment:After two local injections of polidocanol,a partial skin lesion resection and full-thickness skin grafting were performed.The grafted skin grafts grew well two months after the operation,and the pain disappeared.The patient was still being a clinical data of 108 cases of tufted angioma with complete data published at home and abroad in the past 10 years are summarized.

关 键 词：血管瘤 丛状 临床表现 组织病理 外科切除术 全厚皮片术移植术 

分 类 号：R732.23[医药卫生—肿瘤]