半夏泻心汤加减敷脐联合西医常规疗法治疗急性十二指肠溃疡出血的临床观察  

Clinical observation on umbilical compress therapy of modified Banxia Xiexin Decoction combined with conventional western medicine in treatment of acute duodenal ulcer bleeding

作　　者：黎林[1] 王倩[1] 韩丹[1] 凌琪华[1] LI Lin;WANG Qian;HAN Dan;LING Qihua(Department of Emergency Medicine,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海中医药大学附属曙光医院急诊内科,上海201203

出　　处：《上海中医药大学学报》2022年第S01期12-15,共4页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(82074156,82004321);上海市“科技创新行动计划”医学创新研究专项项目(20Y21900300,21Y11920500)

摘　　要：目的:观察半夏泻心汤加减敷脐联合西医常规疗法治疗急性胃十二指肠溃疡出血的临床疗效。方法:将90例急性十二指肠溃疡出血患者随机分为对照组和治疗组,每组45例。对照组患者给予西医常规治疗,治疗组在对照组治疗措施的基础上联合使用半夏泻心汤加减敷脐疗法,疗程为5 d。观察临床疗效,比较大便隐血转阴时间、禁食时间、住院时间,以及中医证候积分、血红蛋白水平、血尿素氮水平的变化情况。结果:①治疗组显效率、有效率、总证候积分改善率高于对照组(P<0.05)。②治疗组大便隐血转阴时间早于对照组,禁食时间短于对照组(P<0.05)。两组住院天数比较,差异无统计学意义(P>0.05)。③治疗后,两组血红蛋白、尿素氮水平均得到改善(P<0.05),治疗组的改善情况优于对照组(P<0.05)。结论:与单纯采用西医常规治疗相比,半夏泻心汤加减敷脐疗法联合西医常规治疗对急性十二指肠溃疡出血疗效满意,可在临床推广使用。Objective:To observe the clinical efficacy of umbilical compress therapy of modified Banxia Xiexin Decoction combined with conventional western medicine in the treatment of acute duodenal ulcer bleeding.Methods:Ninety patients of acute duodenal ulcer bleeding were randomly divided into the control group and treatment group,45 cases in each group.The patients in the control group were treated with conventional western medicine,and the patients in the treatment group were treated with umbilical compress therapy of modified Banxia Xiexin Decoction based on the treatment for the control group,with a course of 5 days.The clinical efficacy was observed,and the changes of turning negative time of fecal occult blood,fasting time,hospital stay,traditional Chinese medicine syndrome score,hemoglobin level and blood urea nitrogen level were compared.Results:①The apparent effective rate,effective rate and improvement rate of total syndrome score in the treatment group were higher than those in the control group(P<0.05).②The turning negative time of fecal occult blood in the treatment group was earlier than that in the control group,and the fasting time was shorter than that in the control group(P<0.05).There was no statistically significant difference in the hospital stay between the two groups(P>0.05).③After treatment,the levels of hemoglobin and urea nitrogen in both groups were improved(P<0.05),and the improvement in the treatment group was better than that in the control group(P<0.05).Conclusion:Compared with conventional western medicine alone,umbilical compress therapy of modified Banxia Xiexin Decoction combined with conventional western medicine shows good efficacy in the treatment of acute duodenal ulcer bleeding,which can be widely used in clinic.

关 键 词：十二指肠溃疡出血 急性 半夏泻心汤 敷脐疗法 

分 类 号：R573.1[医药卫生—消化系统]