4526例开放性眼外伤流行病学特点及预后因素影响分析  

Epidemiological characteristics and prognostic factors associated with 4526 cases of open globe injuries:a retrospective study

作　　者：付庆毓 刘添添 王平平 刘陇黔[1] FU Qingyu;LIU Tiantian;WANG Pingping;LIU Longqian(Department of Ophthalmology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China)

机构地区：[1]四川大学华西医院眼科,四川成都610041

出　　处：《山东大学耳鼻喉眼学报》2024年第2期26-33,共8页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：四川省科技厅项目(21ZDYF1415);美国中华医学基金会应用技术项目(0040205502017)

摘　　要：目的探讨开放性眼外伤(open globe injury,OGI)流行病学特点和预后影响因素。方法对四川大学华西医院2009年1月至2020年12月间4526例OGI患者进行回顾性研究,对患者的一般情况、致伤原因、并发症、受伤后就诊时间等因素对出院视力的影响进行单因素分析,对差异具有统计学意义的单因素进一步采用多因素二元Logistic回归模型进行分析。结果多因素二元Logistic回归分析显示,少数民族、(45,60)岁、(60,75)岁、钝物致伤、摔倒致伤、再次入院、住院时间延长、合并球内出血、晶状体脱位和眶骨骨折是出院视力<0.05的危险因素(OR=1.355,1.380,2.387,1.716,1.601,2.013,1.889,1.983,1.857,3.311;95%CI=1.050~1.748,1.140~1.670,1.632~3.490,1.290~2.282,1.066~2.403,1.668~2.429,1.581~2.258,1.627~2.417,1.351~2.553,2.109~5.198;P均<0.05)。结论OGI以中青年男性为主,致伤因素多与工作场所相关,视力预后差,应开展具有针对的预防干预措施。Objective To study the epidemiological features and prognostic factors of open globe injuries(OGI).Methods A retrospective study was conducted,focusing on OGI treated at West China Hospital,Sichuan University,between January 2009 and December 2020.Univariate analysis was used to determine the impact of various factors,including general patient information,causes of injury,complications,and the interval between injury and presentation to the hospital,on the visual outcomes at discharge.Factors that showed statistically significant differences were further analyzed using a multivariate binary Logistic regression model.Results Multivariate binary Logistic regression analysis revealed that,ethnic minorities,age groups of(45,60)years,age groups of(60,75)years,blunt object resulting in injury,falls resulting in injury,rehospitalization,prolonged hospital stay,complications included intraocular hemorrhage,dislocated lens,and orbital fractures are risk factors for discharge visual acuity<0.05(OR=1.355,1.380,2.387,1.716,1.601,2.013,1.889,1.983,1.857,3.311;95%CI=1.050-1.748,1.140-1.670,1.632-3.490,1.290-2.282,1.066-2.403,1.668-2.429,1.581-2.258,1.627-2.417,1.351-2.553,2.109-5.198;all P<0.05).Conclusion OGI predominantly affect young and middle-aged males,with many injuries related to the workplace.Visual prognosis of OGI is generally poor,emphasizing the need for targeted preventive interventions.

关 键 词：开放性眼外伤 眼球破裂伤 机械性眼外伤 球内出血 晶状体脱位 眶骨骨折 

分 类 号：R779.1[医药卫生—眼科]