膀胱癌术后应用消癥肾气汤结合中医埋针治疗效果评价  

Efficacy Evaluation of Xiaozheng Shenqi Decoction Combined with Traditional Chinese Medicine Needle Embedding for Post-operation of Bladder Cancer

作　　者：胡小丽[1] HU Xiaoli(Nantong Municipal Hospital of Traditional Chinese Medicine,Nantong Jiangsu 226000,China)

机构地区：[1]南通市中医院,江苏南通226000

出　　处：《四川中医》2022年第9期141-144,共4页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:探究膀胱癌术后应欲消癥肾气汤结合中医埋针治疗效果。方法:纳入98例膀胱癌患者(2019年1月~2020年4月收治),将患者以随机数字表法分为对照组与观察组,各49例;对照组患者采取经尿道电切术+丝裂霉素灌注治疗,观察组经尿道电切术+丝裂霉素灌注并联合消癥肾气汤及中医埋针治疗,数据比较:疗效及并发症、治疗前后中医证候积分(尿频尿急尿痛、排尿困难、腰酸、肢体逆冷等)及血清肿瘤坏死因子α(TNF-α)水平变化、免疫功能指标变化及生活质量(QLQ-BLM30)评分变化,随访1年,比较患者1年癌症复发率。结果:与对照组患者相比(63.27%)、(16.33%),观察组有效率(81.63%)更高,并发症率(2.04%%)更低(P<0.05);治疗前,两组患者中医证候积分(尿频尿急尿痛、排尿困难、腰酸、肢体逆冷等)、TNF-α水平、CD4^(+)、CD8^(+)、QLQ-BLM30评分等指标比较无显著性差异(P>0.05);治疗后各组患者中医证候积分(尿频尿急尿痛、排尿困难、腰酸、肢体逆冷等)、TNF-α水平、CD4^(+)、CD8^(+)、QLQ-BLM30评分等指标均改善,观察组患者治疗后中医证候积分(尿频尿急尿痛、排尿困难、腰酸、肢体逆冷等)、TNF-α水平、CD4^(+)、CD8^(+)、QLQ-BLM30评分等指标优于对照组(P<0.05);1年后随访显示观察组患者复发率低于对照组(P<0.05)。结论:膀胱癌术后应用消癥肾气汤结合中医埋针治疗效果佳,患者免疫功能及生活质量提升,1年复发率降低,安全可靠。Objective:To explore the efficacy of using Xiaozheng Shenqi Decoction combined with traditional Chinese medicine needle embedding in the treatment of bladder cancer.Methods:A total of 98 patients with bladder cancer(admitted from January 2019 to April 2020)were enrolled and divided into a controlled group and an observation group by the random number table method,with 49 cases in each group.The controlled group was treated with transurethral resection+mitomycin infusion,while the observation group was treated with transurethral resection+mitomycin infusion combined with Xiaozheng Shenqi Decoction and traditional Chinese medicine needle embedding.Data comparison:Efficacy and complications,TCM syndrome scores(frequency of urination,pain of urination,dysuria,lumbar acid,limb retrocoldness,etc.),changes in serum tumor necrosis factorα(TNF-α)level,changes in immune function indexes and quality of life(QLQ-BLM30)score before and after treatment.Patients were followed up for 1 year,and cancer recurrence rate of 1 year was compared.Results:Compared with the controlled group(63.27%)and(16.33%),the effective rate of the observation group(81.63%)was higher,and the complication rate(2.04%)was lower,P<0.05.Before treatment,the scores of TCM syndrome(frequency of urination,pain of urination,dysuria,lumbar acid,limb retrocoldness,etc.),TNF-αlevel,CD4^(+),CD8^(+),QLQ-BLM30 score and other indicators in the 2 groups were compared,P>0.05.After treatment,the TCM syndrome score(frequency of urination,pain of urination,dysuria,lumbar acid,limb retrocoldness,etc.),TNF-αlevel,CD4^(+),CD8^(+),QLQ-BLM30 score and other indicators were improved in all groups.The observation group was better than the controlled group after treatment in TCM syndrome score(frequency of urination,pain of urination,dysuria,lumbar acid,limb cold,etc.),TNF-αlevel,CD4^(+),CD8^(+),QLQ-BLM30 score,P<0.05.One year later,the follow-up showed that the recurrence rate of the observation group(0.00%)was lower than that of the controlled group(8.16%),P<0.05.Conclusi

关 键 词：膀胱癌 经尿道电切术 灌注 消癥肾气汤 中医埋针 中医证候积分 

分 类 号：R737.14[医药卫生—肿瘤]