抗抑郁焦虑治疗改善脑卒中患者运动功能障碍及其机制的研究进展  

Progress in antidepressant and anxiety treatment to improve motor function and its mechanism in post-stroke patients

作　　者：郑煊璐 司马旦旦 桂丽卿 袁奕珂 SCHRODER Joana 潘卫东[1] ZHENG Xuanlu;SIMA Dandan;GUI Liqin;YUAN Yike;SCHR?DER Joana;PAN Weidong(Department of Neurology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海中医药大学附属曙光医院神经内科,上海201203

出　　处：《神经病学与神经康复学杂志》2019年第4期156-161,共6页Journal of Neurology and Neurorehabilitation

摘　　要：随着对脑卒中后肢体运动功能改善的研究不断深入,越来越多的文献报道抗抑郁焦虑药不仅能够改善脑卒中后的抑郁焦虑症状,还能够促进脑卒中后肢体运动功能的恢复。近年来,国内外研究对抗抑郁焦虑的中西医药物是否具有改善脑卒中患者肢体运动功能障碍的作用及其机制进行了探讨。本文对脑卒中后抗抑郁焦虑的中西医药物改善或独立改善脑卒中患者肢体运动功能障碍的作用及其机制的最新进展进行综述,旨在为脑卒中后肢体运动功能障碍的预防、治疗和康复提供参考。With in-depth research on motor function recovery after stroke,more and more literatures have reported that antidepressant and anxiety treatment is not only effective for post-stroke depression and anxiety,but also significantly promotes the recovery of motor function after stroke.In recent years,it has been studied whether the traditional Chinese and Western medicine drugs against depression and anxiety can improve the recovery of motor function in post-stroke patients,and its mechanism has been discussed.In this paper,the latest progress in the role and mechanism of Chinese and Western medicine in improving or independently improving the limb motor function in post-stroke patients is reviewed,in order to provide references for the prevention,treatment and rehabilitation of limb motor dysfunction after stroke.

关 键 词：卒中 运动功能障碍 抑郁 焦虑 选择性5-羟色胺再摄取抑制药 选择性去甲肾上腺素再摄取抑制药 中成药 药物作用机制 

分 类 号：R743.3[医药卫生—神经病学与精神病学]