益气化痰通络方联合针刺治疗气虚痰阻型脑梗死恢复期临床研究  

Clinical Study on Yiqi Huatan Tongluo Prescription Combined with Acupuncture for Cerebral Infarction of Qi Deficiency and Phlegm Obstruction Type in Convalescence

作　　者：毛萍 王长德 MAO Ping;WANG Changde(Department of Encephalopathy,Shanghai TCM-Integrated Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200080,China)

机构地区：[1]上海中医药大学附属上海市中西医结合医院脑病科,上海200080

出　　处：《新中医》2023年第20期57-62,共6页New Chinese Medicine

基　　金：上海市虹口区“国医强优”三年行动计划项目(HGY-YSZK-2018-10)

摘　　要：目的:观察益气化痰通络方联合针刺治疗气虚痰阻型脑梗死恢复期患者的临床疗效、安全性及对血清铁蛋白水平的影响。方法:选取气虚痰阻型脑梗死恢复期患者114例,采用随机数字表法将患者分为2组各57例,对照组给予西药基础治疗及康复治疗,治疗组在此基础上给予益气化痰通络方联合针刺治疗,疗程为21 d。比较治疗前后2组美国国立卫生研究院卒中量表(NIHSS)评分、日常生活活动能力(ADL)评分、中医临床证候评分、血清铁蛋白(SF)水平变化情况及不良事件情况。结果:临床疗效总有效率治疗组77.36%,明显高于对照组54.55%,差异有统计学意义(P<0.05);2组NIHSS评分均较治疗前降低,且治疗组NIHSS评分低于对照组,差异均有统计学意义(P<0.05);2组ADL评分均较治疗前升高,且治疗组ADL评分高于对照组,差异均有统计学意义(P<0.05);2组中医临床证候评分均较治疗前降低,且治疗组中医临床证候评分低于对照组,差异均有统计学意义(P<0.05);2组血清SF水平均较治疗前降低,且治疗组SF水平低于对照组,差异均有统计学意义(P<0.05)。治疗期间,2组血常规、尿常规、肝肾功能、凝血功能未见明显异常。结论:益气化痰通络方联合针刺治疗能改善气虚痰阻型脑梗死恢复期患者的神经功能缺损程度、日常生活活动能力、中医临床证候,降低患者SF水平,无明显不良反应。Objective:To observe the clinical effects,safety of Yiqi Huatan Tongluo Prescription combined with acupuncture for patients with cerebral infarction of qi deficiency and phlegm obstruction type in convalescence and its effect on ferritin levels in serum.Methods:A total of 114 patients with cerebral infarction of qi deficiency and phlegm obstruction type in convalescence were selected and randomly divided into two groups with 57 cases in each group.The control group received basic western medicine treatment and rehabilitation treatment,and the treatment group received Yiqi Huatan Tongluo Prescription combined with acupuncture.Both groups were treated for 21 days.The changes in scores of NIHSS,activities of daily living(ADL),traditional Chinese medicine(TCM)syndrome scores,serum ferritin(SF)levels and adverse events in the two groups were compared between the two groups before and after treatment.Results:The total clinical effective rate was 77.36%in the treatment group,significantly higher than that of 54.55%in the control group,the difference being significant(P<0.05);the NIHSS scores in the two groups were decreased when compared with those before treatment,and the NIHSS score in the treatment group was lower than that in the control group,differences being significant(P<0.05).The ADL scores in the two groups were increased when compared with those before treatment,and the ADL score in the treatment group was higher than that in the control group,differences being significant(P<0.05).The TCM syndrome scores in the two groups were decreased when compared with those before treatment,and the TCM syndrome score in the treatment group was lower than that in the control group,differences being significant(P<0.05).The levels of SF in the two groups were lower than those before treatment,and the SF level in the treatment group was lower than that in the control group,differences being significant(P<0.05).During the treatment period,there were no significant abnormalities in blood routine,urine routine,liver and kidney f

关 键 词：脑梗死 缺血性脑卒中 气虚痰阻 益气化痰通络方 针刺 

分 类 号：R743.3[医药卫生—神经病学与精神病学]