清肺化痰、通腑泻热法治疗脑卒中术后肺部感染痰热腑实证临床研究  

Clinical Study on Method of Clearing Lung Heat and Resolving Phlegm,and Unblocking the Bowels and Discharging Heat for Pulmonary Infection with Phlegm-Heat and Bowel Excess Syndrome After Operation for Stroke

作　　者：王松鹤 周笑非 张亚丽 孟凡学 司建伟 金晓烨 赵新爱 WANG Songhe;ZHOU Xiaofei;ZHANG Yali;MENG Fanxue;SI Jianwei;JIN Xiaoye;ZHAO Xin'ai(Kaifeng People's Hospital,Kaifeng Henan 475000,China)

机构地区：[1]开封市人民医院,河南开封475000

出　　处：《新中医》2023年第13期62-66,共5页New Chinese Medicine

摘　　要：目的:观察清肺化痰、通腑泻热法治疗脑卒中术后肺部感染痰热腑实证的临床疗效。方法:选取86例脑卒中术后并发肺部感染痰热腑实证的患者作为研究对象,采用随机数字表法分为观察组与对照组各43例。对照组给予常规西医治疗,观察组在对照组的基础上给予清肺化痰、通腑泻热法中药治疗。比较2组治疗前后肺功能指标、临床肺部感染评分(CPIS)、炎症因子[血清C-反应蛋白(CRP)、白细胞介素6(IL-6)、降钙素原(PCT)]水平,并比较2组临床症状体征消失时间及临床疗效。结果:治疗前,2组用力肺活量(FCV)、每分钟最大通气量(MVV)、呼气最高峰流速(PEF)比较,差异无统计学意义(P>0.05);治疗后,2组FCV、MVV、PEF水平均升高(P<0.05),且观察组高于对照组(P<0.05)。观察组患者发热、咳嗽、咳痰及肺部湿啰音消失时间均短于对照组(P<0.05)。治疗前,2组CPIS评分和CRP、IL-6、PCT水平比较,差异无统计学意义(P>0.05);治疗后,2组CPIS评分和CRP、IL-6、PCT水平均降低(P<0.05),且观察组低于对照组(P<0.05)。观察组治疗总有效率95.35%,高于对照组79.07%(P<0.05)。结论:清肺化痰、通腑泻热法治疗脑卒中术后肺部感染痰热腑实证患者疗效确切,可有效缓解患者的临床症状,改善肺功能指标,减轻肺部感染,降低炎症因子水平。Objective:To observe the clinical effect of the method of clearing lung-heat and resolving phlegm,and unblocking the bowels and discharging heat for pulmonary infection with phlegm heat and bowel excess syndrome after operation for stroke.Methods:A total of 86 cases of patients with pulmonary infection with phlegm-heat and bowel excess syndrome after operation for stroke were selected as the study objects,and were divided into the observation group and the control group according to the random number table method,with 43 cases in each group.The control group was given routine western medicine treatment,and the observation group was additionally treated with Chinese medicine with the method of clearing lung-heat and resolving phlegm,and unblocking the bowels and discharging heat based on the treatment of the control group.Before and after treatment,the lung function indexes,the Clinical Pulmonary Infection Scores(CPIS),and the levels of inflammatory factors[C-reactive protein(CRP),interleukin 6(IL-6),and procalcitonin(PCT)in serum]were compared between the two groups.The disappearance time of clinical symptoms and the clinical effects were compared between the two groups.Results:Before treatment,there was no significant difference being found in the comparison of forced vital capacity(FCV),maximal voluntary ventilation(MVV)per minute,and peak expiratory flow rate(PEF)between the two groups(P>0.05).After treatment,the levels of FCV,MVV,and PEF in the two groups were increased(P<0.05),and the above levels in the observation group were higher than those in the control group(P<0.05).The disappearance time of fever,cough,sputum and pulmonary moist rales in the observation group was shorter than that in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of CPIS scores,and the levels of CRP,IL-6,and PCT between the two groups(P>0.05).After treatment,CPIS scores,and the levels of CRP,IL-6,and PCT in the two groups were decreased(P<0.05),and the above indexes in the

关 键 词：脑卒中术后 肺部感染 清肺化痰、通腑泻热法 痰热腑实证 肺功能指标 炎症因子 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R563.1[医药卫生—临床医学]