常规超声和超声造影检查不同大小病灶乳腺癌的比较研究  

A comparative study on breast cancer between smaller and larger diameters using conventional ultrasound and contrast-enhanced ultrasound

作　　者：刘淼[1,2] 沈燕[2] 傅晓红[2] 胡姣姣[2] 陈庆庆 应涛 LIU Miao;SHEN Yan;FU Xiaohong;HU Jiaojiao;CHEN Qingqing;YING Tao(Suzhou Medical College of Soochow University,Jiangsu Suzhou 215123,China;Department of Ultrasound,Gongli Hospital of Pudong New District,Shanghai 200135,China;Department of Ultrasound,Sixth People′s Hospital,Shanghai 200233,China)

机构地区：[1]苏州大学苏州医学院,江苏苏州215123 [2]上海市浦东新区公利医院超声医学科,上海200135 [3]上海市第六人民医院超声医学科,上海200233

出　　处：《外科理论与实践》2022年第3期229-233,共5页Journal of Surgery Concepts & Practice

摘　　要：目的:研究不同大小病灶乳腺癌常规超声及超声造影检查的特征。方法:回顾性分析107例病理诊断为乳腺癌的病人。根据肿块最大直径分为两组:≤2.0 cm组(50.5%,54/107)和>2.0 cm组(49.5%,53/107)。比较两组的常规超声检查结果与超声造影检查图像特征。结果:与>2.0 cm组比较,常规超声检查乳腺癌≤2.0 cm组易出现肿块方位不平行[19例(35.2%)比6例(11.3%),P=0.004],血流Alder分级多为0~Ⅰ级[41例(75.9%)比25例(47.2%),P=0.002]。两组差异有统计学意义。两组乳腺癌超声造影检查有4方面的特点。(1)≤2.0 cm组低增强或等增强多于>2.0cm组,[23例(42.6%)比5例(9.4%),P<0.001]。(2)肿块周围多无穿支血管[34例(63.0%)比20例(37.7%),P=0.009]。(3)肿块内多无充盈缺损[49例(90.7%)比30例(56.6%),P<0.001]。(4)造影剂廓清时间多为快出与等出[48例(88.9%)比37例(69.8%),P=0.038]。两组这些差异均有统计学意义。结论:不同大小病灶乳腺癌常规超声及超声造影检查特征不同。乳腺肿块的超声造影结果分析也要考虑病灶大小。Objective To investigate the features of breast cancer with different sizes of tumor examined using conventional ultrasound and contrast-enhanced ultrasound(CEUS).Methods A total of 107 cases with breast cancer diagnosed by pathology were retrospectively analyzed.There were one group(group≤2.0 cm)with tumor maximum diameter≤2.0 cm(50.5%,54 cases)and other group(group>2.0 cm)with that>2.0 cm(49.5%,53 cases)based on diameter of breast cancer.The features shown with both conventional ultrasound and CEUS examination were compared between two groups.Results Non-parallel orientation was more present in group≤2.0 cm than in group>2.0 cm by conventional ultrasound[19 cases(35.2%)vs.6 cases(11.3%),P=0.004].More cases with Alder grade of blood flow 0-Ⅰwere found in group≤2.0 cm than those in group>2.0 cm[41(75.9%)cases vs.25(47.2%)cases,P=0.002].There were four characteristics with differences between two groups in CEUS examination.First was there were 23(42.6%)cases of breast cancer with hypo-enhancement and iso-enhancement in≤2.0 cm group and 5(9.4%)cases in group>2.0 cm with statistically significant differences,P<0.001.Second,more cases without perforating vessels around tumor were in group≤2.0 cm than those in group>2.0 cm[34(63.0%)cases vs.20(37.7%)cases,P=0.009].Third,the cases with filling defect of contrast in tumor were more in group≤2.0 cm than in group>2.0 cm[49(90.7%)cases vs.30(56.6%)cases,P<0.001].Last was more cases with clearance time early(not late)of contrast after the enhancement in group≤2.0 cm were than in group>2.0 cm[48(88.9%)cases vs.37(69.8%)cases,P=0.038].The differences between two groups were significant statistically.Conclusions The results in this study showed that the difference in the characteristics of conventional ultrasound and CEUS imaging is clear in different size of breast cancer.The size of focus should be considered in the analysis of CEUS.

关 键 词：常规超声检查 超声造影检查 乳腺肿瘤 肿瘤大小 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]