肠道菌群与儿童抽动障碍的相关性  

Correlation between intestinal flora and tic disorder

作　　者：张盼盼 赵婷婷 肖绪武 ZHANG Panpan;ZHAO Tingting;XIAO Xuwu(Department of Child Healthcare,Dalian Municipal Women and Children′s Medical Center(Group),Dalian,Liaoning 116011,China;China Dalian Medical University)

机构地区：[1]大连市妇女儿童医疗中心(集团)儿童保健科,辽宁大连116011 [2]大连医科大学

出　　处：《中国儿童保健杂志》2024年第10期1091-1096,共6页Chinese Journal of Child Health Care

摘　　要：抽动障碍为儿童早期的慢性神经系统疾病,其发病率近年呈上升趋势,至今尚无特效的治疗手段。随着对脑-肠轴的深入研究,肠道菌群对抽动障碍的影响日益受到重视。本文在基础研究及临床试验的基础上,详述肠道菌群与抽动障碍的研究现况,并探讨肠道菌群变化在儿童抽动障碍发病中的可能作用机制及微生态制剂的潜在应用价值,旨在为抽动障碍的治疗提供一些新思路和新方法。Tic disorder(TD)is a chronic neurological disorder in early childhood.Its incidence has been on the rise in recent years,and there is no specific effective treatment.With the further study of brain-gut axis interaction,more and more attention has been paid to the influence of intestinal flora on TD.On the basis of basic research and clinical trials,this paper discusses the current situation of intestinal flora and tic disorder,discusses the possible mechanism of intestinal flora changes in the pathogenesis of TD and the potential therapeutic value of microecological agents,aiming to provide some new ideas and methods for the treatment of TD.

关 键 词：抽动障碍 肠道菌群 儿童 

分 类 号：R749.94[医药卫生—神经病学与精神病学]