Caudal and Lentiform nuclei Myelinolysis following Endoscopical surgery for pediatric Craniopharyngioma: two cases report and literature review  

作　　者：Zhi Gang Wang Lian Ying Jiang Wen Hao Zhang Tao Hong 

机构地区：[1]Department of Neurosurgery,The First Affiliated Hospital of NanChang University,No.17 YongWai Street,NanChang,JiangXi 330006,People’s Republic of China [2]Department of Neurology,Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong,China [3]Medical Image Center,Yongxin County People’s Hospital,JiAn,Jiangxi,China

出　　处：《Chinese Neurosurgical Journal》2018年第3期166-172,共7页中华神经外科杂志（英文）

基　　金：National Natrural Science Foundation of China(No.81460381);GanPo Excellence 555 Projection of Science and Technology department of JiangXi province(2013).

摘　　要：Background: The extrapontine myelinolysis (EPM) of osmotic demyelination syndrome (ODS) is a rare and dangerous disorder of the central nervous system. The mechanism is not fully understood and the treatment is controversial. There are few reports of EPM occurred after endonasal endoscopic resection of pediatric craniopharyngioma. Case presentation: We report two unusual cases of such a rare condition. Both are procedured uneventful endonasal endoscopical craniopharyngioma resection, after operation, the patients suffered serious diabetic insipidus with remarkable fluctuation of serum sodium though we applied pitutrin continual management to maintain everyday normal urine and correct serum sodium disorder. MR images occured caudal and lentiform nuclei myelinolysis following these serious conditions. Conclusions: In this study relevant literatures are reviewed in order to further understand this complication and contribute to the prevention and treatment of EPM caused by inappropriate correction of serum sodium disorder.

关 键 词：Extrapontine myelinolysis(EPM) CRANIOPHARYNGIOMA ENDONASAL endoscopic SURGERY SIADH HYPERNATREMIA 

分 类 号：R73[医药卫生—肿瘤]