Clinical research on curative effect of treatment on patients with gouty renal stone by hydration-alkalization therapy  

作　　者：Ning Mao Ying Liu 

机构地区：[1]Department of Liberation Army,Hangzhou Clinical college of Anhui Medical University,Hangzhou,310007,Zhejiang Province,China [2]Department of Endocrinology,Airport Road District of No.903 Hospital of People's Liberation Army,Hangzhou,310004,Zhejiang Province,China

出　　处：《Journal of Hainan Medical University》2019年第8期58-61,共4页海南医学院学报（英文版）

摘　　要：Objective:Study the clinical effect of intravenous hydration and alkalization therapy on uric acid nephrolithiasis.Methods: Sixty-five patients with 86 stones admitted to Department of Endocrinology and Urinary Nephropathy from December 2015 to December 2017 in our hospital were divided into control group (n= 31) and Treatment group (n = 34) with at random. Both groups were given basic treatment with low purine diet and the control group was treated with oral sodium bicarbonate tablets + oral rehydration 1000 mL / d. The treatment group was treated with hydration alkalosis treatment by 0.9% saline 500 mL + 5% sodium bicarbonate injection of 60 mL + 10% potassium chloride injection 10 mL intravenous infusion, 2 times/d. Two groups were treated for a course of treatment (10 d), respectively, detecting relevant laboratory parameters and imaging studies before and after treatment for assessing the effectiveness of treatment.Result: The total effective rate of the treatment group was 86.67%, which was significantly better than the control group (4.88%).Conclusion: It is a significant effect that Intravenous hydration alkalosis therapy for the treatment of uric acid nephrolithiasis. The diameter of less than 0.5 cm stones disappears, and the diameter of 0.5-0.8 cm stone was significantly reduced. As it can improve stone related renal insufficiency with low cost, it is widely recommended in clinical.

关 键 词：Intravenous HYDRATION ALKALOSIS Uric acid NEPHROLITHIASIS 

分 类 号：R73[医药卫生—肿瘤]