Immunologic characteristics and predictive risk factors of primary Sjögren’s syndrome complicated with malignant lymphoma:A multicenter case-control study  

作　　者：Yuebo Jin Linqing Hou Hao Li Liyun Zhang Yuanhong Peng Naidi Wang Jing He 

机构地区：[1]Department of Rheumatology and Immunology,Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis,Peking University People’s Hospital,Beijing 100044,China [2]Department of Rheumatology and Immunology,Linfen Third People’s Hospital,Linfen,Shanxi 041000,China [3]Department of Rheumatology and Immunology,Huabei Petroleum Administration Bureau General Hospital,Cangzhou,Hebei 062552,China [4]Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan 637000,China

出　　处：《Chinese Medical Journal》2024年第10期1252-1254,共3页中华医学杂志（英文版）

基　　金：National Natural Science Foundation of China and by the Beijing Sci-Tech Program(No.Z191100006619114);Natural Science Foundation of China(No.81701607);Peking University People’s Hospital Scientific Research Development Funds(No.RDZH2022-03)

摘　　要：To the Editor:Primary Sjögren’s syndrome(pSS)is a multi-systemic autoimmune disease characterized by the exocrine gland(mainly salivary and lacrimal glands)involvement,leading to xerostomia and xerophthalmia.[1]The course of pSS is relatively slow,but patients with pSS had higher risk of overall cancer,including malignant lymphoma(ML).[2]It is widely known that all-cause mortality rates were not increased in pSS patients as compared with healthy controls.Nonetheless,secondary lymphoproliferative disease was an important cause of excess mortality.

关 键 词：mortality LYMPHOMA MALIGNANT 

分 类 号：R733.1[医药卫生—肿瘤]