Downregulation of microRNA-23a confers protection against myocardial ischemia/reperfusion injury by upregulating tissue factor pathway inhibitor 2 following luteolin pretreatment in rats  

作　　者：Yuanyuan Luo Li Li Lele Wang Pingping Shang Defeng Pan Yang Liu Tongda Xu Dongye Li 

机构地区：[1]Department of Cardiology,The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221006,China [2]Institute of Cardiovascular Disease Research,Xuzhou Medical University,Xuzhou,Jiangsu 221002,China

出　　处：《Chinese Medical Journal》2023年第7期866-867,共2页中华医学杂志（英文版）

基　　金：National Natural Science Foundation of China(No.81570326);Natural Science Foundation of Jiangsu Province(Nos.BK20141139,BK20190988);Jiangsu Commission of Health Foundation(No.H2018005);Key Research and Development program of Xuzhou(No.KC20097)

摘　　要：To the Editor:Myocardial ischemia/reperfusion injury(MI/RI)often causes death,dysfunction,or damage to the cardiomyocytes,and thus more effective clinical treatments are required.[1]MicroRNAs(miRNAs)bind to target mRNAs to regulate post-transcriptional gene expression,with important effects on MI/RI by regulating critical molecular signaling pathways.

关 键 词：INJURY clinical MYOCARDIAL 

分 类 号：R285[医药卫生—中药学]