儿童膀胱/前列腺横纹肌肉瘤治疗进展  

Recent advances in the treatment of bladder/prostate rhabdomyosarcoma in children

作　　者：杨屹[1] 刘鑫[1] Yang Yi;Liu Xin(Department of Pediatric Urology,Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院小儿泌尿外科,沈阳110004

出　　处：《临床小儿外科杂志》2022年第12期1101-1105,共5页Journal of Clinical Pediatric Surgery

摘　　要：横纹肌肉瘤是儿童和青年最常见的软组织肉瘤,其中膀胱/前列腺横纹肌肉瘤约占5%。经国际肿瘤协作组多年临床研究,不断更新治疗方案以及多学科协作综合治疗,儿童横纹肌肉瘤的整体存活率有所提高。然而,高风险横纹肌肉瘤的治疗进展缓慢。另外,在提高患儿存活率的前提下,如何减少近、远期并发症,提高患儿生活质量是临床急需解决的问题。由于国内各地区医疗水平的差异,我国儿童横纹肌肉瘤的总体存活率较国际水平仍然存在差距,为了提高小儿泌尿外科专业医师对该疾病的认识,本文就儿童膀胱/前列腺横纹肌肉瘤的治疗进展进行阐述。Rhabdomyosarcoma(RMS)is the most common soft tissue sarcoma in children and young adults,with bladder/prostate rhabdomyosarcoma being identified in 5%of cases.The overall survival for children with RMS has improved over the last five decades with multi-modal treatment.However,little progress has been made in the treatment of high-risk group children,whose outcomes remain poor despite aggressive multimodal treatment.In addition,as more patients survive longer,how to improve the quality of life of children and reduce short-term and long-term complications are also clinical challenge to be faced.Due to the different levels of medical treatment in various regions,the overall survival rate of children with rhabdomyosarcoma in China is still different from the international standard.In order to improve the recognition of pediatric urologists on the disease,this article describes the progress in the treatment of bladder/prostate rhabdomyosarcoma in children.

关 键 词：横纹肌肉瘤 放射疗法 药物疗法 泌尿生殖外科手术 病理学 外科 儿童 

分 类 号：R73[医药卫生—肿瘤]