永存胚胎血管的研究进展  

Advance on the persistent fetal vasculature

作　　者：赵超 郑超 周健 Zhao Chao;Zheng Chao;Zhou Jian(Department of Ophthalmology,Eye Institute of People′s Liberation Army,Xijing Hospital,Air Force Medical University,Xi′an 710032,China)

机构地区：[1]空军军医大学西京医院眼科全军眼科研究所,西安710032

出　　处：《中华眼科医学杂志（电子版）》2022年第6期352-356,共5页Chinese Journal of Ophthalmologic Medicine(Electronic Edition)

基　　金：陕西省自然科学基础研究计划项目(2019JM-065)

摘　　要：永存胚胎血管(PFV)是一组因眼部胚胎血管异常退化而导致的疾病,分为前部型、后部型及混合型。PFV呈散发性,95%为单眼发病,临床表现多样,并发症多且复杂,易与多种婴幼儿常患眼部疾病混淆,临床诊断难度大。目前,尚无PFV权威的指南颁布,且其在手术切口选择、后极部病变的治疗方式上尚存争议。加之,当前临床医师对PFV的认识并不充分,漏诊和误诊率高,整体预后水平差。因此,本文中笔者就PFV胚胎起源、病因、临床表现、诊断、鉴别诊断、治疗及预后的研究进展进行综述。Persistent fetal vasculature(PFV)is a spectrum of disorders resulted from abnormal regression of ocular fetal vessels,which is classified into three types of anterior,posterior as well as combined.PFV presents sporadic with 95%of which is unilateral.The clinical manifestations of PFV are diverse with so many perplexed complications and is easily confused with other common eye diseases in infants and young children,made clinical diagnosis more difficult.There are no authoritative guidelines to guide treatment of PFV,and controversies exist in the treatment attitude of posterior pole lesions and the selection of surgical incisions.Moreover,clinicians do not know enough about PFV,resulting in a high rate of missed diagnosis and misdiagnosis,and the overall prognosis is poor.Therefore,the relevant literature on its embryonic origin and etiology,clinical manifestations,diagnosis and differential diagnosis,treatment,prognosis and basic research progress were reviewed.

关 键 词：永存胚胎血管 永存原始玻璃体增生症 玻璃体血管 手术治疗 

分 类 号：R73[医药卫生—肿瘤]