Analysis and Comparison of Adverse Reactions of Erythromycin and Azithromycin  

红霉素阿奇霉素药物不良反应分析比较

作　　者：SONG Lin 

机构地区：[1]Xixia People's Hospital, Nanyang He’nan 474500, China

出　　处：《外文科技期刊数据库(文摘版)医药卫生》2021年第12期1076-1079,共6页

摘　　要：Objective: to study the adverse reactions of roxithromycin and azithromycin. Methods: among the patients investigated in our hospital, 200 cases were selected for the study. In terms of drug use, roxithromycin and azithromycin were respectively used in the two groups. Patients were selected in April 2019 and April 2020 to observe the adverse reactions. Results: the overall adverse reactions of azithromycin and roxithromycin were analyzed in 200 patients. Adverse reactions occurred in 10 patients after intravenous administration, compared with 6 patients after oral administration. Adverse reactions included nervous system, digestive system and gastrointestinal tract reactions. Digestive system reaction was the majority of adverse reactions, with a total of 7 cases and an incidence of 43.75%. In addition, all patients had more adverse reactions within 30 minutes of drug use. There were 11 persons, accounting for 68.75% of the total population. After a few days of drug use, the adverse reactions gradually decreased. After the adverse reactions occurred in the patients, 4 patients stopped taking drugs, 6 patients cooperated with antiallergic drugs, and 6 patients cooperated with antipyretic drugs. In terms of drug types, gastrointestinal reactions were more common in patients treated with azithromycin. Conclusion: in clinical practice, the incidence of adverse reactions of roxithromycin and azithromycin is not high, but according to the different types of drugs, different ways will lead to adverse reactions in patients, therefore, it is necessary to supervise the use method and dose of roxithromycin and azithromycin, to rational drug use.

关 键 词：ROXITHROMYCIN AZITHROMYCIN adverse reactions rational application COMPARE 

分 类 号：R978.1[医药卫生—药品]