云南高校图书馆联盟文献共享服务平台- ROXITHROMYCIN

ROXITHROMYCIN: 作品数：12被引量：20H指数：3; 导出分析报告; 相关作者：钟大放张淑秋黄海华毛安华陈汉源更多>>; 相关机构：沈阳药科大学沈阳药学院上海医科大学附属华山医院北京理工大学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《外文科技期刊数据库（文摘版）医药卫生》《化工学报》《China Medical Abstracts(Internal Medicine)》更多>>; 相关基金：国家自然科学基金王宽诚敎育基金国家科技支撑计划更多>>

Analysis and Comparison of Adverse Reactions of Erythromycin and Azithromycin: 《外文科技期刊数据库(文摘版)医药卫生》2021年第12期1076-1079,共6页SONG Lin; Objective: to study the adverse reactions of roxithromycin and azithromycin. Methods: among the patients investigated in our hospital, 200 cases were selected for the study. In terms of drug use, roxithromycin and azi...; 关键词：ROXITHROMYCIN AZITHROMYCIN adverse reactions rational application COMPARE

Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells被引量：3: 《Acta Pharmacologica Sinica》2021年第12期2058-2068,共11页Xuan Zhang Ying Dong Wan-chen Li Bi-xi Tang Jia Li Yi Zang; supported by the National Science and Technology Major Project"Key New Drug Creation and Manufacturing Program"(2019ZX09201001-004-010,2019ZX09201001-003-010);the National Natural Science Foundation of China(Grant U1703235,31871414);the National Science Fund for Distinguished Young Scholars(Grant 81125023);the K.C.Wong Education Foundation.; Idiopathic pulmonary fibrosis(IPF)is an aging-associated disease with a poor prognosis.Emerging evidence has revealed that targeting senescent cells may be a potential treatment for IPF.In this study,we aimed to explo...; 关键词：idiopathic pulmonary fibrosis cellular senescence ROXITHROMYCIN NOX4 senescence-associated secretory phenotype(SASP)

Cytochrome P450 monooxygenase specific activity reduction in wheat Triticum aestivum induced by soil roxithromycin stress被引量：1: 《Frontiers of Environmental Science & Engineering》2016年第2期270-275,共6页Kangxin HE Qixing ZHOU; This research is financially supported by the National Natural Science Foundation of China as a general project （Grant No. 31170473） and a joint Guangdong project （No. U1133006）, and by the Ministry of Education of China as an innovative team project （No. IRT 13024）.; Roxithromycin, livestock growth promoter, as widely used medicine and arouses concern because its occurrence and persistence in soil environments. However, effects of roxithromycin in higher plants are still vague. Ac...; 关键词：ROXITHROMYCIN toxic effect cytochrome P450monooxygenase soil environment Triticum aestivum biomarker

Impact of treatment with low dose roxithromycin on stable bronchiectasis: 《China Medical Abstracts(Internal Medicine)》2013年第1期39-39,共1页刘积锋; Objective To investigate the impact of treatment with low dose roxithromycin on clinical symptoms and CT scores in patients with stable bronchiectasis. Methods Fifty patients with bronchiectasis in stable condition we...; 关键词：BRONCHIAL assigned TABLET questionnaire THORAX assessed disperse alone

Metabolism of roxithromycin in phenobarbital-treated rat liver microsomes: 《Acta Pharmacologica Sinica》2002年第5期73-78,共6页钟大放张淑秋孙璐赵晓云; Project supported by the National Naturul Science Foundation of China. № 39930180.; AIM: To investigate the metabolism of roxithromycin (RXM) in rat liver microsomes and the possible effects of RXM and its metabolites on cytochrome P-450 (CYP450). METHODS: Liver microsomes of Wistar rats, induced by ...; 关键词：ROXITHROMYCIN METABOLISM micro- somes cytochrome P-150 mass spectrum analysis

Determination of Roxithromycin Tablets by Capillary Electrophoresis Employing Non-aqueous Media with Square-wave Amperometric Detection: 《Chinese Chemical Letters》2002年第5期440-441,共2页Na LI Tian Yao XIE Jin Yuan MO; This work was supported by the National Natural Science Foundation of China and Guang Dong Provincial Natural Science Foundation(29675033 and 20175037; 001237); A new method of determination for roxithromycin tablets by non-aqueous capillary electrophoresis (NACE) with square-wave amperometric detection was carried out. Several parameters affecting the NACE-AD determination ...; 关键词：Non-aqueous capillary electrophoresis (NACE) amperometric detection ROXITHROMYCIN spline wavelet least square (SWLS).

Demethylation metabolism of roxithromycin in humans and rats: 《Acta Pharmacologica Sinica》2001年第5期89-94,共6页李雪庆钟大放黄海华吴硕东; Project supported by the National Natural Science Foundation of China, No 39625025 and 39930180; AIM: To investigate the demethylated metabolites of roxithromycin (RXM) in humans and rats, and to study the antibiotic activity of these metabolites in vitro. METHODS: The demethylated metabolites of RXM in humans an...; 关键词：ROXITHROMYCIN METABOLISM macrolide antibiotics liquid chromatography mass spectrum analy-sis

Roxithromycin的药效学研究被引量：2: 《中国抗生素杂志》1995年第4期284-287,共4页李华林朱国强张蕾钟惠君; 报道国产ｒｏｘｉｔｈｒｏｍｙｃｉｎ（ＲＯＸ）对２０５株临床致病菌体内外抗菌活性及不同试验条件对抗菌活性的影响，并与进口产品及红霉素、麦迪霉素、柱晶白霉素、青霉素钾盐的抗菌活性进行比较。还进行了杀菌试验，结果表明，国产...; 关键词：ROXITHROMYCIN 抗菌活性大环内酯抗生素

两种新型的红霉素衍生物Clarithromycin和Roxithromycin被引量：9: 《沈阳药学院学报》1994年第3期228-234,共7页黄海华; 两种新型的红霉素衍生物Ｃｌａｒｉｔｈｒｏｍｙｃｉｎ和Ｒｏｘｉｔｈｒｏｍｙｃｉｎ黄海华沈阳药学院制药系１１００１５自４０年前发现红霉素（Ｅｒｙｔｈｒｏｍｙｃｉｎ）以来，针对这类天然抗菌物质的关键性弱点（体内消除半衰期短...; 关键词：红霉素衍生物化学结构

抗生素罗希红霉素(Roxithromycin): 《国外医药（合成药．生化药．制剂分册）》1991年第5期303-304,共2页雷招宝; 化学名红霉素9-[O-(2-甲氧基乙氧基)-甲基]-肟药效分类口服大环内酯类抗生素开发单位 (法)罗塞尔·尤克拉夫公司上市厂商 (法)罗塞尔·尤克拉夫公司1988年首次上市药理与红霉素相同,本品也是通过抑制细菌细胞蛋白质合成而发挥抑菌作用...; 关键词：抗生素红霉素药动学适应症

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