Study on Local Application of Dexamethasone Palmitate Injection in Treatment of Hoarseness Caused by Recurrent Laryngeal Nerve Injury During Thyroid Surgery  

作　　者：CHENYuan CAOShiyan LIBiao 

机构地区：[1]Guizhou Provincial People's Hospital, Guiyang 550002, China

出　　处：《外文科技期刊数据库(文摘版)医药卫生》2022年第6期208-212,共5页

摘　　要：Objective: to observe the therapeutic effect of dexamethasone palmitate injection on hoarseness caused by recurrent laryngeal nerve injury during thyroid surgery. Methods: 783 patients were divided into treatment group (395 cases) and control group (388 cases). After thyroidectomy, the treatment group was sprayed with dexamethasone palmitate injection 1ml:4mg, while the control group was not sprayed with any drugs. The patients' hoarseness was observed on the 1st, 3rd, 7th and 30th day after operation. The GRBAS score, voice disorder index and VHI-13 Chinese version scale were used to evaluate the patients' voice. At the same time, the occurrence of severe adverse drug reactions, upper abdominal pain and hyperglycemia within 7 days after operation, and the infection in the operation area within 30 days after operation were observed. Results: the hoarseness in the treatment group was less than that in the control group on the 1st, 3rd and 7th day after operation (p<0.05), and there was no significant difference between the two groups on the 30th day after operation (p>0.05). There was no serious adverse drug reaction in the treatment group, upper abdominal pain and hyperglycemia within 7 days after operation, and there was no significant difference between the two groups within 30 days after operation (p>0.05). Conclusion: local application of dexamethasone palmitate injection during thyroid surgery has a certain therapeutic effect on reducing hoarseness caused by recurrent laryngeal nerve injury, but it has a limited therapeutic effect on recurrent laryngeal nerve injury which has not recovered its voice 30 days after operation.

关 键 词：dexamethasone palmitate thyroid surgery recurrent laryngeal nerve HOARSENESS 

分 类 号：R[医药卫生]