Alteration of Crystallin Polypeptides in Rat Lenses during the Development of Galactose-induced Cataract  

作　　者：Huiren Zhao Xiaoheng Ren Department of Biochemistry,Xuzhou Medical College Xuzhou 221002,China 

出　　处：《眼科学报》1993年第3期143-145,共3页Eye Science

摘　　要：Some striking differences in relative polypeptide abundanceof crystallins were observed in normal and galactose-induced cataractouslenses of rat by means of SDS-PAGE.In the cataractous lenses aprominent band appeared at about 25 kDa and the αA chain increasedmarkedly,whereas the relative amount of the 31 kDa band decreasedsubstantially.These alterations are similar to the changes observed duringthe incubation of young mouse lenses in glucose-free medium.Eye Science1993;9:143-145.Some striking differences in relative polypeptide abundance of crystallins were observed in normal and galactose-induced cataractous lenses of rat by means of SDS-PAGE.In the cataractous lenses a prominent band appeared at about 25 kDa and the αA chain increased markedly,whereas the relative amount of the 31 kDa band decreased substantially.These alterations are similar to the changes observed during the incubation of young mouse lenses in glucose-free medium.Eye Science 1993;9:143-145.

关 键 词：rat lens galactose cataract crystallin polypeptide 

分 类 号：R77[医药卫生—眼科]