Synthesis of Chiral Sulfoxides and Application in Enantioselective Allylation of Aldehydes with Allyltrichlorosilane  

作　　者：A.Massa V.De Sio R.Villano A.Scettri 

机构地区：[1]Department of Chemistry,University of Salerno

出　　处：《复旦学报（自然科学版）》2007年第5期571-,共1页Journal of Fudan University：Natural Science

摘　　要：1 Results The enantioselective addition of allylic organometallic reagents to aldehydes is a fundamental tool in organic synthesis.The high degree of both diastereo-and enantioselectivity gives the possibility to obtain a wide series of homoallylic alcohols,versatile intermediates in a great number of synthesis[1]. One of the most successful approaches is related to the discovery that organocatalytic activation of the nucleophilic allyltrichlorosilanes by means of neutral Lewis bases,such as formamides,...

关 键 词：SULFOXIDES lewis bases ORGANOCATALYSIS allylation reaction 

分 类 号：O621.2[理学—有机化学]