高危高龄肺癌患者120例单纯外科治疗临床研究  

Surgical treatment of 120 high risk elderly patients with lung cancer

作　　者：张春芳[1] 张恒[1] 郭海周[1] 陈胜喜[1] 

机构地区：[1]中南大学湘雅医院胸外科,长沙410008

出　　处：《中国肺癌杂志》2007年第4期306-309,共4页Chinese Journal of Lung Cancer

摘　　要：背景与目的老年人是肺癌的高发群体,其特殊的身体状况使得对肺癌的治疗更加困难。本研究的目的是探讨高龄高危肺癌患者的最佳外科治疗手段及围手术期处理方式。方法回顾高龄高危肺癌患者120例,随访5年后总结临床资料。结果无术中死亡,术后呼吸衰竭死亡4例,心肌梗死死亡2例,围手术期死亡率为5.0%。全组1年生存率为67.7%,3年生存率为41.7%,5年生存率为28.1%。结论各种相关疾病的及时处理是降低围手术期死亡率的关键,也在一定程度上影响患者术后的生活质量。"最大限度地根治疾病"对高龄患者而言并不一定是最好的选择。肺叶切除术+阳性淋巴结的清扫以及肺段切除术可能是此类患者的最佳手术方式。Background and objective Lung cancer is easy to occur in patients older than 70 years, whose special health condition makes their treatment more difficult. The aim of this study is to investigate the best surgical treatment and perioperative management for high risk elderly patients with lung cancer. Methods After 5 years’ follow-up, 120 high risk elderly patients with lung cancer were analyzed retrospectively. Results Of 120 patients, there was no operative death. Four patients died of respiration failure and 2 died of myocardial infarction. Perioperational death rate was 5.0%. The overall 1-, 3-and 5-year survival rate was 67.7%, 41.7% and 28.1%, respectively. Conclusion Appropriate management of complications is the key point to decrease perioperative death rate, and it may influence the quality of life of patients. To resect tumor maximally may be not the best choice for elderly patients. Lobectomy or segmental resection combined with positive lymph node dissection may be the considerable patterns.

关 键 词：老年人 伴随疾病 肺肿瘤 外科学 围手术期 

分 类 号：R734.2[医药卫生—肿瘤]