15例肺恶性纤维组织细胞瘤临床分析  

Clinical analysis of 15 patients with pulmonary malignant fibrous histiocytoma

作　　者：蒋雷[1] 陈晓峰[1] 易祥华[2] 郑卉[2] 姜格宁[1] 张鹏[1] 刘业六[1] 丁嘉安[1] 

机构地区：[1]同济大学附属上海市肺科医院胸外科,200433 [2]同济大学附属上海市肺科医院病理科,200433

出　　处：《中国肺癌杂志》2007年第4期313-315,共3页Chinese Journal of Lung Cancer

摘　　要：背景与目的 肺恶性纤维组织细胞瘤(MFH)十分罕见.本研究旨在探讨肺MFH的临床特点、治疗方法及预后.方法 回顾性分析经手术病理证实的15例肺原发性MFH.结果 本组男性10例,女性5例;年龄56.2岁±14.0岁(20～72岁).主要症状:咳嗽、咯血、发热、胸痛、气急.肿瘤直径8.3 cm±8.0 cm,最大35 cm,最小0.3 cm.以手术治疗为主,全肺切除术5例、肺叶切除术8例、剖胸探查术2例.1年、3年、5年生存率分别为56.2%、24.1%、16.7%.姑息性手术患者预后差.结论 肺原发性MFH恶性度高,预后差,外科手术是主要治疗手段.Background and objective Pulmonary malignant fibrous histiocytoma (MFH) is very rare and it is worthy to study the clinical characteristics, treatment method and prognosis of primary pulmonary MFH. Methods Fifteen patients with primary pulmonary MFH were reviewed retrospectively. Results There were 10 males and 5 females. Their ages were 56.2 years±14.0 years (20-72 years). MFH mainly manifested as cough, hemoptysis, fever, chest pain and breathlessness. The diameters of tumors were 8.3 cm±8.0 cm, ranged from 0.3 to 35 cm. All the patients received surgical operations, including 5 pneumonect-omy, 8 lobectomy and 2 exploration. The overall 1-, 3-and 5-year survival rate of 15 patients was 56.2%, 24.1% and 16.7% respectively. Incomplete surgical excision of tumor significantly influenced survival. Conclusion Pulmonary MFH is a high-grade malignant tumor with poor prognosis, and surgery is the main treatment method.

关 键 词：肺切除术 恶性纤维组织细胞瘤 预后 

分 类 号：R734.2[医药卫生—肿瘤]