液相色谱-串联质谱鉴别7种糖皮质激素的方法研究  

Studies on Identification of Seven Glucocorticoids by HPLC-MS/MS

作　　者：张雅军[1] 李晓东[1] 

机构地区：[1]中国药品生物制品检定所,北京100050

出　　处：《分析测试学报》2007年第z1期67-68,共2页Journal of Instrumental Analysis

摘　　要：To develop a HPLC ion trap tandem MS method for quantitative analysis of seven glucocorticoids.The reverse phase liquid chromatography system was equipped with C18 column and eluted with acetonitrile-H2O (40:60).Electrospray ionization (ESI) source was applied and operated in the positive ion mode.The prednisone acetate in the sample was identified by the retention time,precursor ion and daughter ion and six others not detected.To develop a HPLC ion trap tandem MS method for quantitative analysis of seven glucocorticoids.The reverse phase liquid chromatography system was equipped with C18 column and eluted with acetonitrile-H2O (40:60).Electrospray ionization (ESI) source was applied and operated in the positive ion mode.The prednisone acetate in the sample was identified by the retention time,precursor ion and daughter ion and six others not detected.

关 键 词：Ion trap IDENTIFICATION GLUCOCORTICOIDS 

分 类 号：O657-55[理学—分析化学]