焦虑症患者治疗前后感觉门控电位P50动态观察  

Follow-up study on sensory gating in anxiety disorder before and after treatment

作　　者：楼美珍[1] 吴亦[1] 马顺天[1] 陈冲[2] 

机构地区：[1]浙江省义乌市中心医院神经内科,322000 [2]上海交通大学医学院附属精神卫生中心

出　　处：《上海精神医学》2008年第2期85-87,共3页Shanghai Archives of Psychiatry

摘　　要：目的探讨焦虑症患者的感觉门控电位P50变异的意义。方法应用美国B ravo脑电生理仪,采用条件刺激(S1)—测试刺激(S2)模式对36例焦虑症患者作了P50检测。患者组于治疗10周时进行P50检测。结果焦虑症P50抑制明显减弱;S2-P50波幅正常人(2.2±0.9)μV,患者组(2.8±1.8)μV,P<0.05。患者组在治疗后的10周随访时的P50主要指标差异也无显著性(P>0.05)。结论P50变异也是焦虑症的特性,值得进一步随访。Objective: To investigate the auditory evoked potential P50 in anxiety disorder.Methods: P50 was recorded from 36 anxiety disorder and 45 normal controls with American Brova instrument.Results:Compared with NC,anxiety disorder showed sensory gating deficit,reflecting by increased S1-S2 ratio.anxiety disorder showed no difference with S1-S2 ration after 10 weeks of treatment(Before medication,S1-P50:(63±13)μV;at 10 weeks,(62±9)μV,P>0.05).Conclusion:The abnormal auditory P50 suppression occurred in the ear...

关 键 词：焦虑症 诱发电位 听觉 治疗结果 感觉门控P50 

分 类 号：R749.72[医药卫生—神经病学与精神病学]