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作 者:Baricault S. Soubrane J.C. Courville P. P. Joly 王琼
机构地区:[1]Clinique Dermatologique, Charles Nicolle, CHU de Rouen, 1, rue de Germont, 76031 Rouen Cedex
出 处:《世界核心医学期刊文摘(皮肤病学分册)》2006年第12期55-56,共2页Digest of the World Core Medical JOurnals:Dermatology
摘 要:Background. We report a case of necrolytic migratory erythema in a patient with Waldmann’s disease. Patients and methods. A 55-year-old male patient with a history of Waldmann’s disease was hospitalized for a rash on the trunk and limbs comprising annular polycyclic lesions with peripheral scaling evocative of necrolytic migratory erythema. High-protein and fatty-acid-supplemented parenteral feeding led to rapid improvement of the patient’s cutaneous lesions. Discussion. Waldmann’s disease is characterized by intestinal lymphatic abnormalities leading to exudative intestinal disease causing protein loss in the bowel lumen and deficient fatty acid absorption. The pathogenesis of necrolytic migratory erythema is not fully understood. Increased serum glucagon does not appear to be the only mechanism involved. The occurrence of necrolytic migratory erythema in a patient with Waldmann’s disease supports the current physiopathological hypothesis of the role of decreased plasma protein and amino acid levels in necrolytic migratory erythema.Background. We report a case of necrolytic migratory erythema in a patient with Waldmann s disease. Patients and methods. A 55-year-old male patient with a history of Waldmann s disease was hospitalized for a rash on the trunk and limbs comprising annular polycyclic lesions with peripheral scaling evocative of necrolytic migratory erythema. High-protein and fatty-acid-supplemented parenteral feeding led to rapid improvement of the patient s cutaneous lesions. Discussion. Waldmann s disease is characterized ...
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