核糖体-板层复合结构的诊断和病理学意义  

The significance of ribosome lamella complexes in diagnosis and pathology

作　　者：茹永新[1] 赵轼轩[1] 刘津华[1] 

机构地区：[1]中国医学科学院中国协和医科大学血液学研究所血液病医院电镜室,天津300020

出　　处：《白血病．淋巴瘤》2006年第4期298-300,共3页Journal of Leukemia & Lymphoma

摘　　要：回顾总结国内外有关核糖体-板层复合结构(RLC)的相关疾病报道,分析RLC的病理学意义和相关疾病种类。临床病例报告显示RLC多见于毛细胞白血病(HCL),但也散见于其他类型白血病和实体肿瘤;欧洲HCL患者RLC的阳性率在55%￣70%之间,但中国HCL患者中RLC阳性病例为26%。说明RLC作为HCL的电镜诊断标志在中国人中特异性不强,RLC的形成可能与肿瘤细胞的不对称分化、膜系统代谢紊乱有关。To summarize the diseases associated with ribosome lamella complexes (RLC) in domestic and foreign clinic reports, analyzing the pathology significance of RLC in variety diseases. The research demonstrates RLC most often found in hair cell leukemia (HCL), but it was also contained in many other kinds of leukemia and solid tumors. 26% of Chinese patients with HCL contained RLC, although it was 55 % ~ 70 % in European. The statistics suggests that RLC was not specific for diagnosis of RLC in Chinese people an...

关 键 词：核糖体-板层复合结构 诊断 病理学 毛细胞白血病 

分 类 号：R730.43[医药卫生—肿瘤]